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In Mexico, according to the National Institute of Statistics and Geography 2018, there are 4,057,719 microenterprises and 111,958 small and medium-sized enterprises (MiPyMES), these economic units contribute greatly to the gross domestic product (GDP) of most countries in the world, In our country, MSMEs are responsible for almost three quarters of total employment in Mexico. The sanitary measures that the public administration has imposed as a consequence of the spread of the COVID-19 virus have caused MSMEs to lose opportunities and have found it necessary to distribute their products through electronic commerce. Therefore, it is relevant to investigate the effect of the changes that MSMEs have faced in this context. The objective of this article is to evaluate the effect of Electronic Commerce through the dimensions: preparation of the company for electronic commerce, benefits of electronic commerce, barriers to electronic commerce, relationship between public policies and electronic commerce and the adoption of electronic commerce. electronically, in order to provide information that facilitates decision-making and the design of strategies related to electronic commerce. A descriptive statistical content analysis study was carried out, the data was collected through the application of surveys with a Likert scale to 100 companies in Tabasco, Mexico. The results indicate that 42% of those surveyed affirm that the company invests in computer equipment to participate in electronic commerce, 42% totally agree that the company has increased its sales thanks to online sales, 44% % of workers say they know the advantages of selling online, 46% say that the government does not provide companies with technology that encourages online sales. [ABSTRACT FROM AUTHOR]