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So far, about 770.1 million confirmed cases of COVID-19 have been counted by August 2023, and around 7 million deaths have been reported from these cases to the World Health Organization. In Ecuador, the first confirmed COVID-19 case was registered on 19 February 2020, and the country's mortality rate reached 0.43% with 12986 deaths, suggesting the need to establish a mechanism to show the virus spread in advance. This study aims to build a dynamic model adapted to health and socio-environmental variables as a multivariate model to understand the virus expansion among the population. The model is based on Susceptible-Infected-Recovered (SIR), which is a standard model in which the population is divided into six groups with parameters such as susceptible S(t), transit stage E(t), infected I(t), recovered R(t), deceased Me(t), infected asymptomatic Ia(t), infected symptomatic Is(t) and deceased by other causes M(t) to be considered and adapted. The model was validated by using consistent data from Chile and run by inconsistent data from Ecuador. The forecast error was analyzed based on the mean absolute error between real data and model forecast, showing errors within a range from 6.33% to 8.41% for Chile, with confidence a interval of 6.17%, then 3.87% to 4.70% range for Ecuador with a confidence interval of 2.59% until 23rd December 2020 of the database. The model forecasts exponential variations in biosecurity measures, exposed population, and vaccination. [ABSTRACT FROM AUTHOR]