1. COVID-19 Vaccine Effectiveness during a Prison Outbreak when Omicron was the Dominant Circulating Variant-Zambia, December 2021.
- Author
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Simwanza J, Hines JZ, Sinyange D, Sinyange N, Mulenga C, Hanyinza S, Sakubita P, Langa N, Nowa H, Gardner P, Saasa N, Chitempa G, Simpungwe J, Malambo W, Hamainza B, Chipimo PJ, Kapata N, Kapina M, Musonda K, Liwewe M, Mwale C, Fwoloshi S, Mulenga LB, Agolory S, Mukonka V, and Chilengi R
- Subjects
- Humans, Prisons, Case-Control Studies, Zambia epidemiology, Vaccine Efficacy, SARS-CoV-2, Disease Outbreaks prevention & control, COVID-19 Vaccines, COVID-19 epidemiology, COVID-19 prevention & control
- Abstract
During a COVID-19 outbreak in a prison in Zambia from December 14 to 19, 2021, a case-control study was done to measure vaccine effectiveness (VE) against infection and symptomatic infection, when the Omicron variant was the dominant circulating variant. Among 382 participants, 74.1% were fully vaccinated, and the median time since full vaccination was 54 days. There were no hospitalizations or deaths. COVID-19 VE against any SARS-CoV-2 infection was 64.8%, and VE against symptomatic SARS-CoV-2 infection was 72.9%. COVID-19 vaccination helped protect incarcerated persons against SARS-CoV-2 infection during an outbreak while Omicron was the dominant variant in Zambia. These findings provide important local evidence that might be used to increase COVID-19 vaccination in Zambia and other countries in Africa.
- Published
- 2022
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