1. Associations between HIV stigma and health-related quality-of-life among people living with HIV: cross-sectional analysis of data from HPTN 071 (PopART).
- Author
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Hall, Emily, Davis, Katherine, Ohrnberger, Julius, Pickles, Michael, Gregson, Simon, Thomas, Ranjeeta, Hargreaves, James R., Pliakas, Triantafyllos, Bwalya, Justin, Dunbar, Rory, Mainga, Tila, Shanaube, Kwame, Hoddinott, Graeme, Bond, Virginia, Bock, Peter, Ayles, Helen, Stangl, Anne L., Donnell, Deborah, Hayes, Richard, and Fidler, Sarah
- Subjects
HIV-positive persons ,CROSS-sectional method ,SOCIAL stigma ,QUALITY of life ,DATA analysis - Abstract
People living with HIV (PLHIV) report lower health-related quality-of-life (HRQoL) than HIV-negative people. HIV stigma may contribute to this. We explored the association between HIV stigma and HRQoL among PLHIV. We used cross-sectional data from 3991 randomly selected PLHIV who were surveyed in 2017–2018 for HPTN 071 (PopART), a cluster randomised trial in Zambia and South Africa. Participants were 18–44 years, had laboratory-confirmed HIV infection, and knew their status. HRQoL was measured using the EuroQol-5-dimensions-5-levels (EQ-5D-5L) questionnaire. Stigma outcomes included: internalised stigma, stigma experienced in the community, and stigma experienced in healthcare settings. Associations were examined using logistic regression. Participants who had experienced community stigma (n = 693/3991) had higher odds of reporting problems in at least one HRQoL domain, compared to those who had not (adjusted odds ratio, aOR: 1.51, 95% confidence interval, 95% Cl: 1.16–1.98, p = 0.002). Having experienced internalised stigma was also associated with reporting problems in at least one HRQoL domain (n = 552/3991, aOR: 1.98, 95% CI: 1.54–2.54, p < 0.001). However, having experienced stigma in a healthcare setting was less common (n = 158/3991) and not associated with HRQoL (aOR: 1.04, 95% CI: 0.68–1.58, p = 0.850). A stronger focus on interventions for internalised stigma and stigma experienced in the community is required. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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