Search

Background: The objective of this study was to investigate the association between periodontal status and non-alcoholic fatty liver disease (NAFLD) indicators in a representative Korean population.Methods: A cross-sectional study was conducted on 4061 participants >19 years of age using the 2010 Korea National Health and Nutrition Examination Survey data. Periodontal status was assessed by trained dentists using the community periodontal index. To identify the presence of NAFLD, biochemical data were defined using two validated indicators: the fatty liver index (FLI) and the hepatic steatosis index (HSI). The associations of the presence of periodontal pockets with FLI and HSI were evaluated by multivariable logistic regression analysis after adjusting for age, income, education level, smoking status, alcohol consumption, physical activity, diabetes mellitus, obesity, hypertension, and hypercholesterolemia.Results: The adjusted means in the FLI indicator increased in the presence of periodontal pockets, whereas there was no significant difference in the HSI (P = 0.005 for FLI; P = 0.142 for HSI). Periodontal pockets were consistently associated with the two NAFLD indicators in the sequential logistic models for women throughout the adjustment process. (OR = 1.77, 95% CI = 1.05 to 2.98 for FLI, OR = 1.64, 95% CI = 1.08 to 2.51 for HSI).Conclusions: Our findings showed that the presence of periodontal pockets may be independently associated with NAFLD indicators. Further study will be clarified by well-designed longitudinal studies. [ABSTRACT FROM AUTHOR]

Background: No studies have reported the association between the number of teeth and hypertension in the Korean national data. The purpose of this study was to investigate whether the number of teeth is associated with blood pressure and hypertension in a representative sample of the Korean population.Methods: A cross-sectional study was conducted on 13,561 participants aged ≥19 years using the 2012 to 2014 Korea National Health and Nutrition Examination Survey data. The number of teeth was divided into four groups: 0, 1 to 19, 20 to -27, and 28. The definition of hypertension was systolic blood pressure ≥140 mm Hg or diastolic blood pressure ≥90 mm Hg or being medicated for hypertension. Multivariate logistic regression analyses were performed after controlling for age, sex, income, education, smoking, drinking, diabetes mellitus, obesity, and hypercholesterolemia. Age- and sex-stratified analyses were performed.Results: The fully adjusted odds ratios (AOR) of the number of teeth group for hypertension were as follows: AOR: 1.25, 95% CI: 1.11 to 1.43 for 20 to 27 teeth; AOR: 1.46, 95% CI: 1.22 to 1.76; 1 to 19 teeth; and AOR: 1.63, 95% CI: 1.22 to 2.18 for edentulism. The strength of the association was highest in women aged ≥60 years across all age and sex groups (OR = 1.81, 95% CI = 1.15 to 2.86).Conclusion: Findings suggest that a decrease in the number of teeth may be independently associated with hypertension in the Korean population. [ABSTRACT FROM AUTHOR]

Objectives To assess the association between chewing difficulty and symptoms of depression in a representative sample of the Korean population. Design Cross-sectional. Setting Korea National Health and Nutrition Examination Survey ( KNHANES). Participants KNHANES participants (N = 5,158). Measurements Chewing difficulty was assessed according to the self-reported presence of chewing problems using a structured questionnaire. Symptoms of depression were defined as having feelings of sadness or depression consecutively over 2 weeks during the last 12 months. Multivariable logistic regression analysis was used to determine the adjusted odds ratios ( AORs) and 95% confidence intervals ( CIs) of the associations between chewing difficulty and symptoms of depression, adjusted for age; sex; monthly household income; education; number of teeth; number of decayed, missing, or filled permanent teeth; periodontitis; state of dentition; tooth brushing frequency; regular dental visits; smoking status; alcohol consumption; hypertension; diabetes mellitus; and obesity. The interaction effects between chewing difficulty and confounders were evaluated, and age- and sex-stratified analyses were performed. Results There was a significant positive association between chewing difficulty and symptoms of depression in the fully adjusted model ( AOR = 1.86, 95% CI = 1.48-2.33). The strength of the association was highest in men aged 60 and older ( AOR = 3.28, 95% CI = 1.54-7.00). Conclusion Chewing difficulty was independently associated with symptoms of depression in a representative sample of Korean adults. [ABSTRACT FROM AUTHOR]

Objectives This study aimed to evaluate the association between salivary 8-hydroxydeoxyguanosine (8- OHdG) and periodontitis among community-dwelling Korean adults. Methods A total of 211 adults (80 men and 131 women) were cross-sectionally surveyed from the Sunchang Longevity Cohort. Periodontitis was defined as having at least 30% of teeth with proximal attachment loss ≥5 mm. The salivary 8- OHdG level was categorized into tertiles: low (<0.916 ng/ml), medium (0.916 to <2.675 ng/ml) and high (≥2.675 ng/ml). Sociodemographic, habitual and systemic health-related factors were controlled for. Logistic regression analysis was performed for the outcome of severe periodontitis. Analysis of covariance in general linear model was performed for the outcome of 8- OHdG. Results The high 8- OHdG level showed a significant association with periodontitis. The odds ratio (95% confidence interval) was 2.40 (1.05-5.51), and it was highlighted by adding the interaction term with drinking and smoking. The adjusted mean log-transformed value of 8- OHdG was significantly higher in the severe periodontitis group (1.40 ng/ml) than in the control group (1.02 ng/ml) ( ancova, P = 0.028). Conclusions 8- OHdG was associated with periodontitis. Thus, salivary 8- OHdG could be a useful marker for periodontitis. [ABSTRACT FROM AUTHOR]

Objectives To investigate the association between periodontitis and cognitive impairment in elderly Koreans. Design Cross-sectional study with age- and sex-matched case-control selection. Setting The Yangpyeong cardiovascular cohort ( YCC), a part of the Korean Genome Epidemiologic Study (Ko GES), Yangpyeong, South Korea. Participants Individuals with cognitive impairment (n = 65) and cognitively normal controls (n = 124) aged 60 and older from the YCC. Measurements Alveolar bone loss was assessed on dental panoramic radiographs to categorize the cumulative history of periodontitis ( HOP) into three groups: normal, moderate periodontitis, severe periodontitis. The Mini-Mental State Examination ( MMSE) was used to categorize participants as cognitively normal or cognitively impaired. Age- and sex-matched conditional logistic regression models were used for analysis. Confounders considered in the analysis were age, sex, drinking, smoking, exercise, total cholesterol, total protein, body mass index, fasting plasma glucose, intima-media thickness, hypertension medication, and depression. Results Participants with HOP were more likely to have cognitive impairment than those without (odds ratio = 2.14, 95% confidence interval = 1.04-4.41). The interaction effect of smoking and exercise on periodontitis highlighted the link. Conclusion Periodontitis was independently associated with cognitive impairment after controlling for various confounders. Further longitudinal research is needed to determine whether periodontitis plays a role in cognitive decline in older adults. [ABSTRACT FROM AUTHOR]