1. Hyperpolarized 129Xe Magnetic Resonance Imaging Sensor for H2S.
- Author
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Yang, Shengjun, Yuan, Yaping, Jiang, Weiping, Ren, Lili, Deng, He, Bouchard, Louis S., Zhou, Xin, and Liu, Maili
- Subjects
MAGNETIC resonance imaging ,DETECTORS ,HYDROGEN sulfide ,NUCLEAR magnetic resonance ,CRYPTOPHANE - Abstract
A new magnetic resonance imaging (MRI) molecular sensor for hydrogen sulfide detection and imaging using the nuclear spin resonance of hyperpolarized
129 Xe is developed. The designed MRI sensor employs cryptophane for NMR sensing, together with an azide group serving as a reaction site. It demonstrates a 'proof-of-concept' that a fluorescent H2 S probe can be linked to a xenon-binding cryptophane and thereby converted into an MRI probe, which could provide a very generalizable template. [ABSTRACT FROM AUTHOR]- Published
- 2017
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