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Dipyridyl sulphide ligands 4-(pyridin-4-ylmethylthio)pyridine (abbreviated as L1) and 3-(pyridin-4-ylmethylthio)pyridine (abbreviated as L2) have been designed and used as μ- N , N -bridging linkages to construct coordination polymers with free –S–CH 2 – groups as secondary donor sites. By use solvent control method, coordination polymers {[Ag 3 SO 4 (L1) 3 ](Cl)·4.5H 2 O} ∞ ( 1 ), {[Ag 2 SO 4 (L1) 2 ]·6H 2 O·2CH 3 OH} ∞ ( 2 ), {[Ag 2 SO 4 (L2) 2 ]·H 2 O} ∞ ( 3 ) and {[Ag 4 (SO 4 ) 2 (L2) 4 ]·5H 2 O} ∞ ( 4 ) with different architectures were obtained. Complexes 1 , 3 and 4 feature 1D channel with different sizes and structures. Complex 1 exhibits guest exchange by THF and 1,4-dioxane, and Hg 2+ sorption ability from solution due to its relative larger channel and available bonding sites of –S– exposed to the channel region. All complexes have been characterized through single-crystal and powder X-ray diffraction (PXRD), FT-IR spectra, X-ray photoelectron spectroscopy (XPS), elemental and thermogravimetric analyses. The guest exchange and Hg 2+ sorption were monitored and identified, and the structure-property relationship of coordination polymers 1–4 are discussed. [ABSTRACT FROM AUTHOR]

A family of Ag(I) complexes constructed from the unsymmetrical bent-shaped ligand 2-(pyridine-4-ylthio)pyrazine (abbreviated as 2-PTP), namely [Ag(2-PTP) 2 ]·ClO 4 ( 1 ), {[Ag 2 (2-PTP) 2 (CF 3 CO 2 ) 2 ]·(H 2 O)} ∞ ( 2 ), {[Ag(2-PTP)(NO 2 )]} ∞ ( 3 ), {[Ag 3 (2-PTP) 2 (CF 3 SO 3 ) 2 ]·(CF 3 SO 3 )·(H 2 O)} ∞ ( 4 ) and {[Ag 2 (2-PTP) 2 (SO 4 )]·9H 2 O} ∞ ( 5 ), has been synthesized by varying the silver(I) salts. These complexes have been characterized by single crystal X-ray diffraction, FT-IR spectra and elemental analyses. In 1 – 5 , the 2-PTP ligand adopts versatile coordination modes with various silver(I) salts to generate a series of supramolecular architectures. Weak interactions, such as hydrogen bonding and π ⋯ π interactions, have been described in detail. The anion influence on the structural diversities of 1 – 5 has also been discussed. [ABSTRACT FROM AUTHOR]

C11H10N2OS, monoclinic, Pc (no. 7), a = 12.050(3) Å, b = 5.5218(13) Å, c = 8.1813(19) Å, β = 107.934(6)°, V = 517.9(2) Å3, Z = 2, Rgt (F) = 0.0483, wRref (F2 ) = 0.1247, T = 296 K. [ABSTRACT FROM AUTHOR]

The article discusses the crystal structure of the title compound bis(di(pyrazin-2-yl)sulfane-ĸN)tetrakis(μ2-acetato-ĸ2O:O'dicopper(II) (C12H12CuN4O4S). Topics discussed include the synthesis of the title compound, experimental data, and refinement. Also provided are the supplementary materials which include fractional atomic coordinates, atomic displacement parameters, and geometric parameters.

C11H6AgF5N4O2S, monoclinic, P21/m (No. 11), a = 5.962(3) Å, b = 13.088(6)Å, c = 9.339(4)Å, β = 105.449(5)°, V = 702.4 Å3, Z = 2, Rgt(F) = 0.0214, wRref(F2) = 0.0556, T = 296 K. [ABSTRACT FROM AUTHOR]

Two new platinum(II) complexes 7a and 7b with methyl hydrazinecarbodithioate derivatives of indolin-2-one have been prepared and characterized by single-crystal X-ray diffraction, NMR spectroscopy and mass spectrometry. Antiproliferative activity of the two complexes and their ligands 6a and 6b against HCT-116, MCF-7 and MDA-MB-231 cell lines was determined by the MTS assay. Complexes 7a and 7b exhibited stronger antiproliferative activity against three cell lines than compounds 6a and 6b (IC 50 , 1.89–5.60 versus 6.52–35.13 μM). Moreover, treatment of HCT-116 cells with the complexes resulted in an obvious sub-G1 peak by cell cycle profile analysis, and an increase of cleaved PARP1 and caspases 3, 7, and 9 by immunoblotting analysis. Live cell imaging showed that nucleus shrinkage and condensation started to appear when MCF-7 cells were treated with 7a for 8 h. Fluorescent spectrophotometric analysis revealed that the complexes physically associated with calf thymus DNA. Competitive DNA binding assays uncovered that the complexes non-covalently bind to DNA. Taken together, our results indicated that the two new platinum(II) complexes 7a and 7b non-covalently bind to DNA with high affinity and exhibit cytotoxicity against cancer cells by inducing apoptosis. [ABSTRACT FROM AUTHOR]

Abstract: A series of silver(I) complexes bearing the V-shaped di-4-pyridyl sulfone-N,N′-dioxide ligand (abbreviated as L), namely [Ag(L)(NO3)(H2O)]∞ (1), [Ag(L)(CF3SO3)]∞ (2), [Ag(L)(CF3CO2)]∞ (3), [Ag(L)(C2F5CO2)]∞ (4) and {[Ag(L)](ClO4)}∞ (5), and the manganese(II) complex [Mn(L)2(H2O)4](ClO4)2 (6) and the zinc(II) complex [Zn(L)2(H2O)4](ClO4)2 (7) of L have been synthesized and characterized. Under the tuning effect of anions with different coordination capacities and steric bulk, the semi-rigid ligand L exhibits versatile μ2-, μ3- and μ4-bridging modes with the N-oxide and/or sulfonyl O atoms functioning as bonding sites to form a coordination chain structure in complex 1, isostructural nets in 2–4, and a three-dimensional framework in 5. The isostructural mononuclear complexes 6 and 7 exhibit the η1–ON-oxide bonding mode of L. Unusual lone-pair aromatic contacts and anion–π interactions result in supramolecular aggregations of complexes 1–7. The FT-IR spectra and luminescent properties of these complexes have been observed and discussed. [Copyright &y& Elsevier]