1. Angiogenic Cytokine Profile of a Patient With Schwartz-Matsuo Syndrome.
- Author
-
Fan W, Zheng X, Yuan S, Xie P, and Liu Q
- Subjects
- Adult, Biomarkers metabolism, Diagnosis, Differential, Glaucoma, Open-Angle complications, Glaucoma, Open-Angle metabolism, Humans, Male, Microscopy, Acoustic, Microscopy, Electron, Retinal Detachment complications, Retinal Detachment metabolism, Retinal Photoreceptor Cell Outer Segment ultrastructure, Syndrome, Aqueous Humor metabolism, Cytokines metabolism, Glaucoma, Open-Angle diagnosis, Intraocular Pressure physiology, Retinal Detachment diagnosis
- Abstract
A 36-year-old man was diagnosed with Schwartz-Matsuo syndrome and received a scleral buckle surgery. Photoreceptor outer segments in aqueous humor were examined under electron microscope to confirm the diagnosis. Afterwards, 17 human angiogenesis and growth factor biomarkers were chosen to make simultaneous quantification in aqueous humor, among which the authors demonstrated the remarkable high expression of angiopoietin-2 in aqueous humor. This is the first reported case of angiogenesis / growth factor biomarkers in aqueous humor of the Schwartz-Matsuo Syndrome patient. Angiopoietin-2 level significantly increased in this patient's aqueous humor, which helped the authors to illuminate the pathogenic mechanisms underlying Schwartz-Matsuo syndrome. [Ophthalmic Surg Lasers Imaging Retina. 2018;49:721-725.]., (Copyright 2018, SLACK Incorporated.)
- Published
- 2018
- Full Text
- View/download PDF