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According to recent research from Granada, Spain, 'The growth hormone (GH) stimulation test shows that hypoglycaemia can cause the generation of free radicals, or reactive oxygen species (ROS), together with [...]

According to recent research from the United States, 'This study assessed the role of oxidative stress and loss of glutathione in ABT-737-induced apoptosis. Jurkat human acute lymphocytic leukemia cells and [...]

According to recent research from Valencia, Spain, 'Insulin resistance is a feature of polycystic ovary syndrome (PCOS) and is related to mitochondrial function. Our objective was to assess mitochondrial function [...]

'A cell culture of Picea abies (L.) Karst. was used for studies of H2O2 generation during constitutive extracellular lignin formation and after elicitation by cell wall fragments of a pathogenic [...]

According to recent research from the United States, 'The ubiquitous tripeptide glutathione (GSH) is an essential factor in many biological processes, thus its depletion has a major impact on cell [...]

According to recent research published in the journal Cell Biology and Toxicology, 'Rifampicin-induced hepatotoxicity has been well recognized in animals and patients. However, it is undetectable in cultured hepatocyte monolayers [...]

According to recent research from the United States, '3H-1,2-dithiole-3-thione (D3T), a cruciferous organosulfur compound, induces cytoprotective enzymes in animal cardiovascular cells. However, it remains unknown if D3T also upregulates antioxidants [...]

'The aim of this study was to investigate high molecular weight hyaluronan (HMW-HA) protection on human corneal epithelial (HCE) cells against ultraviolet B (UVB) radiation-induced toxic effects. The HCE cell [...]

'In Saccharomyces cerevisiae, accumulation of cadmium-glutathione complex in cytoplasm inhibits cadmium absorption, glutathione transferase 2 is required for the formation of the complex and the vacuolar gamma-glutamyl transferase participates of [...]

Scientists discuss in 'Mitochondrial glutathione uptake: characterization in isolated brain mitochondria and astrocytes in culture' new findings in life sciences. 'Glutathione in the mitochondria is an important determinant of cellular [...]

'It is widely accepted that the redox status of protein thiols is of central importance to protein structure and folding and that glutathione is an important low-molecular-mass redox regulator. However, [...]

According to recent research from Yangzhou, People's Republic of China, 'Cadmium (Cd) is a known nephrotoxic element. In this study, the primary cultures of rat proximal tubular (rPT) cells were [...]

Investigators publish new data in the report 'Effects of 2(RS)-n-propylthiazolidine-4(R)-carboxylic acid on 4-hydroxy-2-nonenal-induced apoptotic T cell death.' According to recent research published in the Journal of Nutritional Biochemistry, '4-Hydroxy-2-nonenal (HNE), [...]

Data detailed in 'Gamma-glutamyltransferase is upregulated after oxidative stress through the Ras signal transduction pathway in rat colon carcinoma cells' have been presented (see also Enzyme Research). 'Gamma-glutamyltransferase (GGT) plays [...]

'Glutamate, a major excitatory neurotransmitter in the CNS, plays a critical role in neurological disorders such as stroke and Parkinson's disease (see also Necroptosis). Recent studies have suggested that glutamate [...]

'Glutathione (GSH) is an abundant antioxidant ubiquitous in nearly all cell types (see also Ocular Research). Deficiency of GSH has been linked to ocular disease and viral infection,' investigators in [...]

According to recent research from India, 'UV-B induces lipid peroxidation and oxidative stress in mammalian cells by producing reactive oxygen species (see also Diet and Nutrition). In this present study, [...]

According to recent research from the United States, 'Selenoprotein His a recently identified member of the selenoprotein family whose function is not fully known (see also Biological Chemistry). Previous studies [...]

According to recent research from Nanjing, People's Republic of China, ''Human T-cell leukemia is a malignant disease that needs various regimens of cytotoxic chemotherapy to overcome drug resistance (see also [...]

'Two sets of mice (Mus musculus) were chronically fed 0.06% p-dimethylaminoazobenzene (p-DAB) and 0.05% Phenobarbital (PB) for 90 and 120 days, respectively, and several cell biological and hematological parameters were [...]

Research findings, 'Knock down of gamma-glutamylcysteine synthetase in rat causes acetaminophen-induced hepatotoxicity,' are discussed in a new report (see also Biological Chemistry). 'Drug-induced hepatotoxicity is mainly caused by hepatic glutathione [...]

New findings from University of California, U.S., described. This trend article about University of California, U.S., is an immediate alert from NewsRx to identify developing directions of research. Study 1: [...]

New investigation results, 'Upregulation of cerebral cortical glutathione synthesis by ammonia in vivo and in cultured glial cells: the role of cystine uptake,' are detailed in a study published in [...]

New investigation results, 'Glutathione depletion inhibits dendritic cell maturation and delayed-type hypersensitivity: implications for systemic disease and immunosenescence,' are detailed in a study published in The Journal of Allergy and [...]

Findings from studies by Monash University, Australia, scientists provide new insights. This trend article about Monash University, Australia, is an immediate alert from NewsRx to identify developing directions of research. [...]

Investigators in Scotland, the People's Republic of China and Japan have published new apoptosis data. Study 1: Antimonial compounds may work by disrupting thiol homeostasis. According to recent research published [...]