1. Association between mechanical power during one-lung ventilation and pulmonary complications after thoracoscopic lung resection surgery: a prospective observational study.
- Author
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Liu, Hong-Mei, Zhang, Gong-Wei, Yu, Hong, Li, Xue-Fei, and Yu, Hai
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VIDEO-assisted thoracic surgery , *PEARSON correlation (Statistics) , *T-test (Statistics) , *STATISTICAL significance , *SCIENTIFIC observation , *MULTIPLE regression analysis , *FISHER exact test , *MULTIVARIATE analysis , *MANN Whitney U Test , *DESCRIPTIVE statistics , *SURGICAL complications , *LONGITUDINAL method , *ODDS ratio , *LUNG diseases , *THORACOSCOPY , *ARTIFICIAL respiration , *STATISTICS , *CONFIDENCE intervals , *DATA analysis software , *PNEUMONECTOMY , *RESPIRATORY mechanics - Abstract
Background: The role of mechanical power on pulmonary outcomes after thoracic surgery with one-lung ventilation was unclear. We investigated the association between mechanical power and postoperative pulmonary complications in patients undergoing thoracoscopic lung resection surgery. Methods: In this single-center, prospective observational study, 622 patients scheduled for thoracoscopic lung resection surgery were included. Volume control mode with lung protective ventilation strategies were implemented in all participants. The primary endpoint was a composite of postoperative pulmonary complications during hospital stay. Multivariable logistic regression models were used to evaluate the association between mechanical power and outcomes. Results: The incidence of pulmonary complications after surgery during hospital stay was 24.6% (150 of 609 patients). The multivariable analysis showed that there was no link between mechanical power and postoperative pulmonary complications. Conclusions: In patients undergoing thoracoscopic lung resection with standardized lung-protective ventilation, no association was found between mechanical power and postoperative pulmonary complications. Trial registration: Trial registration number: ChiCTR2200058528, date of registration: April 10, 2022. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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