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In job-shop production systems, orders are assigned to work centers according to their routes, and their operations are performed in this order. Production is becoming more and more complex with the increasing number of product lines and work centers with different routes. Decisions to be made according to the real-time monitoring of a dynamic production environment have become important. With the Fourth Industrial Revolution, information technologies are widely used in industries. A large amount of data is obtained from production tools that are capable of communicating with each other by means of Industry 4.0 and the internet of things. In this study, a simulation model of a production system that can collect data in real-time via sensors in work centers has been created and operation conditions have been determined. Then, work center / machine loading strategies were compared according to the delay periods of the jobs. The simulation model with the best loading strategy was run according to three different demand rates. Then data related with the delay status of the orders and the status of the work centers was obtained. The data were evaluated with data mining classification algorithms and rules were determined for delayed jobs. These rules were added to the simulation model as a decision mechanism. When an order is received in this model, the expert system estimates whether or not there will be a delay, and makes a decision to outsource the order's production if needed. This approach further reduces the number of delayed orders [ABSTRACT FROM AUTHOR]