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Objective: Preoperative seizures are a common symptom in meningioma patients. Known risk factors include radiological features, localization but also WHO grading. Recently, brain invasion was added as an independent criterion for WHO II meningioma and its clinical importance was questioned in subsequent[for full text, please go to the a.m. URL], 71. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), 9. Joint Meeting mit der Japanischen Gesellschaft für Neurochirurgie

Objective: Patients with glioblastoma (GBM) continue to have an unfavorable prognosis. A novel therapeutic approach is pursued with interstitial photodynamic therapy (PDT). After oral administration of a photosensitizing substance, the tumor is irradiated using stereotactically inserted laser probes.[for full text, please go to the a.m. URL], 70. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Skandinavischen Gesellschaft für Neurochirurgie

Background: Spinal glioma are rare and their biological behavior can differ from their cerebral counterparts. Pilomyxoid astrocytoma (PMA, WHO °II) typically occur in the hypothalamic/chiasmatic region of children. The few reported cases of pediatric spinal PMA displayed a particularly aggressive[for full text, please go to the a.m. URL], 57th Annual Meeting of the German Society for Neuropathology and Neuroanatomy (DGNN)

Objective: Three different uptake patterns of O-(2-[(18)F]fluoroethyl)-l-tyrosine (18FET) have been shown to occur in patients with suspected WHO II glioma after dynamic PET evaluation: 1) a constantly increasing uptake throughout the entire tumor volume indicative for a grade II glioma. 2)[for full text, please go to the a.m. URL], 63. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Japanischen Gesellschaft für Neurochirurgie (JNS)

Objective: Metabolic imaging such as O-(2-18F-fluoroethyl)-L thyrosine (FET) positron emission tomography (PET) often revealed heterogeneous findings in suspected WHO grade II glioma showing one or more HOT-SPOT area(s). To which extent these HOT-SPOTS correlate with malignant tumour parts, has never[for full text, please go to the a.m. URL], 60. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit den Benelux-Ländern und Bulgarien

Objective: Histological grading of gliomas is mandatory to assess prognosis and determine treatment concepts. Conventional MRI using T1 (± gadolinium) and T2 sequences lacks diagnostic sensitivity and specificity. Significant diagnostic improvement has been shown for metabolic imaging such as [18F]-fluoroethyl-thyrosine[for full text, please go to the a.m. URL], 60. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit den Benelux-Ländern und Bulgarien

Objective: Epigenetic silencing of the MGMT gene has been linked to favorable prognosis in glioblastomas (GBM) after treatment according to the EORTC protocol even when stratified for the extent of surgery except for patients who undergo biopsy only. Aim of this study was to evaluate the prognostic [for full text, please go to the a.m. URL], 60. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit den Benelux-Ländern und Bulgarien