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Objective: The determination of the presence of tumor in biopsies and the decision-making during resections is often dependent on intraoperative histological tissue sample assessment. Recently, stimulated Raman scattering microscopy has been introduced to rapidly generate virtual hematoxylin-and-eosin-stained-like [for full text, please go to the a.m. URL]

Objective: That the number of brain metastases (BM) is included in prognostic assessment models for patients with non-small cell lung cancer (NSCLC). However, the underlying data were generated in an era with limited systemic treatment options. With rapidly changing treatment modalities based on a growing [for full text, please go to the a.m. URL]

Objective: Surgical options for treating brainstem metastases (BSM) are limited. As an alternative to local or whole brain radiation therapy, stereotactic radiosurgery (SRS) can be applied for the treatment of BSM. However, especially in brainstem the applied dose has to be balanced between toxicity[for full text, please go to the a.m. URL], 72. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Polnischen Gesellschaft für Neurochirurgie

Objective: The treatment of symptomatic, progressive or recurrent acquired intracerebral cysts is challenging especially when localized in eloquent or deep-seated midline structures. Hereby, the frame-based stereotactic implantation of cysto-ventricular shunts offers a minimally invasive and highly [for full text, please go to the a.m. URL], 72. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Polnischen Gesellschaft für Neurochirurgie

Objective: The development of robotic systems has brought an alternative to frame-based stereotactic procedures. In this experimental setting we aim to reduce procedural errors to a minimum when comparing the ROSA robot and the Leksell stereotactic system regarding mechanical accuracy. Methods:[for full text, please go to the a.m. URL], 72. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Polnischen Gesellschaft für Neurochirurgie

Objective: Prognosis for patients with metastatic melanoma has substantially changed due to novel medical and radiosurgical approaches. In this context, a cerebral metastectomy is rarely performed compared to other tumor entities, but is still indicated in large and/or symptomatic tumors or tumor[for full text, please go to the a.m. URL], 71. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), 9. Joint Meeting mit der Japanischen Gesellschaft für Neurochirurgie

Objective: The use of single fraction stereotactic radiosurgery (SRS) is limited by tumor size (>3cm) and/or close proximity to critical structures (e.g. cranial nerves/optical pathway/pituitary gland). Here we present data regarding hypofractionated SRS (hSRS) for the treatment [for full text, please go to the a.m. URL], 69. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Mexikanischen und Kolumbianischen Gesellschaft für Neurochirurgie

Objective: Microsurgical resection of cavernous sinus meningiomas (CSM) is challenging with a high percentage of recurrence due to incomplete resection (>10% reported recurrence rate after Simpson Grade II and >20% after Grade III resections) and/or permanent, partly severe [for full text, please go to the a.m. URL], 68. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), 7. Joint Meeting mit der Society of British Neurological Surgeons (SBNS)

Objective: Microsurgical resection of solely intracanalicular acoustic neurinoma (iAN) is challenging. The risk of hearing loss is described with up to 40% and N. VII disturbance ranging from 4 -16%. Stereotactic Radiosurgery (SRS) has evolved as alternative first-line treatment for small [for full text, please go to the a.m. URL], 67. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), 1. Joint Meeting mit der Koreanischen Gesellschaft für Neurochirurgie (KNS)

Objective: To establish a definite diagnosis histological, immunological and molecular evaluation of tissue remains despite improvement of modern imaging the gold standard for unclear lesions/tumors in the brain. Stereotactically guided biopsy serves to obtain tissue, especialley in areas not accessible[for full text, please go to the a.m. URL], 67. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), 1. Joint Meeting mit der Koreanischen Gesellschaft für Neurochirurgie (KNS)

Objective: Recent studies have shed light on the molecular makeup and led to the identification of potential treatment targets for diffuse intrinsic pontine gliomas, which account for the majority of pediatric brainstem tumors (pedBSTs). Therefore, stereotactic biopsy driven molecular characterization[for full text, please go to the a.m. URL], 67. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), 1. Joint Meeting mit der Koreanischen Gesellschaft für Neurochirurgie (KNS)

Objective: While stereotactic biopsies (SB) are widely accepted as routine diagnostic tool for unclear cerebral pathologies in adult patients, there is still a certain reluctance to apply this technique for the pediatric population. Probable reasons might be the localization of pathologies predominantly[for full text, please go to the a.m. URL], 66. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC)

Objective: The aim of this study was to investigate the potential of [18F]fluoroethyl-L-tyrosine (18F-FET) PET for differentiating local recurrent brain metastasis from radiation-induced changes after radiation therapy since the use of contrast-enhanced MRI for this issue is often difficult.[for full text, please go to the a.m. URL], 65. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC)

Objective: Despite advances in preoperative (functional) imaging and the use of intraoperative guidance and mapping techniques, gliomas located in the area of the central sulcus are still a big challenge for resective surgery due to a high risk of severe neurological deficits. Stereotactic brachytherapy[for full text, please go to the a.m. URL], 62. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Polnischen Gesellschaft für Neurochirurgen (PNCH)

Objective: To report ont stereotactic 125Iodine brachytherapy (SBT) for the treatment of singular cerebral metastases regarding feasibility, survival and cerebral disease control, in order to identify prognostic factors and to compare results with other local treatment methods. Methods: Complications,[for full text, please go to the a.m. URL], 61. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC) im Rahmen der Neurowoche 2010