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Studies the effects of aromatic stacking interactions on the stabilization of reduced flavin adenine dinucleotide and substrate/product in Megasphaera elsdenii short-chain acyl-coenzyme A dehydrogenase. Mutations at the aromatic residues; Electrochemical properties of the mutants; Disruption of the interactions; Formation of product.

Examines the reduction-oxidation reaction and ionization properties of medium-chain acyl-coenzyme A dehydrogenase (MCAD). Use of 2,4-Hexadienoyl-coenzyme A (HD-CoA); Formation of medium-chain Acyl-CoA-HD-CoA complex; Effects of hydrogen-ion concentration on redox potential of hexadienoyl-CoA-complexed MCAD.

Examines the biochemical behavior of the acyl-CoA dehydrogenase family toward the molecular oxygen. Suppression of reactivity of reduced enzyme toward molecular oxygen; Why a series of redox inactive acyl-CoA analogues was tested; Information on acyl-CoA dehydrogenase.