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Start Over Author "Tajouri, L." Topic demyelination Topic methylation

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1. Methylation differences at the HLA-DRB1 locus in CD4+ T-Cells are associated with multiple sclerosis.

Author

Graves, MC, Benton, M, Lea, RA, Boyle, M, Tajouri, L, Macartney-Coxson, D, Scott, RJ, and Lechner-Scott, J

Subjects
*MULTIPLE sclerosis, *DEMYELINATION, *MYELIN sheath diseases, *T cells, *LYMPHOCYTES
Abstract

The article examines the methylation changes associated with multiple sclerosis (MS) through a genome-wide DNA methylation analysis of CD4+ T cells. The cells were taken from 30 patients with relapsing-remitting MS and 28 healthy controls using Illumina 450K methylation arrays. Environmental and genetic factors are said to influence the risk of developing MS.

Published
2014
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