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Background: This study aimed to assess the effect of the "cut-out rescan" strategy on the accuracy of intraoral digital scans from 25° convergent implants positioned at two distinct depths., Material and Methods: Two customized models were fabricated, each designated to receive two posterior converged implant fixtures: one at a depth of 1 mm and the other at a depth of 4 mm. Initially, the models were scanned as reference casts using a lab scanner. The test group was involved in scanning the 1-mm and 4-mm implant models using an intraoral scanner in the following order: (1) scanning the 1-mm (T1; n = 10) and (2) 4-mm (T4; n = 10) implant groups with scan bodies connected to both fixtures in each model; (3) cut-out rescan (COR) in the 1-mm (COR1; n = 10) and (4) 4-mm (COR4; n = 10) models, leading to 40 digital files in standard tessellation language format. The mean absolute deviation (MAD), in terms of trueness and precision, between the experimental and control scans was assessed through the alignment of their respective datasets using three-dimensional analysis software. Two-way analysis of variance (ANOVA) and Levene's tests were used to analyze the data., Results: The COR4 group exhibited the highest MAD, indicative of both trueness and precision (Mean ±SD: 55.659 ±34.802). In contrast, the T1 group demonstrated the lowest MAD (Mean ±SD: 43.225 ±19.237). However, the ANOVA analysis showed no significant influence of depth (P = 0.506) or type of scan (P = 0.442) on the MAD. Precision also did not differ significantly across groups (P = 0.071)., Conclusions: The cut-out rescan approach demonstrated an accuracy comparable to that of the one-time scan method., Clinical Significance: Digital intraoral scanning provides clinicians with a range of tools to navigate challenging conditions in which conventional methods may prove difficult, such as cases involving angled adjacent implants. In these scenarios, the cut-out rescan tool serves as a valuable resource, aiding clinicians in overcoming the challenges associated with impression-making owing to the convergence of placed implants., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 The Author(s). Published by Elsevier Ltd.. All rights reserved.)

Background: The purpose of this pilot in-vitro study was to assess the effect of sterilization on the intra-implant axis, inter-implant axis, intra-implant distance and inter-implant distance of three implants in a straight line by using laboratory scanner (LBS) versus intra-oral scanner (IOS) with intra-oral scan bodies (ISB)., Methods: A printed 3D model with three internal hex analogs in the positions 15#,16#,17# was used. Zirkonzhan (ZZ) intra-oral scan body (ISB), two-piece titanium was used. The ZZ ISBs were scanned by 7 Series dental wings (LBS) and 30 times by Primescan (IOS) pre sterilization and 30 times post sterilization. For each scan (pre and post) stereolithography (STL) file was created and a comparison between all the scans pre sterilization and post sterilization were superimposed on the laboratory scan by using a 3D analyzing software. A Kolmogorov-Smirnov test performed followed by Wilcoxon Signed Ranks tests. (p < 0.05) Results: Post sterilization of the ZZ ISB, the mean errors were significantly increased for the inter-implant distances (p < 0.0005), intra-implant distances 1,2,3 (p < 0.0005), intra-implant axis 1,3 (p < 0.0005) and inter-implant axes 13,23 (p < 0.05). In contrast, the mean errors for intra-implant axis 2 (p < 0.0005) and inter-implant axis 12 (p < 0.0005) were significantly reduced., Conclusions: ZZ ISB showed changes in all four parameters after sterilization. The middle ISB had the largest changes in mean error regarding all four parameters. Sterilization process may affect the three-dimensional (3D) structure of the ZZ ISB after three cycles. There is a lack in the literature in this field and there is a need for further studies to explore the effect of sterilization (multiple cycles) on different ISBs and for creating an approved guidelines regarding the amount of sterilization for each ISB in the industry., (© 2024. The Author(s).)

Accuracy is a necessity in implant impressions to fabricate accurately fitting implant-supported prostheses. This in vitro study aimed to explore the impact of the number of scan bodies on scanning quality by comparing scans of 2 vs 4 implants, and to determine if their accuracy and precision meets acceptable clinical threshold. Two mandibular edentulous models were used: one with 4-parallel implants (4-IM) and the other with 2-parallel implants (2-IM). Each model was scanned 10 times with an intraoral scanner, while reference scans were obtained with a high-precision laboratory scanner. The accuracy of test scans was evaluated by superimposing them onto reference scans and measuring 3D and angular deviations of the scan bodies. To assess the precision, the repeatability of the scans was analyzed by measuring the 3D SDs. Independent t test was used to compare angular deviations, the Mann-Whitney U test was used for 3D deviations and 3D SDs, and 1 sample t test was used for comparing means to the clinical threshold. Angular and 3D deviations were statistically not significant between the 2 groups (P = .054 and 0.143). 3D deviation values were higher than the 150-µm threshold for 2-IM (201 µm) and 4-IM (290 µm); angular deviation in 2-IM was 0.600 degrees and 0.885 degrees for 4-IM. There was no statistically significant difference in the precision of scans between the 2 groups. (P = .161). Although scanning quality improved when 2 scan bodies were used, the difference was not statistically significant. Moreover, full-arch implant scanning did not meet acceptable levels of accuracy and precision.

Background: Lithium disilicate can be reliable when restoring implants in the esthetic zone. However, it has a high elastic modulus. This might increase the amount of forces transmitted to the crestal bone., Aim of the Study: To evaluate the crestal bone loss and peri-implant periodontal parameters of polymer infiltrated ceramic network compared to lithium disilicate implant-supported hybrid abutment crowns after 12 months of follow-up., Methodology: 44 patients were enrolled. They were randomly assigned into two groups (n = 22). The first group received 22 implants restored with polymer-infiltrated ceramic network (Vitaenamic) hybrid abutment crowns. The second group received 22 implants restored with lithium disilicate (e.max) hybrid abutment crowns over immediately placed implants in the esthetic zone. Periapical radiographs were taken immediately after prosthetic placement and 1 year later utilizing a parallel technique, to assess crestal bone loss. Periodontal parameters were assessed after 1 year., Results: Regarding crestal bone loss, a comparison between group I (Vitaenamic) and group II (e.max) was made by using an Independent t-test, which showed an insignificant difference between them (p > 0.05). A comparison between groups I and II revealed insignificant differences regarding periodontal parameters (probing depth, bleeding on probing, visible plaque, and suppuration)., Conclusions: Regarding bone stability and periodontal parameters, polymer infiltrated ceramic network and lithium disilicate hybrid abutment crowns showed comparable results. Both materials showed clinically acceptable hard and soft tissue responses., (© 2023 Wiley Periodicals LLC.)

Purpose: A high transfer accuracy of the intraoral implant position to a model is required, to manufacture implant-supported restorations. However, clinically relevant deviations persist between the intraoral implant position and the model obtained, even for the benchmark conventional custom implant impressions with polyether. Thus, new approaches using 3-D printed impression trays may increase the transfer accuracy of implant impressions. The ability to adjust parameters such as the thickness of the layers and the influence of the openings in the impression tray could potentially affect accuracy., Methods: Four different types of impression trays (n = 10 for each group) for the conventional impression technique were investigated: conventional custom impression tray, customized foil tray, chairside 3-D printed impression tray with the SHERA system, and the Primeprint system using an implant master model with four implants in the posterior region and a reference cube. After plaster model casting, all models were measured using a coordinate measuring machine, and the deviation from the reference dataset was determined. A statistical ANOVA analysis was performed (p < 0.05)., Results: Chairside 3-D printed impression trays showed the best results, followed by conventional custom impression trays. Implant impressions obtained using a customized foil tray exhibited the lowest accuracy. Statistically significant differences were observed between 3-D printed impression trays and conventional custom impression and customized foil trays (p < 0.05). Whereas, the implant position did not have any significant influence on accuracy (p > 0.05)., Conclusions: Chairside 3-D printed impression trays significantly increase the transfer accuracy for implant impression taking., (© 2023. The Author(s).)

Objectives: The present study aimed to systematically review the current randomized clinical trials (RCTs) with respect to computer-aided design/computer-aided manufactured (CAD/CAM) techniques in the process of implant planning, placement, and rehabilitation., Materials and Methods: Four independent reviewers conducted an electronic and manual literature search using several databases, including the National Library of Medicine (MEDLINE-PubMed), Cochrane Central Register of Controlled Trials (CENTRAL), and EMBASE. Articles were included if they were RCTs involving the interventions regarding the computer-guided impression, placement, and manufacturing process. The outcomes of interest include clinical and patient-reported outcomes and time efficiency. A meta-analysis was conducted to evaluate the time efficiency, pain severity, accuracy of implant placement, and postsurgery marginal bone level., Results: A total of 39 and 25 articles were included in the qualitative and quantitative analysis, respectively. The results of the meta-analysis showed that significantly less time was spent performing the digital impression procedure than the conventional impression (P = .002). In addition, the average adjustment time of the final prosthesis was significantly less than the nondigital fabricated prosthesis (P = .0005). Computer-guided groups reported significantly lower painkiller consumption compared to control groups (P = .03)., Conclusions: Digital impressions and CAD/CAM procedures are time-saving and provide stable and predictable outcomes. Moreover, computer-guided surgery can effectuate an accurate implant placement and less postsurgery discomfort., (Copyright © 2023 Elsevier Inc. All rights reserved.)

Purpose: This in vivo study aims to assess the pink esthetic score in the anterior maxilla after computer-guided immediate implant installation and fully digital immediate temporalization with and without grafting the jumping gap with a mixture of 1:1 autogenous and xenograft particulates., Materials and Methods: Twenty-four patients with non-restorable upper anterior teeth in the aesthetic zone have undergone a traumatic extraction for the non-restorable tooth followed by immediate implant placement using a 3D-printed surgical guide according to prosthetically driven implant placement. The patients were divided into two groups. The study group received the dental implant after grafting the jumping gap with 1:1 autogenous and xenograft particulates, while the control group received the dental implant without grafting the jumping gap. Each patient received a digitally fabricated, immediate, nonfunctional temporary prosthesis. The esthetic outcome was compared between the two groups using the pink esthetic score at implant insertion and after 6 months of follow-up. Statistical comparisons were carried out between the studied groups using the Mann-Whitney U test., Results: Immediately postoperatively, there was no statistically significant difference between the median PES in the two groups (P-value = 0.746). After six months, the study group showed a statistically significantly higher median PES than the control group (P-value = 0.048)., Conclusions: Grafting the jumping distance in the immediate implant protocol helps achieve a better esthetic outcome., Clinical Relevance: The use of immediate guided implant placement along with grafting the jumping gap followed by immediate digital temporalization guarantees a better esthetic outcome while preserving time, cost, and the number of clinical visits., Trial Registration: The study was registered on clinicaltrials.gov with registration number NCT04096209. (19/9/2019)., (© 2023. The Author(s).)

The aim of this report is to present a digital workflow technique to design a customized abutment for provisionalization of an implant immediately placed based on the natural emergence profile of the tooth to be extracted. The workflow involves the combination of intraoral and cone beam computerized tomography scans, from which 3-dimensional reconstructions of soft tissue and alveolar bone, as well as reconstructions of the tooth to be extracted, are obtained and exported as standard tessellation language files. The files are imported to a computer-aided design software, in which a virtual wax-up and custom abutment design are performed considering the natural emergence profile of the patient's tooth prior to extraction. Since the customized abutment is digitally designed, it can also be used as a scan body, to be directly scanned intraorally after soft tissue healing around an interim implant restoration. The custom abutment digitally designed then can be produced by milling zirconia with an optimally chosen color, in accordance with the esthetic needs of the patient.

Aim: To compare and report on the performance of implant-supported fixed dental prostheses (iFDPs) fabricated using additive (AM) or subtractive (SM) manufacturing., Methods: An electronic search was conducted (Medline, Embase, Cochrane Central, Epistemonikos, clinical trials registries) with a focused PICO question: In partially edentulous patients with missing single (or multiple) teeth undergoing dental implant therapy (P), do AM iFDPs (I) compared to SM iFDPs (C) result in improved clinical performance (O)? Included were studies comparing AM to SM iFDPs (randomized clinical trials, prospective/retrospective clinical studies, case series, in vitro studies)., Results: Of 2'184 citations, no clinical study met the inclusion criteria, whereas six in vitro studies proved to be eligible. Due to the lack of clinical studies and considerable heterogeneity across the studies, no meta-analysis could be performed. AM iFDPs were made of zirconia and polymers. For SM iFDPs, zirconia, lithium disilicate, resin-modified ceramics and different types of polymer-based materials were used. Performance was evaluated by assessing marginal and internal discrepancies and mechanical properties (fracture loads, bending moments). Three of the included studies examined the marginal and internal discrepancies of interim or definitive iFDPs, while four examined mechanical properties. Based on marginal and internal discrepancies as well as the mechanical properties of AM and SM iFDPs, the studies revealed inconclusive results., Conclusion: Despite the development of AM and the comprehensive search, there is very limited data available on the performance of AM iFDPs and their comparison to SM techniques. Therefore, the clinical performance of iFDPs by AM remains to be elucidated., (© 2023 The Authors. Clinical Oral Implants Research published by John Wiley & Sons Ltd.)

Background: A fixed screw-retained full-arch restoration supported by four implants is a popular treatment option for edentulous arches. Optimal alignment of implants is quite challenging in extremely atrophied edentulous cases, and a small amount of deviation is expected during guided surgery. This study aimed to compare implant accuracy among edentulous jaws with various levels of atrophy., Methods: Five separate copies of each Cawood and Howell model (III-V) were produced for the maxilla and mandible. A total of 120 implants (30 models). The implant accuracy was assessed based on angular deviations at the base (angle, 3D offset, distal, vestibular, and apical) and tip (3D offset, distal, vestibular, and apical)., Results: The atrophy level of the jaws had a statistically significant effect on deviation; implants showed greater deviation from the planned location as the atrophy level increased., Conclusion: Given that implant deviation increased with the degree of atrophy, a greater safety margin from important anatomical structures is recommended when planning implant location for guided surgery in Cawood and Howell V cases., (© 2023. BioMed Central Ltd., part of Springer Nature.)

Purpose: This study was conducted to evaluate the clinical peri-implant soft tissue changes during the first year after occlusal loading and the ridge base relation after 3 years for mandibular computer-aided design and computer-aided manufacturing (CAD-CAM) screw-retained implant-supported hybrid prosthesis of polyetheretherketone (PEEK) framework utilized with All-on-Four treatment concept., Materials and Methods: Sixteen completely edentulous patients were rehabilitated by four implants following the All-on-Four protocol. After 3 months, the definitive prosthesis was constructed to be a screw-retained CAD-CAM milled framework from the modified PEEK (BioHPP), bonded to polymethylmethacrylate teeth and a pink shaded indirect light-polymerized nanofilled composite resin imitating the soft tissues. Peri-implant soft tissue changes regarding plaque, bleeding, gingival scores, and probing depth were evaluated at prosthesis insertion (T0), 6 months (T1), and 12 months (T2) after insertion. Also, monitoring of the ridge base relation was performed using cone beam computed tomography at time of insertion (T0), and 1 year (T1), 2 years (T2), and 3 years (T3) after mandibular fixed detachable All-on-Four framework insertion. Using Shapiro-Wilk tests using SPSS ® software version 22 (SPSS Inc., Chicago, IL), all clinical data were nonparametric, while the ridge base relation data were parametric., Results: There were statistically significant differences regarding a plaque, gingival, and bleeding scores for all implants with the advancement of time. However, there was a statistically insignificant difference regarding probing depth in the posterior implants (p = 0.581). Regarding ridge base relation, there was a significant difference between observation times only in the anterior ridge area in between the two anterior implants (p = 0.011)., Conclusions: Within the limitations of the study, the full-arch PEEK framework of fixed-detachable, hybrid prosthesis used with the All-on-Four concept for rehabilitation of mandibular edentulous arches is an acceptable treatment approach. Based on the stable ridge base relation posteriorly found in this study, less stress is distributed to the underlining bone due to the shock-absorbing ability of PEEK. Special considerations for frequent soft tissue follow-up and regular maintenance of oral hygiene measures are recommended., (© 2022 by the American College of Prosthodontists.)

Purpose: We present our experience of titanium-milled two-piece patient-specific implants (PSIs) for primary reconstructions of extensive orbital floor and medial wall fractures (EOFMFs) and evaluate their postoperative functional and aesthetic outcomes in relation to commercially available implants., Methods: We included all patients with primary reconstructions (< 22 days from injury) of EOFMFs treated in our department between January 2011 and October 2020. Extensive orbital floor and medial wall fracture was defined as involvement of orbital floor, medial wall and maxilloethmoidal junction; a fracture defect 5 mm or more; defect size more than a third of both inferior and medial walls; and Jaquiéry classification III or more. Patient characteristics, details of fracture defects and surgeries, postoperative outcomes and implant positions were retrospectively evaluated and compared between study groups., Results: Nineteen patients were included: 5 with two-piece PSIs and 14 with commercial implants. Implant position was good in 4/5 patients with two-piece PSIs and 2/14 with commercial implants. Revision surgery, globe malposition (GMP) > 2 mm, significant diplopia and poor implant position were more frequent in patients with commercial implants than two-piece PSIs. None of the patients with a good overall implant position had any significant postoperative symptoms., Conclusion: Extensive orbital fracture reconstructions are somewhat rare, and surgical treatment is associated with a high rate of complications and postoperative symptoms. Titanium-milled two-piece PSIs are well suited for primary reconstructions of EOFMFs, as they lead to more precise reconstructions and fewer postoperative symptoms than commercially available implants., (© 2022. The Author(s).)

Purpose: The aim of this study was to evaluate the mechanical behavior of an implant-supported crown made using computer-aided design and computer-aided manufacturing (CAD-CAM) resin composite (RC) blocks in the posterior region., Material and Methods: Four commercially available CAD-CAM RC blocks were used in this study: Cerasmart 300 (CS300; GC, Tokyo, Japan), Katana Avencia P Block (KAP; Kuraray Noritake Dental, Niigata, Japan); KZR HR3 Gamma Theta (HR3; Yamakin, Osaka, Japan), and Estelite P block (ESP; Tokuyama Dental, Tokyo, Japan). Katana Zirconia STML (ST; Kuraray Noritake Dental) was used as the control group. The elastic moduli of each material were determined by a three-point bending test. After the CAD models were designed, two different loading scenarios (oblique, vertical) were created. 3D finite element analysis was conducted with the prepared models., Results: The elastic modulus of the material utilized for the implant restorations did not cause any change in the stresses transmitted to the implant or peripheral bone. An important difference was detected in the abutment-crown junction area. The minimum von Mises value at the abutment-crown interface was obtained in ST, which has the closest elastic modulus to the titanium abutment., Conclusions: The 3D finite element model designed in this study was used to demonstrate that implant-supported crowns fabricated with four different CAD-CAM RCs showed no critical stress concentrations in the bone or implant under all loading conditions. These results suggest that CAD-CAM RC blocks could be used as an alternative material for implant-supported restorations in the posterior region in terms of stress distribution., (© 2022 by the American College of Prosthodontists.)

Purpose: Implants placed at variable depths may vary the amount of visible scannable surface of a scan body. Intraoral scanner technology uses advanced optical principles to record the surface of the scan body to accurately capture the implant position. The purpose of this study is to investigate the effect implant placement depth has on the accuracy of digital implant impressions using an intraoral scanner., Materials and Methods: A partially edentulous gypsum master model was fabricated to allow the positioning of a single implant analog at different depths. Four groups were created based on the planned implant depths of 7, 6, 3, and 0 mm and corresponding visibility of the scan body at 2, 3, 6, and 9 mm. The model was digitized with a laboratory scanner for the reference scan and with an intraoral scanner to generate 15 test scans per group, with a total of 60 scans. The test scans were superimposed onto the reference scan using the best fit algorithm to analyze and measure the positional (dXYZ) and angular deviation (d⍬) of the scan body using three-dimensional metrology software. Statistical analysis was performed using a one-way ANOVA and pairwise comparison was done with a Tukey-Kramer HSD test (α = 0.05)., Results: The one-way ANOVA of the groups for the dXYZ and dθ parameters was statistically significant (F 3,56 = 11.45, p < 0.001, F 3,56 = 24.04, p < 0.001). Group D (9 mm) showed the least positional deviation at 38.41 μm (95% CI 30.26; 46.56) and the least angular deviation of 0.17° (95% CI 0.12; 0.21). Group A (2 mm) showed the greatest positional deviation of 77.17 μm (95% CI 65.23; 89.11) and greatest angular deviation of 0.84° (95% CI 0.65; 1.03). The positional and angular deviation increased with increased implant depth., Conclusions: The accuracy of digital impressions is influenced by the implant depth and the amount of visibility of the scan body. The trueness and precision are highest when the implant is placed at 0 mm depth with complete visibility of the scan body and decreases with subgingival implant placement., (© 2022 by the American College of Prosthodontists.)

Computerised surgical planning (CSP) and computer-aided design and manufacturing (CAD/CAM) have been demonstrated to increase surgical accuracy and reduce operative time in free flap mandibular reconstruction, but evidence is lacking as to their impact on patient-centred outcomes. Implant-supported dental prostheses, however, have been associated with improved quality of life outcomes following free flap mandibular reconstruction. We aim to review reported patient-centred outcomes in mandibular reconstruction with CSP and CAD/CAM and determine whether use of these technologies is associated with higher rates of dental implant placement following free flap mandibular reconstruction. On December 20, 2020, a systematic review and meta-analysis were conducted according to PRISMA guidelines for studies reporting quality of life, functional outcomes, and rates of dental implant placement in computer-aided free flap mandibular reconstruction. A random-effects meta-analysis was performed to compare dental implant placement rates between surgeries using CSP and those using conventional freehand techniques. A total of 767 articles were screened. Nine articles reporting patient-centred outcomes and 16 articles reporting dental implant outcomes were reviewed. Of those reporting dental implant outcomes, five articles, representing a total of 302 cases, were included in the meta-analysis. Use of CSP was associated with a significant increase in the likelihood of dental implant placement, with an odds ratio of 2.70 (95% CI 1.52 to 4.79, p = 0.0007). Standardised reporting methods and controlled studies are needed to further investigate the impact of CSP and CAD/CAM technologies on functional outcomes and patient-reported quality of life in free flap mandibular reconstruction. Use of CSP and CAD/CAM technologies is associated with higher rates of dental implant placement in patients undergoing free flap mandibular reconstruction when compared to conventional freehand techniques., (Copyright © 2022 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.)

Purpose: To investigate the error accumulation and distribution through various stages of the digital workflow for complete-arch implant-supported framework fabrication., Materials and Methods: A resin model of edentulous maxilla with 6 dental implants was scanned using an intraoral scanner for 10 times (Complete-digital group). Ten conventional gypsum casts were made and digitized by a laboratory scanner (Analogue-digital group). Five implant frameworks were designed and milled using CAD-CAM technique for each workflow. Inter-implant distances and angles of the resin model (reference) and frameworks were measured by a coordinate measuring machine, while the scans and virtual frameworks were examined by an inspection software. Effect of type of workflow and the individual stage on the accuracy of the frameworks were analysed by Two-way ANOVA., Results: The expanded uncertainty of both workflows was ~150 μm and ~ 0.8°. The accuracy of the CAD stage was the highest. In the complete-digital workflow, the greatest distortion was found in the data acquisition stage, while in the analogue-digital workflow, it was found in the CAM stage. Compared with the analogue-digital group, the complete-digital group showed a significant higher precision in the first quadrant, but lower trueness in the second quadrant in data acquisition, and a significantly lower precision in the second quadrant at the CAD stage., Conclusions: Linear distortions of the complete-digital and analogue-digital workflows were clinically acceptable, while angular distortions were not. Distortions were generally derived from data acquisition and CAM stage. The CAD precision depended on the distortions derived from data acquisition. The complete-digital workflow was not as accurate as the analogue-digital in complete-arch implant rehabilitation., (© 2022 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.)

Purpose: To review the most up to date scientific evidence concerning the technical implications, soft tissue biocompatibility, and clinical applications derived from the use of titanium nitride hard thin film coatings on titanium alloy implant abutments., Materials and Methods: A review was performed to answer the following focused question: "What is the clinical reliability of nitride coated titanium alloy abutments?". A MEDLINE search between 1980 and 2021 was performed for investigations pertaining to the clinical use of nitride coated titanium alloy implant abutments (TiN) in case reports, case series, and short- and long-term non/randomized controlled clinical trials. Literature analysis led to addition evaluation of research related to the technical and biological aspects, as well as the physicochemical characteristics of TiN hard thin film coatings and their impact on titanium abutment biocompatibility, mechanical properties, macroscopic surface topography, and optical properties. Therefore, preclinical data from biomechanical and in vitro investigations were also considered as inclusion criteria., Results: The limited number of clinical investigations published made a systematic review and meta-analysis not possible, therefore a narrative review was conducted. TiN coatings have been applied to dental materials and instruments to improve their clinical longevity. Implant abutments are coated with titanium nitride to mask the titanium oxide surface and enhance its surface characteristics providing the TiN abutment surface with a low friction coefficient and a very high chemical inertness. TiN coating is suggested to reduce early bacterial colonization and biofilm formation and enhance fibroblast cell proliferation, attachment and adhesion when compared to Ti controls. Additionally, studies indicate that hard thin film coatings enhance the mechanical properties (hardness and wear resistance) of titanium alloy and appears as a yellow color when deposited on the titanium alloy substrate. To date, clinical investigations show that nitride coated titanium abutments provide promising short-term clinical outcomes., Conclusions: Published research on nitride-coated abutments is still limited, however, the available biomedical research, mechanical engineering tests, in vitro investigations, and short-term clinical trials have, to date, reported promising mechanical, biological, and esthetic outcomes., (© 2021 by the American College of Prosthodontists.)

This clinical report focuses on the challenges and solutions for a child subjected to craniofacial trauma from a wild hyena biting off his nose and anterior maxilla. Unique considerations in prosthodontics and biomedical engineering were required based on future craniofacial growth and development of the child. The physical requirement of a maximum retentive prosthesis for an active, athletic child required unique engineering designs and executions. The sequence of treatment and prosthesis fabrication are detailed. The patient has been followed for 9 years without physiologic complications and only minor prosthodontic complications., (© 2022 by the American College of Prosthodontists.)

Objectives: To compare 2 implant scan bodies with different geometry on the accuracy of the virtual alignment process in the digital workflow., Materials and Methods: A master model of the edentulous maxilla with 6 implants and multiunit abutments (MUA) inserted was fabricated. Six dome-shaped and cuboidal scan bodies were mounted on the MUAs, respectively, and consecutively scanned by a laboratory scanner 10 times. The original scans were imported to a dental-specific CAD software and virtually aligned with the default CAD model in the implant library. Thus, 10 aligned models were created. Both the original scans and the aligned models were evaluated by an inspection software for deviation of the scan body surfaces, the centroids of scan body and MUA, the scan body center-axis, and the inter-MUA distances/angles. The two-sample T-test/Mann-Whitney U test were used to analyze the data with the level of significance set at 0.05., Results: The cuboidal group showed significant greater deviations of the model surface (13.9 µm vs. 10.7 µm) and the MUA centroids (31.7 µm vs. 22.8 µm) but smaller deviation of the inter-MUA angle (0.047° vs. 0.070°) than those of the dome-shaped group (p < .05). No significant differences in the deviation of scan body centroids, center-axis, and the inter-MUA distances between the 2 groups were found., Conclusions: Virtual alignment of implant scan body affected the accuracy of the digital workflow for complete-arch implant-supported prostheses (up to ~30 µm/0.09°). Different geometries of the implant scan body could also influence the transfer accuracy in the CAD process., (© 2022 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.)

Static computer assisted implant surgery (s-CAIS) is an integral part of the digital workflow in implant dentistry and provides the link between the virtual planning environment and surgical field. The accuracy of s-CAIS is influenced by many cumulative factors including the fit of the template which is related to the manufacturing process. This critical review provides an overview of the current research on additively manufactured surgical implant guides., (© 2022 by the American College of Prosthodontists.)

Background: Sandwich osteotomy technique (Inlay bone grafting) is considered as a highly reliable procedure for vertical bone augmentation in the maxillary anterior esthetic zone. The aim of this study was to compare vertical bone gain and palatal tipping using computer-guided inlay technique versus the conventional technique., Material and Methods: This was a randomized clinical trial including 12 patients who were randomly divided into two groups: sandwich osteotomy with simultaneous implant placement at the anterior maxillary esthetic zone (six patients) using patient-specific guides (PSGs) in the study group versus conventional technique (six patients). In the control group, free-hand sandwich osteotomy was done, while in the study group all the procedures were performed with two sequential PSGs with cutting slits, guiding holes, and implant sleeves. Radiographic assessment included measurements of linear changes in the vertical dimensions of the labial plate of bone and palatal tipping on cross-sectional cuts of cone-beam computed tomography using special software., Results: All the procedures were uneventful except one case of the study group showed a cracked bony segment that did not affect the final outcome. Radiographic results showed comparable bone gain in both groups with no statistical significance difference (study group 4.4 mm, control group 3.9 mm). To the contrary, the computer-guided approach significantly reduced the palatal tipping to 0.4 mm compared to 2.1 mm in the conventional group, and there was a statistically significant difference between the two groups (p-value <0.001)., Conclusion: Sandwich osteotomy using PSGs appears to be efficient and showed promising results regarding improving the palatal tipping compared to the free-hand technique., (© 2021 Wiley Periodicals LLC.)

Purpose: To investigate the trueness and marginal fit of computer-aided design-computer-aided manufactured (CAD-CAM) complete-arch implant-supported screw-retained fixed prosthesis (CAISFP) made of polyetheretherketone (PEEK), polyetherketoneketone (PEKK) and titanium (Ti) MATERIAL AND METHODS: A typodont model with four implants, their multiunit abutments (MUAs), and MUA scanbodies were digitized by using a laboratory scanner. The generated CAD was used to mill CAISFP frameworks in Ti, PEEK, or PEKK (each n = 10). The frameworks were digitized with an industrial light scanner to superimpose resulting standard tessellation language (STL) file with the CAD file. Deviations at five points at the abutment-framework interface of each of the four abutment sites (1:left first molar, 2:left canine, 3:right canine, 4:right first molar sites) were calculated (trueness). Marginal gaps were measured using the triple scan technique. A nonparametric repeated measures ANOVA by Brunner and Puri with factors being abutment location and material was performed to assess the mean deviations for trueness and mean marginal gaps, followed by Mann-Whitney or exact Wilcoxon Signed-Rank tests (alpha=.05)., Results: Material type significantly affected the trueness (p<0.0001). PEEK had the lowest deviations (0.039 +/-0.01mm) followed by PEKK (0,049 +/-0.009mm), and Ti (0.074 +/-0.011mm). For marginal gaps, only abutment location's effect was significant (p = 0.003). Within PEKK, gaps at abutment 4 were significantly larger, compared with abutments 2 (p = 0.04) and 3 (p = 0.02)., Conclusions: The trueness of PEEK, PEKK, and Ti frameworks was different after milled. PEEK had the highest trueness. However, the marginal fit of the frameworks was similar and smaller than 90 µm in average., Clinical Relevance: PEEK, PEKK, and Ti complete-arch frameworks had clinically acceptable gaps and may therefore be recommended when their fit is considered. Higher trueness after milling did not result in better marginal fit., (Copyright © 2021. Published by Elsevier Ltd.)

Background: Ridge splitting technique is considered one of the successful horizontal bone augmentation procedures especially for the maxillary bone, the aim of this study was to compare marginal bone loss using a novel ridge splitting protocol versus the conventional technique., Material & Methods: This was a randomized clinical trial including 20 patients who were randomly assigned to ridge splitting with simultaneous implant placement at the anterior maxillary aesthetic zone (10 patients, 29 dental implant) using patient specific guides (PSGs) or conventional technique (10 patients, 29 dental implant). In the control group free hand ridge splitting was done, while in the study group all the splitting and drilling procedures were done through specific slits and sleeves at the patient specific guides. Radiographic Assessment included measurements of linear changes in the vertical dimensions of the labial plate of bone on cross sectional cuts of computed tomography (CBCT) using mimics software., Results: Wound healing was uneventful for all the patients except one patient in the control group that showed bad split and another showed buccal fenestration. The study group showed lower bone loss (1.38 ± 0.61 mm) compared to the control group (2.42 ± 0.63 mm), with statistical significance difference (P value = 0.001). The loss percentage also was higher in the study group (10.99 ± 4.76%) compared to the control group (19.12 ± 4.53%), and there was statistical significance difference between the two groups (P value = 0.001)., Conclusion: Ridge splitting using PSGs appear to be efficient and promising than the free hand technique., (© 2021 Wiley Periodicals LLC.)

Objectives: To present the results of guided bone regeneration (GBR) of atrophic edentulous ridges with customized CAD/CAM titanium meshes., Material and Methods: Forty-one patients, presenting with 53 atrophic sites, were enrolled between 2018 and 2019. GBR was obtained with titanium meshes filled with autogenous bone chips and bovine bone mineral (BBM). After a mean of 7 months (range: 5-12 months), meshes were removed and 106 implants placed. After a mean of 3.5 months (range: 2-5 months), implants were uncovered and prosthetic restorations started. The outcomes were vertical and horizontal bone augmentation changes, biological complications and implant survival., Results: Out of 53 sites, 11 underwent mesh exposure: eight of them were followed by uneventful integration of the graft, while three by partial bone loss. The mean vertical and horizontal bone gain after reconstruction was 4.78 ± 1.88 mm (range 1.00-8.90 mm) and 6.35 ± 2.10 mm (range 2.14-11.48 mm), respectively. At the time of implant placement, mean changes of initial bone gain were -0.39 ± 0.64 mm (range -3.1 to + 0.80 mm) and -0.49 ± 0.83 mm (range -3.7 to +0.4 mm), in the vertical and horizontal dimensions, respectively. Reduction of bone volume was significantly higher (p < .001 for both dimensions) in the exposed sites. The mean follow-up of implants after loading was 10.6 ± 6.5 months (range: 2-26 months). The survival rate of implants was 100%., Conclusion: Customized titanium meshes can represent a reliable tool for GBR of severely atrophic sites, with simplification of the surgical phases., (© 2021 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.)

Objective: CAD-CAM has dramatically advanced dental restorative procedures to include implant-supported crowns. The purpose of this study was to compare the fracture resistance following mechanical loading and thermocycling of various screw-retained and cement-retained ceramic and polymethylmethacrylate material combinations using the TiBase abutment compared to PFM implant-supported crowns., Overview: Twelve implant restorations were fabricated for each of eight groups. Three groups were screw-retained and five groups were cement-retained implant restorations. The ceramic and polymethylmethacrylate restorations were fabricated on the TiBase abutment while the PFM restorations were fabricated on an UCLA abutment. Data were analyzed with a one way Analysis of Variance and Tukey's post-hoc test to evaluate the effect of abutment and crown type on fracture load (alpha = 0.05). A significant difference was found in the maximum fracture load between groups (P < 0.001)., Conclusions: The screw-retained implant restorations demonstrated higher fracture loads than their cement-retained counterparts. The TiBase abutment compared favorably to the UCLA abutment., Clinical Significance: The TiBase abutment is a titanium insert which combines the esthetics of a ceramic abutment with the mechanical properties of a titanium abutment and should be considered a viable clinical alternative to the conventional implant-supported PFM crown based on theses in vitro results and in context of in vivo studies. The lithium disilicate hybrid abutment/crown implant-supported restoration utilizing the TiBase abutment may be an ideal clinical choice due to simplicity, single appointment CAD-CAM, and esthetics., (© 2020 Wiley Periodicals LLC.)

Reconstruction of mandibular defects after trauma or tumor resection is one of the most challenging problems facing maxillofacial surgeons. Historically, various autografts and alloplastic materials have been used in the reconstruction of these types of defects. The use of individualized designed biomaterials has opened new possibilities in reconstructive surgery, and now, it is possible to use the patient's computed tomography (CT) to construct patient-specific implants (PSIs). A case of a large mandibular tumor resection and reconstruction of the defect using a customized 3D-printed titanium implant is described. The treatment had excellent postoperative esthetic and functional results without complications. CONCLUSION: Because titanium implants are customizable, easily workable especially with help of 3D virtual planning techniques, bioinert, and nonporous, they represent an ideal alloplastic material for mandibular reconstruction.

Background: The load-to-failure performance of computer-assisted design and computer-assisted manufacturing (CAD-CAM) high performance polymers (HPP) and new generation cubic zirconia (Zir) material when used with titanium (Ti) bases for implant-supported fixed prostheses with cantilevers is unknown., Purpose: To evaluate the load-to-failure performance of different CAD-CAM fabricated HPP and a new generation cubic Zir in a cantilevered situation when used with Ti bases., Materials and Methods: Five specimens with a Ti base and five specimens without Ti bases were fabricated from seven different CAD-CAM HPPs (100% PEEK [J and CP], 80% PEEK with 20% filler [BRE], 80% PEKK with 20% filler [PK], ceramic reinforced PEEK [ZZ], interlaced fiberglass and resin [TR], fiber-composite material [T]). Five specimens with Ti base and two specimens without Ti base were prepared from a new generation cubic Zir (DD) and a 3Y-TZP Zir (FZR) as the control group (N = 84). All specimens (8 × 7 × 30 mm) were stabilized using a clamp attached to the first 20 mm of each specimen for a 10 mm cantilever. Static loading was applied vertically on the cantilever and the maximum load-to-failure values (N) were analyzed using a two-way ANOVA and t-test (alpha = .05)., Results: HPP and Zir specimens without Ti bases had significantly higher load-to-failure values than Ti based ones in all groups (P < .05). PK with Ti base had significantly lower load-to-failure values than other materials (P < .001). FZR showed significantly higher load-to-failure values than all HPPs and DD (P < .001)., Conclusions: Load-to-failure values of HPPs and Zir were lower when Ti bases were used. New generation cubic Zir and all HPPs had lower load-to-failure values than FZR. HPPs performance varied among tested materials. PEKK with Ti base had the lowest load-to-failure value., (© 2019 Wiley Periodicals, Inc.)

The purpose of this in vitro study was to measure the vertical, positive-horizontal, and negative-horizontal misfit (VM, PHM, and NHM, respectively) of the zirconia three-element prosthetic framework, fabricated using different methods, and compare them with conventional fabrication methods (lost-wax casting). Furthermore, this study aimed to evaluate the influence of the misfit values on the biomechanical behavior of the 3-unit fixed prosthetic frameworks using three-dimensional finite element analysis (3D-FEA). Forty frameworks (n = 10) were fabricated as follow: G1, Cerec Bluecam; G2, iTero; G3, 3Series; and G4, conventional method. The samples were randomized to measure marginal misfit using a high-precision three-dimensional (3D)-optical microscope. The results were submitted to analysis of variance (ANOVA), with the significance level set at 5%. The mean VM values of each group were used in creating the models by 3D-FEA with the misfit found in optical microscopy. The programs used were the InVesalius, Rhinoceros, SolidWorks, FEMAP and NEiNastran. The von Mises map was plotted for each model. The G4 showed the lowest mean VM value (16.73 μm), followed by G3 (20.71 μm), G2 (21.01 μm), and G1 (41.77 μm) (p < 0.001). G2 was more accurate than G1 (p < 0.05) and similar to G3 (p = 0.319). For PHM, G4 was the most accurate and did not present overextended values. With regard to NHM, the computer-aided design and computer-aided manufacturing (CAD-CAM) systems were more accurate (-61.91 μm) than G4 (-95.36 μm) (p = 0.014). In biomechanical analysis, stress concentration caused by oblique loading is greater than caused by axial loading. In axial loading, G4 was the most favorable while G1 was the least favorable, biomechanically, in oblique loading, similar stress patterns were observed in all the models. The prosthetic screw was the most overloaded structure, but the material did not influence the stress distribution. The misfit prostheses showed a greater degree of stress than the controls (without misfit). The manufacturing method influenced the marginal misfit of the frameworks, with the conventional method being the most accurate and the Cerec Bluecam System (closed system) the least accurate. Biomechanically, fitting prostheses were more favorable than misfit prostheses., (Copyright © 2019. Published by Elsevier B.V.)

Objectives: This observational clinical study evaluated the patient satisfaction and the clinical outcomes of edentulous arches rehabilitated with overdentures retained by CAD-CAM milled titanium bars., Materials and Methods: Edentulous patients were treated with a full-arch removable overdenture anchored on two milled bars based on a friction retention system. Patient satisfaction was tested using the validated Oral Health Impact Profile (OHIP-14) questionnaire at the pre- and post-treatment visits, up to two years after prosthesis delivery (possible score range: 0-56. Best: 0). The prosthodontist satisfaction was also assessed through a designed questionnaire (best possible range 0-4. Best:0). Radiographic and clinical examinations were performed at baseline and after 2 years of function. Implant and prostheses complications were recorded., Results: Forty (25 mandible) edentulous patients, mean age 69 ± 9.5 (SD) (52% males, 10% smokers), were treated with a total of 185 implants. The mean difference between pre- and post-treatment OHIP-14 score was 20.6 ± 8.0 (P < 0.0001) showing a high level of satisfaction for aesthetics, functional and psychological outcomes. This perception was not influenced by patient's age or gender. The clinicians' mean score was 3.4 ± 4.0. There was a marginal bone level (MBL) gain of 0.02 ± 0.22 mm between the two time points. Minor complications were reported in five patients., Conclusions: This procedure may lead to satisfaction regarding aesthetics and mastication function. One of the most relevant aspects is the versatility, which allows selection of the most suitable treatment option according to patient needs. The prosthodontist satisfaction questionnaire showed that this procedure met the clinical expectations., (© 2019 John Wiley & Sons Ltd.)

Purpose: This study describes a method for measuring the accuracy of the virtual impression., Methods: In vitro measurements according to a metrological approach were based on (1) use of an opto-mechanical coordinate measuring machine to acquire 3D points from a master model, (2) the mathematical reconstruction of regular geometric features (planes, cylinders, points) from 3D points or an STL file, and (3) consistent definition and evaluation of position and distance errors describing scanning inaccuracies. Two expert and two inexpert operators each made five impressions. The 3D position error, with its relevant X, Y, and Z components, the mean 3D position error of each scanbody, and the intra-scanbody distance error were measured using the analysis of variance and the Sheffe's test for multiple comparison., Results: Statistically significant differences in the accuracy of the impression were observed among the operators for each scanbody, despite the good reliability (Cronbach's [Formula: see text] = 0.897). The mean 3D position error of the digital impression was between 0.041 ± 0.023 mm and 0.082 ± 0.030 mm., Conclusions: Within the limitations of this in vitro study, which was performed using a single commercial system for preparing digital impressions and one test configuration, the data showed that the digital impressions had a level of accuracy comparable to that reported in other studies, and which was acceptable for clinical and technological applications. The distance between the individual positions (#36 to #46) of the scanbody influenced the magnitude of the error. The position error generated by the intraoral scanner was dependent on the length of the arch scanned. Operator skill and experience may influence the accuracy of the impression.

Objectives: To determine the clinical and patient-reported outcomes of bi-layered, all-ceramic posterior single crowns (SCs) supported by zirconia implants in an uncontrolled, prospective, multicenter study., Methods: In two centers, 60 patients received 71 one-piece zirconia oral implants to be restored with either SCs (n=49) or three-unit fixed dental prostheses (n=11). Of these patients, 45 implants were restored with all-ceramic, zirconia-based posterior SCs (one per patient). Survival rates of implants and reconstructions were assessed, and technical success was evaluated according to modified U.S. Public Health Service (USPHS) criteria. Furthermore, patient-reported outcome measures (PROMs) were assessed by applying visual analog scales (VAS). Kaplan-Meier (KM) plots and log-rank tests were used for success/survival analyses. The Wilcoxon matched-pairs signed-rank test was used to evaluate time effects on response variables (PROMs, USPHS criteria)., Results: Forty patients with 40 SCs could be evaluated after 36.7±1.2months. No SC was replaced, resulting in 100% survival. The KM success estimate was 87.5% (two chippings, one restoration margin, and one contour were rated Charlie). In general, the incidence of chipping (p=.0005) and occlusal roughness (p=.0003) was frequent. Compared with the pre-treatment patient surveys (67-93%), all surveys at prosthetic delivery except for speech (p=.139) showed significantly improved VAS scores (81-94%; p<.0001). Thereafter, no decrease in satisfaction could be observed over time until the 3-year follow-up (86-93%; p≥.390)., Conclusion: Veneered, zirconia-based SCs supported by zirconia implants satisfied patients' needs highly. However, significant incidence of chipping and roughness of the veneering ceramic may compromise the clinical long-term outcome for this indication., Clinical Significance: Posterior, zirconia-based SCs supported by zirconia oral implants entirely survived the follow-up period of 3 years, but two major chippings, one a significant marginal opening and one pronounced over-contouring, resulted in a reduced KM success estimate of 87.5% after 36 months of observation., (Copyright © 2017 Elsevier Ltd. All rights reserved.)

Objective: The aim of this study was to determine the success and survival rate of all-ceramic bi-layered implant-supported three-unit fixed dental prostheses (IS-FDPs) 3 years after implant placement., Material and Methods: Thirteen patients (seven males, six females; age: 41-78 years) received two one-piece ceramic implants (alumina-toughened zirconia) each in the region of the premolars or the first molar and were finally restored with adhesively cemented bi-layered zirconia-based IS-FDPs (3 in the maxilla, 10 in the mandible) composed of CAD/CAM-fabricated zirconia frameworks pressed-over with fluor-apatite glass-ceramic ingots. At prosthetic delivery and the follow-ups after 1, 2 and 3 years, the restorations were evaluated using modified United States Public Health Service (USPHS) criteria. Restorations with minor veneer chippings, a small-area occlusal roughness, slightly soundable restoration margins, minimal contour deficiencies and tolerable color deviations were regarded as success. In case of more distinct defects that could, however, be repaired to a clinically acceptable level, IS-FDPs were regarded as surviving. Kaplan-Meier plots were used for the success/survival analyses. To verify an impact on subjective patients' perceptions, satisfaction was evaluated by visual analog scales (VAS)., Results: All patients were seen 3 years after implant installation. No IS-FDP had to be replaced, resulting in 100% survival after a mean observation period of 29.5 months (median: 30.7). At the 3-year follow-up, 7/13 IS-FDPs showed a veneer chipping, 13/13 an occlusal roughness and 12/13 minimal deficiencies of contour/color. Since six restorations showed a major chipping and/or a major occlusal roughness, the Kaplan-Meier success rate was 53.8%. However, patients' significantly improved perceptions of function, esthetics, sense, and speech at prosthetic delivery remained stable over time., Conclusion: Bi-layered zirconia/fluor-apatite IS-FDPs entirely survived the observation period but showed a high frequency of technical complications. Nevertheless, the treatment highly satisfied patients' expectations., (© 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.)

Objective: Given the significant role of retention in the long‐term success of implant‐supported prostheses, this study aimed to compare the retentive strength of three‐unit implant‐supported frameworks manufactured using the conventional, subtractive milling, and 3D printing methods. Materials and Methods: In this in vitro study, two fixture analogs were placed in the mandibular right first premolar and first molar region of a Dentiform model, and two prefabricated abutments were secured in the fixture analogs. A total of 27 three‐unit frameworks were fabricated utilizing wax patterns prepared through conventional, milling, and 3D printing techniques (n = 9 per group). The frameworks were cemented with zinc oxide eugenol and subjected to thermocycling. The retentive strength of each specimen was evaluated through a pull‐out test conducted with a universal testing machine. The data were analysed using one‐way ANOVA and Tukey's post hoc test (p < 0.05). Results: The three groups were found to be significantly different (p = 0.01). While the 3D printing and milling groups were not significantly different (p = 0.99), they yielded significantly higher retentive strength compare to the conventional group (p = 0.02 for 3D printing and p = 0.03 for milling group). Conclusion: The utilization of 3D printing and milling technique for wax pattern preparation significantly increased the retention of the implant‐supported framework, with no statistically significant difference between the two methods. [ABSTRACT FROM AUTHOR]

Objectives: This study aimed to assess the influence of translucent monolithic versus bilayered crowns and whether the use of a CoCr base abutments affects the fatigue and fracture resistance of screwed implant‐supported single crowns with external connections under mechanical cycling. Materials and Methods: Fifty specimens were divided into groups: (1) metal–ceramic (MC) crown, (2) veneered zirconia crown (Zr), (3) veneered zirconia crown with a CoCr base abutment (ZrB), (4) monolithic translucent zirconia crown (MZr), and (5) monolithic translucent zirconia crown with a CoCr base abutment (MZrB). Specimens underwent mechanical cycling (5 × 106 cycles; 150 N) evaluating fatigue resistance (number of failures) and those that failed were subsequently subjected to fractographic analyses (stereomicroscope and scanning electron microscope) to evaluate failure location and area, and maximum fracture load was also measured. Results: The failure‐related survival rate (100%) and maximum fracture resistance of the MZrB were significantly higher than those of MC and Zr (50%; p < 0.05). There were no significant differences in the failure rate and fracture resistance when a CoCr base abutment was used or not in the translucent monolithic Zr groups (p > 0.05;MZrB vs. MZr). Failure location, with MC crowns' fractures, noted at the screw area (p = 0.043), while all‐ceramic crowns were mostly in the cuspid and to failure area, the Zr group had the largest mean (15.55 ± 9.17 mm2) among the groups, significant difference only when compared with MC (1.62 ± 0.81 mm2) (p = 0.025). Conclusions: Translucent monolithic zirconia crowns exhibited significantly higher fatigue and fracture resistance compared with conventional MC and bilayered crowns. Clinical Significance: The appropriate choice of material and manufacturing technique is crucial for predicting the higher clinical performance of single crowns. Enhanced mechanical resistance in terms of fatigue and fracture resistance can be achieved by replacing MC and bilayered restorations with computer‐aided design and computer‐aided manufacturing monolithic zirconia. [ABSTRACT FROM AUTHOR]

The aim of this in vitro study is to compare the performance of digital and conventional methods in the manufacture of single copings in terms of the internal and marginal fit. Twenty‐four prefabricated titanium Cone Morse Exact abutments of the lateral anatomical type were used to manufacture 24 lithium disilicate copings in the CAD‐CAM Ceramill (n = 12) and heat‐press (n = 12) systems. The copings were cemented using a self‐adhesive resin cement (RelyX U‐200; 3M ESPE) and then cut vertically. The cement line was photographed using an optical microscope at ×100 and ×200 magnification and then the internal and marginal regions were measured. The mean values of fits, for the CAD‐CAM and heat‐press techniques, respectively, were (μm): angular regions, 81.8 and 75.3; linear regions, 63.1 and 60.1; incisal regions, 171.1 and 114.7; marginal discrepancy, 74.1 and 75.2; and absolute marginal discrepancy, 99.5 and 96.2. MANOVA test showed that there is an effect of the techniques on the regions (p <.05). The effects of laboratories and the interaction between laboratories and techniques on the regions were not statistically significant (p >.05). The techniques evaluated presented clinically acceptable results for the marginal fit. However, the conventional method performed better for the internal fit. Research Highlights: Scientific evidence regarding the methods of making prosthesis can help the dental professional in decision‐making. Digital and conventional methods is both good in the manufacture of single copings in terms of the internal and marginal fit. [ABSTRACT FROM AUTHOR]

Background: Marginal misfit and surface roughness of customized implant abutments is critical for restorative success. However, little is known about the comparison of misfit and surface roughness of CAD-CAM Zirconium oxide (ZrO), selective laser melting (SLM) Cobalt Chrome (CoCr) and preformed abutments. The aim of the study is to investigate the relation of misfit and micro-roughness of selective laser melting (SLM), preformed and CAD-CAM implant abutments. Methods: Thirty internal connection, endosseous dental implants (Ø 4.0 mm x 10 mm, Dentium) were mounted in Polymethyl methacrylate vertically. Ten preformed Titanium alloy (Ti) abutments with 1 mm soft tissue height and Ø 4.5 mm were included as controls. Ten each of Y-TZP and SLM-CoCr, abutment/crowns were fabricated using CAD-CAM milling (CAD-CAM-ZrO) and SLM techniques. Surface micro-roughness (Ra) of the fabricated implant abutment/crown was evaluated with a 3D optical non-contact microscope. All implant restorations were torqued to implants (30 Ncm) using a Tohnichi BTGE digital torque gauge and were analyzed with Bruker micro-CT (Skyscan 1173) to detect micro-gaps at pre-selected points at implant abutment interface. The Ra and misfit data were compared using ANOVA, Tukey-Kramer, Kruskal-Wallis test and Pearson correlation (p < 0.05). Results: Mean Ra among SLM CoCr abutments [0.88 (0.09) µm] were lower than CAD-CAM-ZrO and higher than preformed Ti abutments. Horizontal misfit among SLM-CoCr [45.43 (9.41) µm] and preformed Ti [36.87 (13.23) µm] abutments was not statistically different (p > 0.05). Misfit was significantly higher in Y-TZP samples compared to SLM-CoCr (p = 0.031) and preformed Ti abutments (p = 0.01). Preformed Ti abutments showed significantly lower misfit compared to SLM-CoCr abutments (p = 0.01). A positive linear correlation was observed between the surface roughness (Ra) and vertical misfit (r = 0.61, p < 0.05). Conclusion: SLM CoCr abutments showed rough surface compared to preformed Ti abutments, while horizontal misfit was comparable among SLM-CoCr and preformed abutments. Misfit was significantly greater in Y-TZP abutments, compared to SLM and preformed abutments. SLM abutment fabrication technique needs further improvement to provide better fit and surface topography. [ABSTRACT FROM AUTHOR]

Restorative material selection has become increasingly challenging due to the speed of new developments in the field of dental material science. The present narrative review gives an overview of the current indications for implant abutments and restoration materials for provisional and definitive implant‐supported fixed dental prostheses in partially edentulous patients. For single implant restorations, titanium base abutments for crowns are suggested as an alternative to the conventional stock‐ and customized abutments made out of metal or zirconia. They combine the mechanical stability of a metallic connection with the esthetic potential of ceramics. For multiple‐unit restorations, conical titanium bases especially designed for bridges are recommended, to compensate for deviating implant insertion axes and angulations. Even though titanium base abutments with different geometries and heights are available, certain clinical scenarios still benefit from customized titanium abutments. Indications for the definitive material in fixed implant restorations depend on the region of tooth replacement. In the posterior (not esthetically critical) zone, ceramics such as zirconia (3–5‐Ymol%) and lithium‐disilicate are recommended to be used in a monolithic fashion. In the anterior sector, ceramic restorations may be buccally micro‐veneered for an optimal esthetic appearance. Lithium‐disilicate is only recommended for single‐crowns, while zirconia (3–5‐Ymol%) is also recommended for multiple‐unit and cantilever restorations. Attention must be given to the specific mechanical properties of different types of zirconia, as some feature reduced mechanical strengths and are therefore not indicated for all regions and restoration span lengths. Metal‐ceramics remain an option, especially for cantilever restorations. [ABSTRACT FROM AUTHOR]

(1) Background: Recent digital workflows are being developed for full-arch rehabilitations supported by implants with immediate function. The purpose of this case series is to describe a new digital workflow for the All-on-4 concept. (2) Methods: The patients were rehabilitated using the All-on-4 concept with a digital workflow including computerized tomography scanning, intra-oral scanning, and CAD-CAM production of the temporary prosthesis, with the 3D printing of stackable guides (base guide, implant guide, and prosthetic guide). The passive fit of the prostheses and the time to perform the rehabilitations were evaluated. (3) Results: The digital workflow allowed for predictable bone reduction, the insertion of implants with immediate function, and the connection of an implant-supported prosthesis with immediate loading. The time registered to perform the full-arch rehabilitations (implant insertion, abutment connection, prosthesis connection) was below 2 hours and 30 min. No passive fit issues were noted. (4) Conclusions: within the limitation of this case series, the digital workflow applied to the All-on-4 concept using stackable base-, implant-, and prosthetic guides constitutes a potential alternative with decreased time for the procedure without prejudice of the outcome. [ABSTRACT FROM AUTHOR]

Background: In this study, we aimed to compare the effects of conventional and digital impressions on several parameters (inter-implant distance, intra-implant distance, inter-implant axis, and intra-implant axis) of three implants in curved lines and straight lines by using a laboratory scanner (LBS) versus an intra-oral scanner (IOS). Methods: Two 3D models were fabricated using a printer, each model with three internal hex implants analogues at the positions of 15#,16#,17# (straight line) and 12#,13#,14# (curved line). Standard intra-oral scan bodies (ISBs) were used, and the two models were scanned using 7 Series dental wings (LBS, reference model), followed by ten scans with Primescan (digital method). Standard Tessellation Language (STL) files were created. Five polyether impressions were taken from each model (straight and curved), and gypsum type 4 models were poured; each model was scanned five times to create a total of 25 STL files for each group (conventional method). The comparison between all the STL files (conventional and digital) was made by superimposition of the STL files on the STL reference model laboratory file using a 3D analyzing software. A Kolmogorov–Smirnov test was performed, followed by Mann–Whitney tests and Wilcoxon signed-rank tests. (p < 0.05). Results: For the conventional method, the mean errors were significantly higher for the curved line model (12–14) compared to the straight line model (15–17) for most parameters (p < 0.05). For the digital method, the mean errors were significantly higher for the curved-line model (12–14) compared to the straight line model (15–17) in half of the parameters (p < 0.05). Within the curved line model (12–14) and the straight line model (15–17), the mean errors between the conventional method and the digital method were not significant for most variables. Conclusions: The difference between curved lines and straight lines has an impact on the mean error of the conventional method. Both methods are reliable for straight and curved lines in partially dentate situations. [ABSTRACT FROM AUTHOR]

Background: The objective of this study was to evaluate the pain and inflammatory response in soft tissues using healing and prosthetic abutments of different diameters and lengths. Methods: The study population was rehabilitated with Astra Tech EV single implants (Dentsply Sirona, Atlantis, Dentsply Sirona S.A., Barcelona, Spain) of 4.2 and 4.8 millimetres in diameter in the upper and lower maxilla and loaded with custom abutments digitally designed using Dentsply Sirona's Virtual Atlantis Design software (Atlantis WebOrder, Dentsply Sirona S.A., Barcelona, Spain), version 4.6.5. The custom abutments had a larger diameter than the healing abutments to evaluate for biomarkers through ELISA. Results: Rehabilitations in the mandible and with healing abutments with diameters less than 4.29 mm and rehabilitators with diameters less than 2.18 mm elicited a higher pain and inflammatory response and, in turn, higher interleukin-1β values. Conclusions: Greater inflammation was evident in cases in which healing abutments with reduced diameter were used compared to the same subsequent rehabilitation with prosthetic abutments with larger diameters. [ABSTRACT FROM AUTHOR]

Abstract Purpose A high transfer accuracy of the intraoral implant position to a model is required, to manufacture implant-supported restorations. However, clinically relevant deviations persist between the intraoral implant position and the model obtained, even for the benchmark conventional custom implant impressions with polyether. Thus, new approaches using 3-D printed impression trays may increase the transfer accuracy of implant impressions. The ability to adjust parameters such as the thickness of the layers and the influence of the openings in the impression tray could potentially affect accuracy. Methods Four different types of impression trays (n = 10 for each group) for the conventional impression technique were investigated: conventional custom impression tray, customized foil tray, chairside 3-D printed impression tray with the SHERA system, and the Primeprint system using an implant master model with four implants in the posterior region and a reference cube. After plaster model casting, all models were measured using a coordinate measuring machine, and the deviation from the reference dataset was determined. A statistical ANOVA analysis was performed (p 0.05). Conclusions Chairside 3-D printed impression trays significantly increase the transfer accuracy for implant impression taking. Graphical Abstract

Objective: Immediate implants and immediate alveolar sealing have been a widely utilized treatment with high predictability and biological advantages. The improvement in technology has made it possible to simplify clinical processes. The aim of the present report was to describe the complete digital workflow of the Biologically oriented preparation technique for immediate posterior implant, immediate provisionalization and fabrication of definitive implant crowns. Clinical Considerations: The surgical process and prosthetic management to preserve the gingival contours of the extracted natural tooth during immediate implant placement and provisionalization are described. Additionally, during the same clinical intervention, the definitive intraoral digital implant scans for capturing the implant position, peri‐implant tissue contours, adjacent and antagonist dentition, and profile emergence of the interim implant crown are captured for the fabrication of the definitive crown. Conclusions: Based on the technique described, the immediate implant placement and provisionalization in the posterior area provides biological and clinical advantages, reducing the number of abutment‐implant disconnections and the number of clinical appointments, as well as increases patient comfort. Clinical Significance: The present article describes a technique for an immediate implant placement and provisionalization in the posterior region for maintaining the gingival architecture of the extracted tooth. During the same appointment, the implant position, peri‐implant tissue contours, and adjacent and antagonist dentition, and profile emergence of the interim implant crown are captured by using an intraoral scanner and used for the fabrication of the definitive crown. This technique aims to reduce the number of abutment‐implant disconnections and clinical appointments. [ABSTRACT FROM AUTHOR]

With the life expectancy increasing, there is a growing need for prosthetic dental treatments to restore the oral health, function, and quality of life of edentulous patients. Presently, only a few articles are available describing the oral rehabilitation of patients with severely resorbed ridges with milled complete dentures. This clinical case report provides a straightforward protocol consisting of a combination of analog and digital techniques for the rehabilitation of edentulous patients with severely resorbed ridges with milled fixed and removable complete dentures. This technique permits the minimization of the number of appointments, improves patient comfort, allows for the digital archiving of important clinical data, and permits the manufacture of prostheses with improved mechanical properties. These favorable outcomes were achieved by using the patient's existing PMMA complete denture as a custom tray for a final impression with light-bodied Polyvinylsiloxane. Subsequently, the resulting models were digitized, and a digital complete denture was designed and manufactured in an expedited manner using CAD-CAM techniques. Therefore, this case report highlights the potential of CAD/CAM technology to predictably restabilize oral functions and improve patients' quality of life. [ABSTRACT FROM AUTHOR]

Purpose: Hybrid abutment crowns (HACs) made from monolithic ceramics represent an efficient option for single restorations on implants. However, long‐term data are scarce. The purpose of this clinical trial was to evaluate the survival and complication rates of CAD‐CAM fabricated HACs over a time period of at least 3.5 years. Materials and Methods: Twenty‐five patients with a total of 40 HACs made of monolithic lithium disilicate ceramic bonded to a titanium base CAD‐CAM abutment were retrospectively evaluated. All implants and screw‐retained restorations were placed and manufactured in the same department of a university hospital. Only crowns that had been in service for more than 3.5 years were included in the study. HACs were evaluated regarding technical and biological complications. Functional Implant Prosthodontic Scores (FIPS) were obtained. Results: The mean observation time was 5.9 ± 1.4 years. Implant survival was 100%, and HAC survival was 97.5%. Over the observation period, one crown fracture was observed, necessitating refabricating of the restoration. Three minor biological complications were found. The overall mean FIPS score was 8.69 ± 1.12 points. Conclusions: Within the limitations of this study, monolithic screw‐retained HACs milled from lithium disilicate ceramics and bonded to titanium bases appeared to be a reliable treatment option over more than 3.5 years due to their low biological and technical complication rates. [ABSTRACT FROM AUTHOR]

Introduction:The accumulated experience until now, has demonstrated that, when applying a prosthetic restoration on teeth or on an implant support, complications of a technical nature occur much more frequently than those of a biological nature. Phenomena such as the corrosion of the metal supporting structure (framework) or the exfoliation of the veneering ceramics or even the invoice on these structures, with the unaesthetic visualization of the metal, are the most frequent. Purpose: Highlighting the disadvantages of restorations on CR-CO metal support compared to those made of monolithic zirconia. The advantages of modern technology that add considerable improvement in aesthetics over time, especially in the cervical area, can be considerably diminished with the help of CAD/CAM (Computer Aided Design/ Computer Aided Manufacturing) technology. If the traditional prosthetics does notmore left to say, CAD/CAM technology is currently influencing the entire field of activity in clinical dentistry and dental technology. Material and method: In this article, we present a study carried out during 5 years in which we performed both metal-ceramic rehabilitation works using the classic method and monolithic zirconia using CAD-CAM technology on a number of 15 patients. Oral rehabilitation was carried out in the frontal area, analyzing the complications arising for the two prosthetic options during the 5 years. Results: The technology complements, or even completely replaces, the conventional processes of confectioning prosthetic restorations. Moreover, the modern CAD/CAM systems allow the creation of high-quality prosthetic parts that can be individually adapted to the clinical situation and the financial possibilities of the patients. During the 5 years, complications appeared in the metal-ceramic restorations, primarily represented by unaesthetic gingival retraction and the highlighting of the supporting metal. The realization of very precise prosthetic restorations respecting the technical characteristics of the materials depends on the technological flow, on the coordination of the technological stages in the process of making them, so that the CAD/CAM technology becomes superior to the conventional manufacturing stages. Conclusions: It is known the fact that each manual stage is connected to an error potential more or less important. The elimination of these stages prone to errors, such as the casting of the prosthetic works, will be a great step in the elevation of the precision degree of the prosthetic pieces. Merely the ones said untill now justify the use of the CAD/CAM technologies in the daily activity in the dental technique laboratories. [ABSTRACT FROM AUTHOR]

Background: The purpose of this in vitro study was to compare the inter-implant distance, inter-implant axis, and intra-implant axis of three implants in a straight line by using a laboratory scanner (LBS) versus an intra-oral scanner (IOS) with two different intra-oral scan bodies (ISBs). Methods: A 3D model was printed with internal hex implant analogs of three implants in positions 15#, 16#, and 17#. Two standard intra-oral scan bodies (ISBs) were used: MIS ISB (two-piece titanium) and Zirkonzhan ISB (two-piece titanium). Both ISBs were scanned using 7 Series dental wings (LBS) and 30 times using Primescan (IOS). For each scan, a stereolithography (STL) file was created and a comparison between all the scans was performed through superimposition of the STL files by using 3D analysis software (PolyWorks® 2020; InnovMetric, Québec, QC, Canada). A Kolmogorov–Smirnov test was performed followed by a Mann–Whitney test (p < 0.05). Results: The change in inter-implant distance for the MIS ISB was significantly lower compared to the ZZ (p < 0.05). The change in intra-implant angle was significantly lower for the ZZ ISB compared to MIS (p < 0.05). The changes in inter-implant angle between the mesial and middle and between the middle and distal were significantly lower for MIS compared to ZZ in contrast to mesial to distal, which was significantly higher (p < 0.05). Conclusions: Both ISBs showed differences in all the parameters between the LBS and the IOS. The geometry of the scan abutment had an impact on the inter-implant distance as the changes in the inter-implant distance were significantly lower for the MIS ISB. The changes in the intra-implant angle were significantly lower for the ZZ ISB. There is a need for further research examining the influence of geometry, material, and scan abutment parts on the trueness. [ABSTRACT FROM AUTHOR]

Objective: To describe the clinical use of nitride‐coated titanium CAD/CAM implant abutments in the maxillary esthetic zone in two patients with high esthetic and functional demands and, to highlight the advantages of nitride‐coated milled titanium abutments when compared to stock/custom titanium, one‐piece monolithic zirconia, and hybrid metal‐zirconia implant abutments. Clinical Considerations: Due to the inherent mechanical and esthetic clinical challenges, single implant‐supported reconstructions in the maxillary esthetic zone are a complex restorative treatment. While CAD/CAM technology has been suggested to enhance and ease implant abutment design and manufacturing, implant abutment material selection remains as a critical decision affecting restoration's long‐term clinical outcomes. To date, considering the esthetic disadvantages of conventional titanium implant abutments, the mechanical limitations of one‐piece zirconia abutments and the manufacturing time and costs associated with hybrid metal‐zirconia abutments, no abutment material can be considered "ideal" for all clinical scenarios. Due to their biocompatibility, biomechanical characteristics (hardness and wear resistance), optical properties (yellow color), and peri‐implant soft tissue esthetic integration, the use of CAD/CAM titanium nitride‐coated implant abutments has been suggested as a predictable implant abutment material in mechanically challenging but esthetically demanding clinical situations, as the maxillary esthetic zone. Conclusions: Two patients requiring a combined tooth‐implant restorative treatment in the maxillary esthetic zone were treated using CAD/CAM nitride coated titanium implant abutments. The principal advantages of TiN coated abutments include comparable clinical outcomes to stock abutments, optimal biocompatibility, adequate fracture, wear, and corrosion resistance, reduced bacterial adhesion, and excellent esthetic integration with adjacent soft tissues. Clinical Significance: Clinical reports and short term mechanical, biological and esthetic clinical outcomes indicate that CAD/CAM nitride coated titanium implant abutments can represent a predictable restorative alternative to stock/custom and metal/zirconia implant abutments and be considered a clinical relevant option in mechanically challenging but esthetically demanding situations, as often found in the maxillary esthetic zone. [ABSTRACT FROM AUTHOR]

This study evaluated the reliability of the chair-side CAD-CAM surgical guide (CSG) in the anterior maxilla by comparing its accuracy with the laboratory 3D-printed surgical guide (3DSG) and manual surgical guide (MSG) concerning different levels of dentists' surgical experience. MATERIALS AND METHODS. Ten surgical guides of each type (MSG, 3DSG, and CSG) were fabricated on a control study model with missing right and left central incisors. Sixty implants were placed in 30 study models by two dentists (one inexperienced and one experienced) using three different types of surgical guides. Horizontal deviations at shoulder and at apex, vertical, and angular deviations were measured after superimposing the planned and placed implant positions in the software. Kruskal-Wallis and Mann-Whitney U tests were used to compare the accuracy of three types of surgical guides in each dentist group and the accuracy of each surgical guide between two dentists (α = .05). RESULTS. There were no significant differences in any deviations between CSG and 3DSG, apart from angular deviation, for both dentists' groups. Moreover, both CSG and 3DSG showed no significant differences in accuracy between the two dentists (P > .05). In contrast, MSG demonstrated significant differences from CSG and 3DSG and a significant difference in accuracy between the two dentists (P < .05). CONCLUSION. CSG provides superior accuracy to MSG in implant placement in the maxillary anterior region and is comparable to 3DSG at different levels of surgical experience, while offering the benefits of shorter manufacturing time and reduced patient visits. [ABSTRACT FROM AUTHOR]

Obtaining accurate models and well-fitting prostheses during the fabrication of complete implant-supported prostheses has been a significant challenge. Conventional impression methods involve multiple clinical and laboratory steps that can lead to distortions, potentially resulting in inaccurate prostheses. In contrast, digital impressions may eliminate some of these steps, leading to better-fitting prostheses. Therefore, it is important to compare conventional and digital impressions for producing implant-supported prostheses. This study aimed to compare the quality of digital intraoral and conventional impressions by measuring the vertical misfit of implant-supported complete bars obtained using both types of techniques. Five digital impressions using an intraoral scanner and five impressions using elastomer were made in a four-implant master model. The plaster models produced with conventional impressions were scanned in a laboratory scanner to obtain virtual models. Screw-retained bars (n = five) were designed on the models and milled in zirconia. The bars fabricated using digital (DI) and conventional (CI) impressions were screwed to the master model, initially with one screw (DI1 and CI1) and later with four screws (DI4 and CI4), and were analyzed under a SEM to measure the misfit. ANOVA was used to compare the results (p < 0.05). There were no statistically significant differences in the misfit between the bars fabricated using digital and conventional impressions when screwed with one (DI1 = 94.45 µm vs. CI1 = 101.90 µm: F = 0.096; p = 0.761) or four screws (DI4 = 59.43 µm vs. CI4 = 75.62 µm: F = 2.655; p = 0.139). Further, there were no differences when the bars were compared within the same group screwed with one or four screws (DI1 = 94.45 µm vs. DI4 = 59.43 µm: F = 2.926; p = 0.123; CI1 = 101.90 µm vs. CI4 = 75.62 µm: F = 0.013; p = 0.907). It was concluded that both impression techniques produced bars with a satisfactory fit, regardless of whether they were screwed with one or four screws. [ABSTRACT FROM AUTHOR]