6 results on '"Bensefa‐Colas, L."'
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2. Taking assessment and documentation of clinical relevance one step further – a suggestion to improve individual documentation and epidemiological usability
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Uter, W., Bauer, A., Bensefa-Colas, L., Brans, R., Crépy, M.-N., Giménez-Arnau, A., Filon, F.L., Hadzavdic, S.L., Pesonen, M., Schuttelaar, M.-L.A., Lidén, C., Wilkinson, M., and Public Health Research (PHR)
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conference abstract ,diagnosis ,software ,adult ,occupational eczema ,practice guideline ,pilot study ,occupational contact dermatitis ,selection of allergen ,individual documentation ,feasibility study ,allergy ,documentation ,major clinical study ,medical history ,dermatology ,Europe ,female ,publication ,male ,hapten ,occupation ,controlled study ,human ,patch test ,allergen - Abstract
BACKGROUND: Full assessment of patients with (occupational) contact dermatitis should ideally include a standardized investigation of irritant exposures in addition to information pertaining to possible allergy guiding the selection of allergens (haptens) to be tested. Positive results of skin tests, performed according to current guidelines, are evaluated in terms of their clinical relevance. However, such diagnostic information is hitherto ill-represented in clinical documentation systems (patch test software) serving departmental documentation needs, and also in surveillance registries based upon these. OBJECTIVES: To develop, implement as a pilot study, and analyse concerning feasibility and contents a new concept of representing a full scope of diagnostic information utilized when diagnosing patients with (occupational) contact dermatitis. METHODS: Based on a European working group discussion on items to document and catalogue lists to use for this purpose, an online documentation system to collect data was set up, followed by a pilot use involving 9 dermatology departments across Europe. RESULTS: Data on 176 patients with suspected occupational hand dermatitis were included. Data were analysed with regard to occupations, product categories, substances (haptens), source of information the evaluation was based upon, and various combinations of these factors, to illustrate the usefulness of the proposed data representation. CONCLUSIONS: An improved method of data collection is presented which more accurately links allergen to exposure and to clinical disease and patient history, and thus better represents clinical relevance. This enables more precise analysis of causation of contact dermatitis, occupational or non-occupational, and thereby better targeting of prevention on an individual basis. In addition to the benefits for individual documentation, the surveillance of contact dermatitis is expected to be enhanced by the suggested concept, allowing a more in-depth investigation of profiles of patients at risk for certain allergies, while still serving other well-proven purposes, eg time trend analyses.
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- 2018
3. Occupational contact urticaria: lessons from the French National Network for Occupational Disease Vigilance and Prevention (RNV3P)
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Bensefa-Colas, L., Telle-Lamberton, M., Faye, S., Bourrain, J.-L., Crépy, M.-N., Lasfargues, Gérard, Choudat, D., Le Barbier, M., Marny, C., Doutrellot-Philippon, C., Gislard, Antoine, Gehanno, Jean-François, Rollin, Laetitia, Roquelaure, Yves, Petit, Audrey, Verdun-Esquer, Catherine, Leclerc, I., Dewitte, J.D., Loddé, B., Clin, B., Momas, I., Barbier, M. Le, Marquignon, M.F., Chamoux, A., Dutheil, F., Andujar, P., Pairon, J.C., Smolik, H.J., Fernandez, N., Bonneterre, V., Michel, E., Gehanno, J.F., Frimat, P., Nisse, C., Druet-Cabanac, M., Massardier, A., CHARBOTEL, B., Lehucher-Michel, M.P., Roulet, A., Lesage, F.X., Paris, C., Penven, E., Dupas, D., Descatha, A., Mediouni, Z., Léger, D., Bayon, V., Langrand, J., Villa, A., Ben-Brik, E., Martinez, H., Deschamps, F., Gouyet, T., Verger, C., FONTANA, L., Pélissier, C., Gonzalez, M., Nourry, N., Esquirol, Y., Hérin, F., Haguenoer, K., Hôpital Cochin [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Observatoire régional de santé Île-de-France [Paris, France] (ORSIDF), Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail (ANSES), Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Epidémiologie Environnementale : Impact Sanitaire des Pollutions (EA 4064), Université Paris Descartes - Paris 5 (UPD5), Service de santé au travail et pathologie professionnelle [Rouen], CHU Rouen, Normandie Université (NU)-Normandie Université (NU)-Université de Rouen Normandie (UNIROUEN), Normandie Université (NU), Aliments Bioprocédés Toxicologie Environnements (ABTE), Université de Caen Normandie (UNICAEN), Laboratoire d'Informatique, de Traitement de l'Information et des Systèmes (LITIS), Institut national des sciences appliquées Rouen Normandie (INSA Rouen Normandie), Institut National des Sciences Appliquées (INSA)-Normandie Université (NU)-Institut National des Sciences Appliquées (INSA)-Normandie Université (NU)-Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Université Le Havre Normandie (ULH), Centre Hospitalier Universitaire d'Angers (CHU Angers), PRES Université Nantes Angers Le Mans (UNAM), Épidémiologie en Santé au Travail et Ergonomie (IRSET-ESTER), Institut de recherche en santé, environnement et travail (Irset), Université d'Angers (UA)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-École des Hautes Études en Santé Publique [EHESP] (EHESP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique )-Université d'Angers (UA)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-École des Hautes Études en Santé Publique [EHESP] (EHESP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), CHU Bordeaux [Bordeaux], Faculté des Sciences Pharmaceutiques et Biologiques / Laboratoire d'Hygiène et de Santé Publique, Université Le Havre Normandie (ULH), Normandie Université (NU)-Institut national des sciences appliquées Rouen Normandie (INSA Rouen Normandie), Institut National des Sciences Appliquées (INSA)-Normandie Université (NU)-Institut National des Sciences Appliquées (INSA), Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique )-Institut National de la Santé et de la Recherche Médicale (INSERM)-École des Hautes Études en Santé Publique [EHESP] (EHESP)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Université d'Angers (UA)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique )-Institut National de la Santé et de la Recherche Médicale (INSERM)-École des Hautes Études en Santé Publique [EHESP] (EHESP)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Université d'Angers (UA), Centre Hospitalier Régional Universitaire de Brest (CHRU Brest), Service Pathologies Professionnelles, Centre Hospitalier Régional Universitaire de Brest (CHRU Brest)-Hôpital Morvan [Brest], Service de Santé au Travail et Pathologie Professionnellel [CHU Caen], Normandie Université (NU)-Normandie Université (NU)-CHU Caen, Normandie Université (NU)-Tumorothèque de Caen Basse-Normandie (TCBN)-Tumorothèque de Caen Basse-Normandie (TCBN), Univ Angers, Okina, Université Paris-Est (UPE), and RNV3P members: M Le Barbier, C Marny, C Doutrellot-Philippon, Y Roquelaure, A Petit, C Verdun-Esquer, I Leclerc, J D Dewitte, B Loddé, B Clin, M F Marquignon, A Chamoux, F Dutheil, P Andujar, J C Pairon, H J Smolik, N Fernandez, V Bonneterre, E Michel, J F Gehanno, P Frimat, C Nisse, M Druet-Cabanac, A Massardier, B Charbotel, M P Lehucher-Michel, A Roulet, F X Lesage, C Paris, E Penven, D Dupas, L Bensefa-Colas, D Choudat, A Descatha, Z Mediouni, D Léger, V Bayon, J Langrand, A Villa, E Ben-Brik, H Martinez, F Deschamps, T Gouyet, C Verger, A Gislard, L Rollin, L Fontana, C Pélissier, M Gonzalez, N Nourry, Y Esquirol, F Hérin, K Haguenoer
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Adult ,Male ,medicine.medical_specialty ,Adolescent ,Urticaria ,media_common.quotation_subject ,Occupational disease ,Dermatology ,Logistic regression ,Continuous variable ,Young Adult ,030207 dermatology & venereal diseases ,03 medical and health sciences ,Age Distribution ,0302 clinical medicine ,Environmental health ,medicine ,Humans ,Occupational contact dermatitis ,030212 general & internal medicine ,Occupations ,Sex Distribution ,Aged ,media_common ,Occupational contact urticaria ,[SDV.MHEP] Life Sciences [q-bio]/Human health and pathology ,business.industry ,Odds ratio ,Middle Aged ,medicine.disease ,3. Good health ,Surgery ,Dermatitis, Occupational ,Natural rubber latex ,Female ,France ,business ,[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology ,Vigilance (psychology) - Abstract
Summary Background Occupational contact urticaria (OCU) is an occupational contact dermatitis that can cause serious health consequences and disability at work. Objectives To describe OCU and its temporal trends by the main causal agents and activity sectors in a nationwide scheme in France. Methods Using data from the French National Network for Occupational Disease Vigilance and Prevention (RNV3P), we described OCU reported during the period 2001–10 and analysed the temporal trends of OCU and OCU attributed to the most frequent agents over the study period. Trends analyses were supported by reporting odds ratios using a logistic regression model with reference to 2001, or with time as a continuous variable. Results During the study period, 251 cases of OCU were reported in RNV3P, half of which were due to natural rubber latex, in particular in the health and social work activity sector (HSW). The number of these cases declined significantly over the study period (19% per year), and particularly after 2006. Conversely, the other causes of OCU did not decrease. Conclusions Using surveillance data from a French national network, this study has found that there was a significant decline in OCU due to natural rubber latex, particularly in the HSW, when powdered latex gloves were banned from French hospitals. Our results show the effectiveness of this preventive measure, and suggest that this practice should be extended to other sectors.
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- 2015
4. Effectiveness of the European chromium( vi ) directive for cement implementation on occupational allergic contact dermatitis occurrence: assessment in France and the U.K
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Bensefa-Colas, L., Stocks, S., McNamee, R., Faye, S., Pontin, F., Agius, M., Lasfargues, G., Bonneterre, Vincent, Telle-Lamberton, M., Momas, I., members, RNV3P, Centre de Diagnostic et de Thérapeutique, Hôpital de l’Hôtel-Dieu [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (APHP), Epidémiologie Environnementale : Impact Sanitaire des Pollutions (EA 4064), Université Paris Descartes - Paris 5 (UPD5), University of Manchester [Manchester], Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail (ANSES), Environnement et Prédiction de la Santé des Populations (TIMC-IMAG-EPSP), Techniques de l'Ingénierie Médicale et de la Complexité - Informatique, Mathématiques et Applications, Grenoble - UMR 5525 (TIMC-IMAG), Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP)-IMAG-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP)-IMAG-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA), Centre Hospitalier Universitaire [Grenoble] (CHU), Observatoire régional de santé Ile-de-France HIV/sida (ORS), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), and Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019])-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019])
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inorganic chemicals ,Cement ,Ferrous sulphate ,Prevention effectiveness ,Letter ,Chromate conversion coating ,[SDV]Life Sciences [q-bio] ,technology, industry, and agriculture ,chemistry.chemical_element ,Dermatology ,Pulp and paper industry ,030210 environmental & occupational health ,030207 dermatology & venereal diseases ,03 medical and health sciences ,chemistry.chemical_compound ,Chromium ,0302 clinical medicine ,chemistry ,Contact allergy ,[SCCO.PSYC]Cognitive science/Psychology ,otorhinolaryngologic diseases ,Occupational allergic contact dermatitis ,Environmental science ,Hexavalent chromium ,ComputingMilieux_MISCELLANEOUS - Abstract
Hexavalent chromium is the main sensitizer in wet cement and a common cause of occupational allergic contact dermatitis (OACD), especially among workers in the construction industry.(1,2) The European Chromium VI directive(3) transposed into national regulations in France and UK respectively on May and January 2005, prohibits selling or using of hydrated cement with more than 0.0002% of chromium. This was achieved through the addition of ferrous sulphate to the dry product, allowing to reduce chromium VI to chromium III which is less sensitizing. This article is protected by copyright. All rights reserved.
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- 2017
5. Occupational skin diseases
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J. M. Ramada Rodilla, Margarida Gonçalo, Andreas Bauer, F. Larese Filon, Aleksandra Dugonik, V. Kohánka, R. Jurakić Tončić, S.M. John, Marija Bubaš, Maria Pesonen, Kristiina Aalto-Korte, L. Constandt, Jose Hernán Alfonso, Dagmar Simon, Beata Kręcisz, Vera Mahler, Razvigor Darlenski, Marie L A Schuttelaar, A. Giménez-Arnau, Patrick Koch, J. Pace, P.W. Mihatsch, C. Schuster, Jeanne D. Johansen, Branka Marinović, T.E. Danielsen, Petar Bulat, Mihaly Matura, HP Rast, Radoslaw Spiewak, Skaidra Valiukevičienė, Mark Wilkinson, Anders Boman, Marta Kieć-Swierczyńska, Suzana Ljubojević, J. Bourke, J. Chaloupka, Wolfgang Uter, L. Bensefa‐Colas, D. Mijakoski, S. Urbanček, Jelena Macan, J. Minov, Vesna Reljić, J.G. Bakker, P. Weinert, K. Ettler, Carmen Salavastru, Mahler, V., Aalto Korte, K., Alfonso, J. H., Bakker, J. G., Bauer, A., Bensefa Colas, L., Boman, A., Bourke, J., Bubaå¡, M., Bulat, P., Chaloupka, J., Constandt, L., Danielsen, T. E., Darlenski, R., Dugonik, A., Ettler, K., Gimenez Arnau, A., Gonã§alo, M., Johansen, J. D., John, S. M., Kiec Swierczynska, M., Koch, P., Kohã¡nka, V., Krecisz, B., LARESE FILON, Francesca, Ljubojeviä , S., Macan, J., Marinoviä , B., Matura, M., Mihatsch, P. W., Mijakoski, D., Minov, J., Pace, J., Pesonen, M., Ramada Rodilla, J. M., Rast, H., Reljic, V., Salavastru, C., Schuster, C., Schuttelaar, M. L., Simon, D., Spiewak, R., Jurakic TonÄ iÄ , R., Urbanä ek, S., Valiukeviä ienä , S., Weinert, P., Wilkinson, M., Uter, W., Coronel Institute of Occupational Health, Dermatology, AII - Inflammatory diseases, and Public Health Research (PHR)
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medicine.medical_specialty ,Pediatrics ,Standardization ,media_common.quotation_subject ,medicine.medical_treatment ,SOCIETY ,Dermatology ,contact dermatitis ,ILLNESS ,GUIDELINES ,DIAGNOSIS ,Skin Diseases ,Occupational medicine ,030207 dermatology & venereal diseases ,03 medical and health sciences ,0302 clinical medicine ,State (polity) ,Statutory law ,Surveys and Questionnaires ,contact dermatiti ,Epidemiology ,SURVEILLANCE ,INJURY ,Humans ,Medicine ,Occupation ,epidemiology ,030212 general & internal medicine ,Occupational skin diseases ,ammatti-ihotaudit ,media_common ,Rehabilitation ,EXPERTISES ,business.industry ,CONTACT-DERMATITIS ,occupational skin diseases ,questionnaire-based survey ,28 European countries ,ta3142 ,CARE ,CHRONIC HAND ECZEMA ,3. Good health ,Patient management ,Europe ,Occupational Diseases ,Infectious Diseases ,occupational skin diseases, EU, legislation ,Family medicine ,business - Abstract
BACKGROUND Work-related skin diseases (WSD) are caused or worsened by a professional activity. Occupational skin diseases (OSD) need to fulfil additional legal criteria which differ from country to country. OSD range amongst the five most frequently notified occupational diseases (musculoskeletal diseases, neurologic diseases, lung diseases, diseases of the sensory organs, skin diseases) in Europe. OBJECTIVE To retrieve information and compare the current state of national frameworks and pathways to manage patients with occupational skin disease with regard to prevention, diagnosis, treatment and rehabilitation in different European countries. METHODS A questionnaire-based survey of the current situation regarding OSD patient management pathways was carried out with experts on occupational dermatology and/or occupational medicine from 28 European countries contributing to the European Cooperation in Science and Technology (COST) Action TD 1206 (StanDerm) (www.standerm.eu). RESULTS Besides a national health service or a statutory health insurance, most European member states implemented a second insurance scheme specifically geared at occupational diseases [insurance against occupational risks (synonyms: insurance against work accidents and occupational injuries; statutory social accident insurance)]. Legal standards for the assessment of occupationally triggered diseases with a genetic background differ between different countries, however, in most European member states recognition as OSD is possible. In one-third of the countries UV light-induced tumours can be recognized as OSD under specific conditions. CONCLUSION OSD definitions vary between European countries and are not directly comparable, which hampers comparisons between statistics collected in different countries. Awareness of this fact and further efforts for standardization are necessary.
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- 2017
6. Extended documentation for hand dermatitis patients: Pilot study on irritant exposures
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Maria Pesonen, Wolfgang Uter, Andrea Bauer, Richard Brans, Marie-Noëlle Crépy, Carola Lidén, Lynda Bensefa-Colas, Suzana Ljubojević Hadžavdić, Mark Wilkinson, Francesca Larese Filon, Marie L A Schuttelaar, Ana Giménez-Arnau, Public Health Research (PHR), Uter, W., Bauer, A., Bensefa-Colas, L., Brans, R., Crepy, M. -N., Gimenez-Arnau, A., Larese Filon, F., Ljubojevic Hadzavdic, S., Pesonen, M., Schuttelaar, M. L., Wilkinson, M., and Liden, C.
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Male ,Allergic Contact ,exposure assessment ,Dermatitis ,Pilot Projects ,contact dermatitis ,epidemiology ,hand dermatitis ,irritants ,occupational skin disease ,Adult ,Aged ,Dermatitis, Allergic Contact ,Dermatitis, Irritant ,Dermatitis, Occupational ,Europe ,Female ,Humans ,Irritants ,Middle Aged ,Occupational Exposure ,Patch Tests ,Young Adult ,Health Personnel ,Irritant ,030207 dermatology & venereal diseases ,0302 clinical medicine ,Documentation ,Health care ,Epidemiology ,Immunology and Allergy ,Medicine ,Young adult ,hand dermatitis, irritants ,Patch Test ,Occupational ,Cohort ,Human ,medicine.medical_specialty ,irritant ,Dermatology ,03 medical and health sciences ,contact dermatiti ,Pilot Project ,COHORT ,OCCUPATIONAL SKIN DISEASES ,Exposure assessment ,business.industry ,CARE ,medicine.disease ,030228 respiratory system ,Emergency medicine ,Etiology ,hand dermatiti ,business ,Contact dermatitis - Abstract
BackgroundIrritant exposure may be a contributory cause or the sole cause of (occupational) hand dermatitis. However, the documentation of irritant exposures in clinical practice is not standardized.ObjectivesTo examine the feasibility and usefulness of a form with different items addressing both occupational and non-occupational irritant exposures in a semiquantitative way.MethodsBetween May 2016 and May 2017, successive patients with work-related hand dermatitis, irrespective of aetiology, were examined in 9 specialized European departments. Department-specific investigation was supplemented with the above proforma. The results were recorded by use of an anonymized secured online documentation system in a pilot study.ResultsAltogether, 193 patients were included; 114 females and 79 males, with a mean age of 40years (range 18-68years). The most common occupational group comprised healthcare workers (n =35); occupational exposure of the hands to gloves, dusts and water without detergents of >2hours/day was seen in 54.5%, 24.4% and 24.3% of patients, respectively. Non-occupational exposures rarely exceeded 2hours/day.ConclusionsIt is hoped that the set of descriptors will offer a basis for (clinical) epidemiological studies assessing the role of irritant exposures in occupational hand dermatitis, and to support a high level of quality and consistency in daily patient care.
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- 2018
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