1. Early cellular reactions induced by dinitrochlorobenzene in sensitized human skin
- Author
-
James A. Ross, D.J. Gawkrodger, J.A.A. Hunter, Eva McVittie, P.A. Botham, M.M. Carr, and I.C. Stewart
- Subjects
Male ,Pathology ,medicine.medical_specialty ,Allergy ,Time Factors ,Langerhans cell ,Fluorescent Antibody Technique ,Human skin ,Dermatology ,Dermatitis, Contact ,Immunoenzyme Techniques ,Dermis ,Immunopathology ,Biopsy ,Dinitrochlorobenzene ,medicine ,Humans ,Nitrobenzenes ,Aged ,Skin ,medicine.diagnostic_test ,business.industry ,Antibodies, Monoclonal ,Skin test ,Middle Aged ,Patch Tests ,medicine.disease ,medicine.anatomical_structure ,Langerhans Cells ,Female ,business ,Contact dermatitis - Abstract
SUMMARY Serial biopsies during the first 24 hours after dinitrochlorobenzene (DNCB) challenge in fifteen sensitized patients have shown that DNCB associates with Langerhans cells within 1 hour of application, and has reached the dermis around the appendages by 6 hours.
- Published
- 1984
- Full Text
- View/download PDF