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Introduction Brittle nails are fragile or split nails; they affect 20% of the population and may be primary or secondary to different conditions. The aim of our studies was to evaluate the efficacy and tolerability of a new water-based nail-strengthening treatment containing hyaluronic acid and Pistacia lentiscus with daily application for a period of 1–3 months for one study (n = 30) and up to 6 months for a second study (n = 30). Methods In total, we enrolled 60 patients of both sexes with brittle and weak nails due to primary or secondary causes and evaluated the efficacy of this new product using subjective and objective methods: clinical evaluation, assessment of photographs, onychoscopy evaluation, investigator and patient global assessment, dynamic optical coherence tomography (D-OCT) and reflectance confocal microscopy (RCM). Results Studies subjects presented a statistically significant improvement in global assessment scale (GAS) scores at 14 days (GAS = 1.7 ± 0.6), 1 month (GAS = 1.4 ± 0.7) and at 3 months (GAS = 1±0.7) versus the GAS score obtained before treatment (1.9 ± 0.5) (p

Tinea capitis is a dermatophytic fungal infection of the scalp, hair follicles and hair shafts that is particularly contagious among children. Peak age range is in patients aged 3-7 years; African American children are significantly more affected than other races. Fungi of species of both genera Trichophyton and Microsporum can cause the infection. Common sources of infections are asymptomatic carriers (especially cats and guinea pigs), infected patients, or surviving fomites on inanimate objects. Oral antifungal medication is normally required for the treatment of tinea capitis. Topical antimycotic therapy alone usually is ineffective and is recommended for the management of tinea capitis only as adjunctive therapeutic option. We report herein a case of tinea capitis in a 70-year-old woman successfully treated with Sertaconazole nitrate 2% cream, Ciclopirox 1% cream and Ketoconazole 2% shampoo.

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