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Sensitive skin is common but until now there has been no scale for measuring its severity. The Sensitive Scale is a new scale with a 14-item and a 10-item version that was tested in 11 countries in different languages on 2,966 participants. The aim of this study was to validate the pertinence of using the Sensitive Scale to measure the severity of sensitive skin. The internal consistency was high. Correlations with the dry skin type, higher age, female gender, fair phototypes and Dermatology Life Quality Index were found. Using the 10-item version appeared to be preferable because it was quicker and easier to complete, with the same internal consistency and the 4 items that were excluded were very rarely observed in patients. The mean initial scores were around 44/140 and 37/100. The use of a cream for sensitive skin showed the pertinence of the scale before and after treatment. [ABSTRACT FROM AUTHOR]

Retinaldehyde (RAL) was proven effective in treating photodamaged skin. Topical treatments with specific intermediate-size hyaluronate fragments (HAFi, 50-400 kDa) have been shown to stimulate keratinocytes proliferation and epidermal hyperplasia. The aim of this open, multicentric, international study was to assess the efficacy of the combination RAL-HAFi in the correction of skin photoaging. Either RAL 0.05%-HAFi 0.5% (Eluage cream; group 1) or RAL 0.05%-HAFi 1% (Eluage antiwrinkle concentrate; group 2) or both products (group 3) were applied daily to the 1462 subjects during 90 days. Overall photoaging severity was evaluated in the three groups by the dermatologists at D0, D30, and D90 based on the Larnier's scale. Wrinkles and/or furrows and clinical signs of aging were evaluated using a 4-point scale. The skin microrelief of the crow's feet, evaluated by optical profilometry, was performed in subjects from group 3. The 3-month application significantly improved overall photoaging through decrease of the Larnier's score in the three groups ( P < 0.001). At D90, significant improvement of wrinkles was shown in groups 2 and 3 [forehead wrinkles (−19% and −10%, respectively, P < 0.001), nasolabial folds (−20% and −16%, P < 0.001), crow's feet (−27% in the two groups, P < 0.001), and perioral wrinkles (−34% and −23%, P < 0.001)]. Clinical signs of photoaging on the entire face improved significantly in groups 1 and 3 [elasticity (−32% and −33%, respectively, P < 0.001), hyperpigmentation (−34% and −31%, P < 0.001), and ptosis (−18% and −22%; P < 0.001)]. Results were confirmed using an optical profilometry technique. Products were very well tolerated. This clinical study showed the efficacy and value of the RAL-HAFi combination in the management of aging skin in a large cohort of patients. [ABSTRACT FROM AUTHOR]