156 results on '"Molina-Leyva A"'
Search Results
2. What Proportion of the Spanish Dermatology Caseload Corresponds to Pediatric Dermatoses? Results From the DIADERM National Random Sampling Survey.
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Martin-Gorgojo A, Del Boz J, Descalzo-Gallego MÁ, Arias-Santiago S, Molina-Leyva A, Gilaberte Y, Fernández-Crehuet P, Husein-ElAhmed H, Viera-Ramírez A, Fernández-Peñas P, Taberner R, Buendía-Eisman A, and García-Doval I
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- Adolescent, Child, Humans, Cross-Sectional Studies, Spain epidemiology, Skin Diseases diagnosis, Skin Diseases epidemiology, Dermatology, Acne Vulgaris
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Background: Visits for skin conditions are very common in pediatric primary care, and many of the patients seen in outpatient dermatology clinics are children or adolescents. Little, however, has been published about the true prevalence of these visits or about their characteristics., Material and Methods: Observational cross-sectional study of diagnoses made in outpatient dermatology clinics during 2 data-collection periods in the anonymous DIADERM National Random Survey of dermatologists across Spain. All entries with an International Classification of Diseases, Tenth Revision code related to dermatology in the 2 periods (84 diagnoses) were collected for patients younger than 18 years and classified into 14 categories to facilitate analysis and comparison., Results: In total, the search found 20 097 diagnoses made in patients younger than 18 years (12% of all coded diagnoses in the DIADERM database). Viral infections, acne, and atopic dermatitis were the most common, accounting for 43.9% of all diagnoses. No significant differences were observed in the proportions of diagnoses in the respective caseloads of specialist vs. general dermatology clinics or public vs. private clinics. Seasonal differences in diagnoses (January vs. May) were also nonsignificant., Conclusions: Pediatric care accounts for a significant proportion of the dermatologist's caseload in Spain. Our findings are useful for identifying opportunities for improving communication and training in pediatric primary care and for designing training focused on the optimal treatment of acne and pigmented lesions (with instruction on basic dermoscopy use) in these settings., (Copyright © 2023 AEDV. Publicado por Elsevier España, S.L.U. All rights reserved.)
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- 2023
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3. Nonvenereal Infections in Spanish Dermatology Clinics: Results of the DIADERM Study.
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Pulido-Pérez A, Descalzo-Gallego MA, Arias-Santiago S, Molina-Leyva A, Gilaberte Y, Fernández-Crehuet P, Husein-ElAhmed H, Viera-Ramírez A, Fernández-Peñas P, Taberner R, Buendía-Eisman A, and García-Doval I
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- Adult, Humans, Cross-Sectional Studies, Dermatology, Keratosis, Actinic, Skin Diseases epidemiology, Skin Diseases diagnosis, Skin Neoplasms
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Background and Objective: The burden of nonvenereal infections in Spanish dermatology practice has not yet been evaluated. The aim of this study was to analyze the overall weight of these infections in outpatient dermatology caseloads., Material and Methods: Observational cross-sectional study of diagnoses made by a random selection of dermatologists from the Spanish Association of Dermatology and Venereology (AEDV) working in outpatient dermatology clinics. The data were obtained through the anonymous DIADERM survey. Diagnoses of infectious diseases were selected using codes from the International Classification of Diseases, Tenth Revision. After excluding sexually transmitted infections, the diagnoses were classified into 22 groups., Results: Spanish dermatologists diagnosed an estimated 16190 (95% CI, 9338-23042) nonvenereal infections on average per week, a figure that accounted for 9.33% of the dermatology caseload. The most common diagnostic groups were nonanogenital viral warts (7475 diagnoses, 46.17% of nonvenereal infections), dermatophytosis (3336, 20.61%), and other viral infections (1592, 9.84%), which included Molluscum contagiosum infections. Nonvenereal infections were more common than noninfectious dermatologic conditions in private clinics (P<.0020) and adults (P<.00001). Patients with these infections were also more likely to be discharged than those with other conditions in both public (P<.0004) and private (P<.0002) practices., Conclusions: Nonvenereal infections are frequent in dermatology. They are the third most common reason for outpatient visits, behind actinic keratosis and nonmelanoma skin cancer. By enhancing the participation of dermatologists in the management of skin infections and encouraging interactions with other specialists, we will be able to carve out a niche in an area we have scarcely ventured into to date., (Copyright © 2023 AEDV. Publicado por Elsevier España, S.L.U. All rights reserved.)
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- 2023
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4. Dermatology Care in Spanish Public Hospitals: A Mapping Study of Health Care Resources and Medical and Surgical Activity in Dermatology Departments in 2019.
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Cuenca-Barrales C, Molina-Leyva A, Moreno-Ramírez D, de la Cueva P, Gilaberte Y, and Arias-Santiago S
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- Cross-Sectional Studies, Delivery of Health Care, Hospitals, Public, Humans, Pandemics, COVID-19 epidemiology, Dermatology
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Background and Objective: No recent data on health care resources and medical and surgical activity in Spanish dermatology departments are available in the literature. The aim of this study was to compile this information for 2019., Material and Methods: Cross-sectional study based on an online survey sent to the heads of dermatology departments at public hospitals in Spain., Results: Of the 162 department heads contacted, 59 answered the survey (participation rate, 36.4%). General findings included a shortage of staff, especially dermatologists, in hospitals of low and medium complexity. The main reason given for the shortage of dermatologists was a lack of interested applicants. Large hospital complexes had more infrastructure and equipment. Over 50% of the departments surveyed used a combination of in-person and virtual visits. Psoriasis units were the most common specialized care units. Approximately 75% of the hospitals had operating rooms with an anesthetist. More complex procedures such as sentinel lymph node biopsy and Mohs micrographic surgery were performed more often in large hospital complexes. Hospitalization and the presence of dermatology residents working call shifts were also more common in these hospitals. Teaching and research activity differed according to hospital complexity., Conclusions: We have mapped health care resource availability and medical and surgical activity in Spanish dermatology departments prior to the COVID-19 pandemic. Our findings could be useful for improving clinical management and defining future actions and areas for improvement., (Copyright © 2021 AEDV. Publicado por Elsevier España, S.L.U. All rights reserved.)
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- 2022
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5. Specialized Dermatology Training in Spain: Opinions of 53 Third-Year Dermatology Residents Surveyed in 2019.
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Montero-Vilchez T, Molina-Leyva A, Martinez-Lopez A, Buendia-Eisman A, Ortega-Olmo R, Serrano-Ortega S, and Arias-Santiago S
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- Spain, Surveys and Questionnaires, Dermatology education, Internship and Residency
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- 2021
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6. Proportion of Potentially Avoidable Referrals From Primary Care to Dermatologists for Cystic Lesions or Benign Neoplasms in Spain: Analysis of Data From the DIADERM Study.
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González-Cruz C, Descalzo MÁ, Arias-Santiago S, Molina-Leyva A, Gilaberte Y, Fernández-Crehuet P, Husein-ElAhmed H, Viera-Ramírez A, Fernández-Peñas P, Taberner R, Buendía-Eisman A, García-Doval I, and García-Patos V
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- Cysts diagnosis, Health Services Misuse prevention & control, Humans, Keratosis, Seborrheic diagnosis, Spain, Dermatology statistics & numerical data, Health Services Misuse statistics & numerical data, Primary Health Care statistics & numerical data, Referral and Consultation statistics & numerical data, Skin Diseases diagnosis
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Background and Objective: Skin lesions are a common reason for consulting a primary care physician. Current legislation in Spain states that purely aesthetic skin problems that do not pose a health problem are not to be treated within the National Health Service. The aim of this study was to estimate the proportion of referrals from primary care physicians to dermatologists that were for cystic lesions or benign tumors and could potentially have been avoided., Material and Methods: We consulted cases registered in the DIADERM study dataset, which is representative of dermatology practice in Spain, and collected the main diagnoses given on referring patients from primary care. A referral diagnosis was classified as potentially avoidable if it corresponded to one of the primary care discharge diagnoses listed in a consensus paper of the Andalusian section of the Spanish Academy of Dermatology and Venereology (AEDV)., Results: We collected 2171 main reasons for first-visit referrals to dermatologists; 686 of them (31.6%) were for cystic lesions or benign tumors and classified as potentially avoidable. In 478 cases (22%) the patients were discharged on the first visit. The most frequent diagnoses in such cases were seborrheic keratosis (9.3%) and melanocytic nevus (8.6%)., Conclusions: Nearly a third of referrals from primary care to a dermatologist were for cystic lesions and benign tumors and could have been avoided. A clearer understanding of our caseload can be useful for improving planning, training, and health care system management., (Copyright © 2019 AEDV. Publicado por Elsevier España, S.L.U. All rights reserved.)
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- 2019
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7. Clinical research in Dermatology: resources and activities associated with a higher scientific productivity.
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Molina-Leyva A, Descalzo MA, and García-Doval I
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- Bibliometrics, Cross-Sectional Studies, Humans, Surveys and Questionnaires, Biomedical Research statistics & numerical data, Dermatology, Efficiency, Periodicals as Topic statistics & numerical data
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Background: Clinical research papers and their derived metrics can be useful to assess the scientific production of medical and research centers. Diverse factors are probably associated to differences in scientific production. But there are scarce studies analyzing them. Resources are limited and have to be distributed efficiently. The objective of this study was to explore what resources and activities are potentially associated with a higher scientific productivity., Methods: A bibliometric study was performed to obtain information about scientific productivity. Papers included had to meet criteria to be considered clinical research in dermatology, additionally had to be published between the years 2005-2014, had to be included in Pubmed or Embase and had to include a Spanish center of dermatology as the correspondence address. Information about research resources and activities of the year 2015 was gathered by means of an online survey sent to the authors identified in the bibliometric study., Results: The search strategy returned 8617 papers and only 1104 of them (12.81%) met the inclusion criteria. 63 out of 113 centers responded to the survey (55.75%). Factors associated with a higher scientific productivity were: the size of the resident program, the amount of time specifically dedicated to research, a lower clinical workload, and the number of clinical trials performed in the last year., Conclusions: We have demonstrated that some factors are associated with a higher scientific productivity. Residency program, more research staff, clinical workload redistribution and research motivation/initiatives are key strategies that could improve scientific productivity of a center.
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- 2019
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8. Referral of Patients to Dermatology and Teledermatology Consultations in Spain. DIADERM Study.
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González-López G, Descalzo-Gallego MÁ, Arias-Santiago S, Molina-Leyva A, Gilaberte Y, Fernández-Crehuet P, Husein-El Ahmed H, Viera-Ramírez A, Fernández-Peñas P, Taberner R, García-Doval I, and Buendía-Eisman A
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- Adult, Child, Cross-Sectional Studies, Humans, Spain, Dermatology methods, Dermatology statistics & numerical data, Referral and Consultation statistics & numerical data, Skin Diseases diagnosis, Skin Diseases therapy, Telemedicine statistics & numerical data
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Background and Objectives: Understanding the origin and referral routes of patients seen in teledermatology and in-person dermatology consultations in Spain is of interest from the perspective of health care management. The objective of this study was to describe the referral routes and the frequency and characteristics of teledermatology consultations in Spain., Material and Methods: We performed a descriptive cross-sectional study of data collected over 6 days from the DIADERM study sample, which included the outpatients diagnosed by 80 Spanish dermatologists, selected by means of stratified random sampling. We studied the source and destination of patients based on funding, type of consultation, and age of the patients. We reported the frequency of teledermatology consultations, their origin and destination, type of funding, age of the patients, and most common diagnoses, and compared them with the same characteristics for in-person consultations., Results: In private consultations, most patients were direct clients, whereas the most frequent source in public consultations was primary care and the dermatologist. Sixty-six percent of patients were referred to dermatology and 27% were discharged. No differences in these percentages were found between public and private consultations. The ratio of follow-up to initial visits was 0.8 for public consultations and 0.2 for private consultations. Teledermatology accounts for 1% of consultations. Eighty percent of these come from primary care and 17% are direct visits. Thirty-three percent of these visits are referred to primary care - a greater proportion than in in-person consultations. Galicia, Andalusia, and Catalonia are the regions with the highest percentage of consultations., Conclusions: The results suggest that dermatologists in Spain have a considerable ability to resolve cases. Teledermatology accounts for a small percentage of consultations and access to these consultations is direct in a large percentage of cases., (Copyright © 2018 AEDV. All rights reserved.)
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- 2019
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9. Influence of Article Type on the Impact Factor of Dermatology Journals.
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Rodríguez-Lago L, Molina-Leyva A, Pereiro-Ferreirós M, and García-Doval I
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- Dermatology, Journal Impact Factor, Periodicals as Topic, Publishing classification
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Background and Objective: For scientific journals, achieving a high impact factor (IF) has become a goal in its own right. Our aim was to describe the influence of article type on the IF of dermatology journals., Material and Methods: We used the Scopus database to calculate an IF for Actas Dermo-Sifiliográficas and the major dermatology journals, excluding articles without abstracts, letters to the editor, and conference proceedings. Included articles were classified into 4 categories: case reports, original articles, narrative reviews, and other. We also calculated the mean IF for each article type. We then compared our results with IFs published by the Institute for Scientific Information., Results: The proportion of each type of article differed between journals. Original articles carried the greatest weight in the major journals (BJD, 76.8%; Contact, 81.1%; JAAD, 63.4%; JAMA Dermatol, 63.7%.) but not in Actas Dermo-Sifiliográficas, where only 31.7% were original research articles. A higher IF was associated with the publication of reviews and original articles; a lower IF was associated with the publication of case reports and other article types., Conclusions: Publishing case reports, which have lower citation rates, leads to a lower IF. Publishing reviews and original articles will lead to a higher IF. Journals that seek a higher IF should probably publish more reviews and original articles and fewer case reports. Editorial boards should seek a balance between the interests of their clinician readers and the journal's need for a higher IF., (Copyright © 2018 AEDV. Publicado por Elsevier España, S.L.U. All rights reserved.)
- Published
- 2018
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10. Clinical Research in Dermatology and Venereology in Spanish Research Centers in 2005 Through 2014: Results of the MaIND Study.
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Molina-Leyva A, Descalzo MA, and García-Doval I
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- Databases, Bibliographic, Evidence-Based Medicine, Humans, MEDLINE, Melanoma, Periodicals as Topic statistics & numerical data, Spain, Bibliometrics, Dermatology, Research statistics & numerical data, Venereology
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Background and Objective: Bibliometric indicators provide a useful measure of the number of clinical research articles published in scientific journals and their quality. This study aimed to assess the amount and quality of research carried out in Spanish dermatology centers and to describe the research topics., Material and Method: Bibliometric study of clinical research articles that met the inclusion criteria and had a definitive publication date between 2005 and 2014 in MEDLINE or Embase in which the corresponding author's affiliation was a Spanish hospital dermatology department or other center., Results: Of 8,617 articles found, 1,104 (12.81%) met the inclusion criteria. The main reason for excluding articles was that they did not have an evidence level of 4 or better. The main vehicle for reporting was the journal Actas Dermosifiliográficas, which published 326 articles (29.53%). Melanoma, the disease the researchers studied most often, accounted for 134 articles (12.13%)., Limitations: A limitation to bear in mind when interpreting the results is that we relied on the corresponding author's affiliation to identify articles reflecting research from a Spanish dermatology center. Thus, studies in which dermatologists participated would not be recognized if they were directed by other specialists., Conclusion: Only a small portion of articles published from Spanish dermatology centers can be considered clinical research, mainly because many publications provide a low level of scientific evidence. Most publications are case reports., (Copyright © 2017 AEDV. Publicado por Elsevier España, S.L.U. All rights reserved.)
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- 2018
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11. A Map of Clinical Dermatology Research Centers in Spain: Results of the MaIND Study.
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Molina-Leyva A, Descalzo MA, and García-Doval I
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- Academies and Institutes statistics & numerical data, Dermatology organization & administration, Hospitals statistics & numerical data, Humans, Publishing statistics & numerical data, Spain, Bibliometrics, Dermatology statistics & numerical data, Maps as Topic, Research statistics & numerical data
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Background and Objective: Bibliometric indicators and analyses of clinical research articles can help to quantify the scientific production of hospitals and institutions and identify their main areas of research. The aim of this study was to draw up a bibliometric map of clinical research in dermatology by Spanish hospitals and institutions through an analysis of quantitative, qualitative, and topic-based variables., Material and Method: Bibliometric study of clinical research articles that met the inclusion criteria and had a definitive publication date between 2005 and 2014 in PubMed or Embase in which the corresponding author's affiliation was a Spanish dermatology department or institution., Results: Barcelona and Madrid were the provinces with the highest number of articles and citations. The centers with the most articles and citations were Hospital Clínic and Instituto Valenciano de Oncología. Those 2 hospitals also produced the highest number of articles on the most common research topic identified: melanoma. Because the articles were selected on the basis of the affiliation of the corresponding author to a Spanish dermatology center, this analysis does not include collaborative studies or clinical research studies led by nondermatology centers., Conclusions: We have created a bibliometric map of clinical dermatology research in Spain that shows the distribution of scientific production and the main areas of research by province and hospital/institution. This map could be useful for education and research purposes., (Copyright © 2017 AEDV. Publicado por Elsevier España, S.L.U. All rights reserved.)
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- 2017
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12. ¿Cuál es la visión de los estudiantes de medicina sobre la Dermatología? Un estudio transversal usando la herramienta Mentimeter
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T. Montero-Vilchez, A. Molina-Leyva, A. Buendía-Eisman, and S. Arias-Santiago
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Dermatology ,RL1-803 ,Internal medicine ,RC31-1245 - Published
- 2024
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13. Insights into the Window of Opportunity and Outcome Measures in Patients with Moderate to Severe Hidradenitis Suppurativa Treated with Secukinumab: A Real-World Study
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Sofía Haselgruber, Pablo Fernández-Crehuet-Serrano, María Dolores Fernández-Ballesteros, Alicia Padial-Gómez, Juan Carlos Hernández-Rodríguez, Juan Ortiz-Álvarez, Pedro Navarro-Guillamón, Cristina Membrive-Jiménez, Carlos Cuenca-Barrales, and Alejandro Molina-Leyva
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Hidradenitis suppurativa ,Secukinumab ,Window of opportunity ,Therapeutic burden ,Response predictors ,HiSCR ,Dermatology ,RL1-803 - Abstract
Abstract Introducion The concept of a window of opportunity in hidradenitis suppurativa (HS) management suggests that early initiation of biological therapy leads to better outcomes, though its timing remains uncertain. Methods We conducted a retrospective observational multicenter study, including consecutive patients with moderate to severe HS who initiated secukinumab treatment following prior failure with systemic antibiotics or adalimumab. Therapeutic burden was defined as the sum of previous systemic treatment cycles and previous major surgical interventions for HS. Patients were followed up for 24 weeks. Main outcomes were safety and effectiveness, assessed through the proportion of patients achieving HS Clinical Response (HiSCR) and a 55% reduction in International HS Severity Score System (IHS4-55). Additionally, potential predictors of response to secukinumab were studied. Analysis was performed on an intention-to-treat basis. Results A total of 67 patients (33 men, 34 women) were included, with a mean age of 41.55 (11.94) years and a mean baseline IHS4 of 17.88 (11.13). The mean therapeutic burden was 6.06 (3.49). At week 24, 10.45% (7/67) of patients experienced adverse events, with three leading to treatment discontinuation. At week 24, 41.79% (28/67) of patients achieved HiSCR, and 44.78% (30/67) of patients achieved IHS4-55. HiSCR could not be calculated in 12 patients with a baseline AN count
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- 2024
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14. [Translated article] How do Medical Students Actually See Dermatology? A Cross-Sectional Study Using the Mentimeter App
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T. Montero-Vilchez, A. Molina-Leyva, A. Buendía-Eisman, and S. Arias-Santiago
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Dermatology ,RL1-803 ,Internal medicine ,RC31-1245 - Published
- 2024
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15. Safety and Effectiveness of Percutaneous Ultrasound-Guided Galvanic Current in Tunnels of Patients with Hidradenitis Suppurativa: A Pilot Study
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Alberto Soto-Moreno, Carlos Cuenca-Barrales, Salvador Arias-Santiago, José Antonio García-Vidal, Francesc Medina-Mirapeix, and Alejandro Molina-Leyva
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Hidradenitis suppurativa ,Galvanic current ,Intralesional therapy ,Pilot study ,Dermatology ,RL1-803 - Abstract
Abstract Introduction The recurrent nature of hidradenitis suppurativa (HS), even under maintained systemic treatment, makes it necessary to have effective local treatments; however, the response to these therapies is variable (44–81%). The application of galvanic current (GC) has demonstrated its utility in humans in treating lesions structurally similar to those of HS. With this background, the main objective of this study was to evaluate the efficacy and safety of ultrasound-guided percutaneous GC in inflamed and/or draining tunnels of HS. Methods This was an open study (one-way repeated measures design over time). Patients were evaluated at 4 and 12 weeks after receiving GC. A combined clinical response at week 12 (absence of suppuration/inflammation on examination and clinical interview) was considered the principal variable of efficacy. Adverse effects potentially associated with GC were reported by telephone and at each visit. Results Twenty-six patients were included, with a male/female ratio of 5:8. The mean age was 35.84 (13.14) years. At 12 weeks after the administration of GC, a complete response was achieved in 77% (20/26) of the treated lesions. No serious adverse effects were observed, and the mean procedural pain assessed by the numeric rating scale was 0.03 (0.2). Conclusion GC has proven to be effective and well tolerated in inflamed and draining tunnels of patients with HS.
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- 2024
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16. Unmet clinical needs, burden of disease and treatment patterns in hidradenitis suppurativa: Real‐world experience from Spain
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Eva Vilarrasa, Alejandro Molina‐Leyva, Víctor Martín, Emily Coak, Isabel Truman, Hayley Wallinger, Craig Richardson, and Antonio Martorell
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biologics ,disease burden ,epidemiology ,hidradenitis suppurativa ,quality of life ,therapeutics ,Dermatology ,RL1-803 ,Diseases of the genitourinary system. Urology ,RC870-923 - Abstract
Abstract Background Hidradenitis suppurativa (HS) is a chronic, inflammatory, debilitating skin disease. HS is difficult‐to‐treat, and a multifaceted treatment approach is recommended to achieve adequate clinical response. A greater understanding of HS treatment could help identify unmet clinical needs. Objectives To evaluate disease characteristics and treatment patterns in a real‐world population of patients with HS in Spain. Methods This retrospective analysis utilised data collected from the Adelphi HS Disease Specific Programme between November 2020 and April 2021. Dermatologists completed patient record forms (PRFs) for consulting HS patients. Outcomes included disease severity, HS clinical signs, quality of life measures, medical treatments and previous surgeries. Results Overall, 53 dermatologists completed 332 PRFs, each representing one patient with HS. Based on physician‐judged disease severity at sampling, 73.8%, 22.9% and 3.3% of patients were classified as mild, moderate or severe, respectively. Overall, patients presented with 2.8±2.7 (mean±SD) HS symptoms, which increased with worsening disease severity. The most frequently reported symptoms were ‘inflammation/redness of HS lesions/abscess’ (45.9%), general pain/discomfort (39.9%) and pain on sitting (32.3%). Overall, patients reported a mean±SD Dermatology Life Quality Index score of 4.7±4.8, which increased with worsening disease severity (mild, 3.9±4.3; moderate, 8.7±5.1; moderate to severe, 9.0±5.1). When asked what effect HS had on everyday activities, a large proportion of patients reported that HS sometimes or greatly affected personal appearance/self‐confidence (66.0%), mood (60.2%), close personal relationships (60.4%), motivation (38.3%), leisure activities (43.0%) and feelings about the future (33.6%). At the time of HS diagnosis, the most frequently prescribed treatment regimens were topicals (70.7%), antibiotics (57.6%) and antiseptics (32.2%). At the time of sampling, the most common treatment regimens were biologics (43.8%), topicals (34.9%) and antibiotics (32.2%). The mean±SD number of surgical interventions was 0.6±0.8; incision and drainage (31.3%), local or limited excision (13.0%), and wide surgical excision of all hair‐bearing skin (9.9%) were the most common surgeries. Conclusions These real‐world data suggest a high disease burden in patients with HS in Spain. Patients received multiple treatments, and a notable proportion underwent surgery. More data are needed to define optimal HS management strategies.
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- 2024
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17. Calidad de vida profesional en dermatología: impacto de la pandemia y propuestas de mejora
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A. Soto-Moreno, C. Ureña-Paniego, T. Montero-Vílchez, M. Sánchez-Díaz, P. Díaz-Calvillo, J.A. Rodríguez-Pozo, A. Molina-Leyva, A. Martínez-López, A. Buendía-Eisman, and S. Arias-Santiago
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Quality of life ,Work satisfaction ,Dermatology ,COVID-19 ,RL1-803 ,Internal medicine ,RC31-1245 - Abstract
Resumen: Antecedentes y objetivo: La calidad de vida profesional se define como el bienestar derivado del equilibrio entre las exigencias del ámbito laboral y los recursos para afrontarlas, el deterioro de la calidad de vida profesional puede contribuir en el síndrome de burnout o del profesional quemado. El objetivo de este estudio consiste en evaluar mediante cuestionario validado la calidad de vida profesional de los dermatólogos españoles. Material y métodos: Se diseñó un estudio transversal que incluyó dermatólogos españoles que respondieran a un formulario autoadministrado enviado a través de aplicaciones de mensajería online. El formulario incluyó datos sociodemográficos, 3 preguntas de respuestas abiertas y el Cuestionario de Calidad de Vida Profesional (CVP-35). Resultados: Se incluyó a 106 participantes en este estudio, siendo un 58% (62/106) mujeres. La edad media fue de 41 años (intervalo de confianza [IC] del 95%: 43,3-38,8). Las puntuaciones para el dominio «carga de trabajo» de CVP-35 fueron superiores en las mujeres (p = 0,02) y en los jefes de servicio (p = 0,005). La presión asistencial fue el tema tratado con más frecuencia como factor limitante de la calidad de vida laboral, y el principal cambio identificado tras la pandemia de COVID-19. Conclusiones: En nuestro estudio las mujeres refirieron una mayor carga de trabajo. El incremento de carga asistencial y de trabajo a distancia fueron los principales cambios por la pandemia de COVID-19. La presión asistencial es una gran limitante de la calidad de vida profesional de nuestros compañeros, reducirla mejoraría la satisfacción diaria y la calidad asistencial. Abstract: Background and objective: Quality of professional life (QPL) is defined as a sense of well-being derived from a balance between the challenges of work and the resources available to deal with them. Impaired QPL can contribute to burnout. The aim of this study was to evaluate QPL in Spanish dermatologists using a validated questionnaire. Material and methods: We designed a cross-sectional study in which Spanish dermatologists were invited to complete an online questionnaire sent out by messaging applications. The dermatologists were asked to provide sociodemographic information, answer 3 open questions, and complete the 35-item Spanish QPL questionnaire (Spanish abbreviation, CVP-35). Results: We analyzed the information submitted by 106 dermatologists (62 women, 58%) with a mean age of 41 years (95% CI, 43.3-38.8 years). Women and department heads scored significantly higher in the workload domain of the questionnaire (P = .02 and P = .005, respectively). A heavy caseload was mentioned as the main factor contributing to impaired QPL and the main change in the wake of the COVID-19 pandemic. Conclusions: Female dermatologists reported heavier workloads. Heavy caseloads and more remote work were the main changes identified after the COVID-19 pandemic. Heavy caseloads have a significant impact on the QPL of dermatologists in Spain. Reducing caseloads would improve general job satisfaction and quality of care provision.
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- 2024
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18. Editorial: Education in dermatology
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Alejandro Molina-Leyva and Salvador Arias-Santiago
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education ,teaching ,dermatology ,teledermatology ,technology ,Medicine (General) ,R5-920 - Published
- 2024
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19. [Translated article] Quality of Professional Life Among Dermatologists: Impact of the COVID-19 Pandemic and Suggestions for Improvement
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A. Soto-Moreno, C. Ureña-Paniego, T. Montero-Vílchez, M. Sánchez-Díaz, P. Díaz-Calvillo, J.A. Rodríguez-Pozo, A. Molina-Leyva, A. Martínez-López, A. Buendía-Eisman, and S. Arias-Santiago
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Calidad de vida ,Satisfacción laboral ,Dermatología ,COVID-19 ,Dermatology ,RL1-803 ,Internal medicine ,RC31-1245 - Abstract
Background and objective: Quality of professional life (QPL) is defined as a sense of well-being derived from a balance between the challenges of work and the resources available to deal with them. Impaired QPL can contribute to burnout. The aim of this study was to evaluate QPL in Spanish dermatologists using a validated questionnaire. Material and methods: We designed a cross-sectional study in which Spanish dermatologists were invited to complete an online questionnaire sent out by messaging applications. The dermatologists were asked to provide sociodemographic information, answer 3 open questions, and complete the 35-item Spanish QPL questionnaire (Spanish abbreviation, CVP-35). Results: We analyzed the information submitted by 106 dermatologists (62 women, 58%) with a mean age of 41 years (95% CI, 43.3-38.8 years). Women and department heads scored significantly higher in the workload domain of the questionnaire (P = .02 and P = .005, respectively). A heavy caseload was mentioned as the main factor contributing to impaired QPL and the main change in the wake of the COVID-19 pandemic. Conclusions: Female dermatologists reported heavier workloads. Heavy caseloads and more remote work were the main changes identified after the COVID-19 pandemic. Heavy caseloads have a significant impact on the QPL of dermatologists in Spain. Reducing caseloads would improve general job satisfaction and quality of care provision. Resumen: Antecedentes y objetivo: La calidad de vida profesional se define como el bienestar derivado del equilibrio entre las exigencias del ámbito laboral y los recursos para afrontarlas, el deterioro de la calidad de vida profesional puede contribuir en el síndrome de burnout o del profesional quemado. El objetivo de este estudio consiste en evaluar mediante cuestionario validado la calidad de vida profesional de los dermatólogos españoles. Material y métodos: Se diseñó un estudio transversal que incluyó dermatólogos españoles que respondieran a un formulario autoadministrado enviado a través de aplicaciones de mensajería online. El formulario incluyó datos sociodemográficos, 3 preguntas de respuestas abiertas y el Cuestionario de Calidad de Vida Profesional (CVP-35). Resultados: Se incluyó a 106 participantes en este estudio, siendo un 58% (62/106) mujeres. La edad media fue de 41 años (intervalo de confianza [IC] del 95%: 43,3-38,8). Las puntuaciones para el dominio «carga de trabajo» de CVP-35 fueron superiores en las mujeres (p = 0,02) y en los jefes de servicio (p = 0,005). La presión asistencial fue el tema tratado con más frecuencia como factor limitante de la calidad de vida laboral, y el principal cambio identificado tras la pandemia de COVID-19. Conclusiones: En nuestro estudio las mujeres refirieron una mayor carga de trabajo. El incremento de carga asistencial y de trabajo a distancia fueron los principales cambios por la pandemia de COVID-19. La presión asistencial es una gran limitante de la calidad de vida profesional de nuestros compañeros, reducirla mejoraría la satisfacción diaria y la calidad asistencial.
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- 2024
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20. Intramuscular ertapenem for the treatment of severe cases hidradenitis suppurativa
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Juan M. Segura Palacios, Alberto Soto Moreno, Ismael Valladares Millán, Francisco Rivas Ruiz, Carlos Cuenca Barrales, and Alejandro Molina Leyva
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Dermatology ,RL1-803 - Published
- 2023
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21. Short-Term Effectiveness, Safety, and Potential Predictors of Response of Secukinumab in Patients with Severe Hidradenitis Suppurativa Refractory to Biologic Therapy: A Multicenter Observational Retrospective Study
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Pablo Fernandez-Crehuet, Sofía Haselgruber, Alicia Padial-Gomez, Fiorella Vasquez-Chinchay, Maria Dolores Fernandez-Ballesteros, Irene López-Riquelme, David Jimenez-Gallo, Juan Manuel Segura-Palacios, Marisol Contreras-Steyls, Giovana Fernanda Osorio-Gómez, Juan Carlos Hernández-Rodríguez, Manuel Sanchez-Diaz, Carlos Cuenca-Barrales, Salvador Arias-Santiago, and Alejandro Molina-Leyva
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Hidradenitis suppurativa ,Secukinumab ,Anti-IL-17 ,Hidradenitis suppurativa clinical response ,HiSCR ,Therapeutic burden ,Dermatology ,RL1-803 - Abstract
Abstract Introduction Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease. Biologic drugs have a key role in the long-term anti-inflammatory treatment of moderate to severe patients due to their immunomodulatory properties. The aim of this study is to evaluate the effectiveness and safety of secukinumab in patients with moderate to severe HS after 16 weeks of treatment, and to explore potential predictors of clinical response to the drug. Methods Multicenter observational retrospective study. Patients treated with secukinumab 300 mg every 2 or 4 weeks who had completed at least 16 weeks of follow-up from nine hospitals based in southern Spain (Andalusia) were included in this study. Treatment effectiveness was assessed using the Hidradenitis Suppurativa Clinical Response (HiSCR). Information about adverse events was collected, the therapeutic burden of the patients was calculated as the summation of systemic medical treatments and surgical interventions (excluding incision and drainage) experienced until the start of secukinumab treatment. Results Forty-seven patients with severe HS were included for analysis. At week 16, 48.9% (23/47) of patients achieved HiSCR. Adverse events were present in 6.4% (3/47) of the patients. The multivariate analysis showed that female sex and, to a lesser extent, lower body mass index (BMI) and a lower therapeutic burden were potentially associated with a higher probability of HiSCR achievement. Conclusions Favorable short-term effectiveness and safety of secukinumab in the treatment of severe HS patients were observed. Female sex, lower BMI and a lower therapeutic burden may be associated with a higher probability of achieving HiSCR.
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- 2023
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22. Potential Predictors of Cardiovascular Risk Improvement in Patients with Hidradenitis Suppurativa Treated with Adalimumab: A Pivotal Study of Factors Associated with Carotid Intima–Media Thickness Reduction
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Manuel Sánchez-Díaz, Luis Salvador-Rodríguez, Carlos Cuenca-Barrales, Salvador Arias-Santiago, and Alejandro Molina-Leyva
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Cardiovascular risk ,Anti-TNF therapy ,Adalimumab ,Hidradenitis suppurativa ,Ultrasonography ,Dermatology ,RL1-803 - Abstract
Abstract Introduction Hidradenitis suppurativa (HS) has been linked to higher cardiovascular risk (CVR) due to its inflammatory burden. There is little evidence on how biologic treatment could modify the cardiovascular risk of patients with HS. The aims of the present study were to explore the modification of CVR in patients under adalimumab treatment and to explore the potential factors associated with CVR improvement. Methods A prospective longitudinal study was performed. A cohort of patients with HS treated with adalimumab was followed up. Carotid intima–media thickness (IMT) and other clinical and biochemical CVR factors were collected at baseline and 32 weeks after starting the treatment. Results Twenty-seven patients with severe HS were included. Overall, there were no differences in IMT between baseline (633 μm) and 32 weeks follow-up (634 μm). However, 40.7% (11/27) of the patients presented an improvement in IMT. This group (IMT responders) had a higher prevalence of dyslipidemia, diabetes mellitus, higher HbA1c levels, consumed more tobacco, and had higher BMI at baseline. Moreover, these patients had lower IHS4 scores at baseline and tended to have a greater IMT basal value, indicating a higher burden of subclinical atherosclerosis. Conclusions Adalimumab treatment might benefit a subset of patients with HS in terms of cardiovascular risk reduction. In light of the results of the present study patients with classical cardiovascular risk factors, and those with higher burden of subclinical atherosclerosis and with less inflammatory load, may be more likely to improve their IMT during adalimumab treatment.
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- 2023
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23. Factors Influencing Major Life-Changing Decisions in Patients with Psoriasis: A Cross-sectional Study
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Manuel Sanchez-Diaz, Pablo Díaz-Calvillo, Alberto Soto-Moreno, Alejandro Molina-Leyva, and Salvador Arias-Santiago
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Psoriasis ,Quality of life ,Life-Changing decision ,Dermatology ,RL1-803 - Abstract
Psoriasis is a chronic inflammatory disease associated with significant impairment in quality of life. Although quality of life in patients with psoriasis has been widely studied, there is little evidence regarding the impact of psoriasis on major life-changing decisions (MLCD). The aims of this study are to describe the impact of psoriasis on MLCD and to explore the potential clinical factors associated with MLCD. This cross-sectional study included 113 patients with psoriasis, regardless of disease severity, duration, or current treatment. The impact of the disease on different MLCD, including those related to professional career, decision of having children, choice of clothing, and leisure activities, was explored using Likert scales. Mean age was 51 years old and female to male ratio was 1.08 (54/50). The mean Psoriasis Area Severity Index was 3.75, and 30% (35/113) of the patients had psoriatic arthropathy. The most affected MLCD were career choice (median (interquartile range) score 3 (2–4)), social relationships (2 (1–3)), choice of clothing (2 (1–3)), job performance, absenteeism, and choice of holiday destination (1 (0–2)). Female sex, early age of onset and psoriatic arthropathy were associated with a greater impact of the disease on MLCD (p
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- 2023
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24. Pilonidal Sinus Disease is Associated with Severe Hidradenitis Suppurativa in a Spanish Cohort
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Clara Ureña-Paniego, Marta Gamissans-Cañada, Alejandro Molina-Leyva, and Jorge Romaní
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hidradenitis suppurativa ,epidemiology ,pilonidal sinus disease ,Dermatology ,RL1-803 - Abstract
Hidradenitis suppurativa is a chronic inflammatory disorder of the hair follicle with a high level of morbidity. Pilonidal sinus disease is a comorbid disorder and may be the reason for first contact with the healthcare system of patients with hidradenitis suppurativa. The aim of this study was to evaluate the frequency of association of pilonidal sinus disease and hidradenitis suppurativa and to explore whether pilonidal sinus disease defines a different clinical profile for patients with hidradenitis suppurativa. A cross-sectional study in which data regarding past history of pilonidal sinus disease, clinical and sociodemographic information were recorded during the first visit to the Hidradenitis Suppurativa Clinic of 2 tertiary hospitals. A total of 839 patients were included in the study. Of these, 51.7% (434/839) were male and mean age was 37.3 ± 13.6 years. Pilonidal sinus disease was present in 32.6% (269/839) of the patients and was associated with an early debut of hidradenitis suppurativa, a higher Hurley stage, inflammatory phenotype and a greater number of fistulas and perianal involvement. Elapsed time between pilonidal sinus disease and diagnosis of hidradenitis suppurativa was associated with higher disease severity. Pilonidal sinus disease is a frequent comorbidity and risk marker for hidradenitis suppurativa disease severity. Pilonidal sinus disease could be a sentinel event to identify patients who would benefit from close treatment and follow-up.
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- 2023
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25. ¿Cuánta carga asistencial suponen las infecciones de transmisión predominantemente sexual y otras dermatosis anogenitales en las consultas de Dermatología en España? Resultados del muestreo aleatorio nacional DIADERM
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A. Martin-Gorgojo, A. Comunión-Artieda, M.A. Descalzo-Gallego, S. Arias-Santiago, A. Molina-Leyva, Y. Gilaberte, P. Fernández-Crehuet, H. Husein-ElAhmed, A. Viera-Ramírez, P. Fernández-Peñas, R. Taberner, A. Buendía-Eisman, and I. García-Doval
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International Classification of Diseases, Tenth Revision (ICD-10) ,Outpatient clinics ,Services ,Outpatient health ,Sexually transmitted diseases ,Venereology ,Dermatology ,RL1-803 ,Internal medicine ,RC31-1245 - Abstract
Resumen: Introducción: Las infecciones e infestaciones de transmisión predominantemente sexual y otras dermatosis anogenitales forman parte de la formación específica de los médicos especialistas en Dermatología y Venereología en España. El presente estudio pretende analizar la carga que suponen dichas patologías en la actividad dermatológica pública y privada del sistema de salud español. Material y método: Estudio observacional de corte transversal de dos períodos de tiempo describiendo los diagnósticos realizados en consultas externas dermatológicas, obtenidos a través de la encuesta anónima DIADERM, realizada a una muestra aleatoria y representativa de dermatólogos. A partir de la codificación de diagnósticos CIE-10, se seleccionó toda la patología relacionada (36 diagnósticos codificados en los dos períodos), que se clasificó en 12 grupos. Resultados: Tan solo el 3,16% de los diagnósticos globales fueron de infecciones e infestaciones de transmisión predominantemente sexual y otras dermatosis anogenitales. Los 3 grupos diagnósticos más frecuentes fueron las lesiones por virus del papiloma humano anogenital, seguido de los molluscum contagiosum y las dermatosis anogenitales inflamatorias. Con significación estadística, y comparando con el global de diagnósticos, los seleccionados constituyeron más habitualmente el motivo de consulta primario y, en el ámbito privado, fue más frecuente que viniesen derivados de otros especialistas. Conclusión: Las infecciones e infestaciones de transmisión predominantemente sexual y otras dermatosis anogenitales tienen un peso muy limitado en la asistencia dermatológica en España, a pesar de que la inclusión del diagnóstico de molluscum contagiosum sobreestima estos diagnósticos. La ausencia de inclusión de centros y consultas monográficas de ITS en la muestra aleatoria contribuye a la infrarrepresentación de estas parcelas de la especialidad. Es importante hacer un esfuerzo decidido por potenciarlas con consultas y centros monográficos. Abstract: Background and objective: Predominantly sexually transmitted infections (STIs) and infestations and other anogenital dermatoses are covered in the training of specialists in dermatology and venereology in Spain. This study aimed to analyze the proportion of the dermatology caseload these diseases account for within the public and private dermatological activity of the Spanish health system. Material and methods: Observational cross-sectional study of time periods describing the diagnoses made in outpatient dermatology clinics, obtained through the anonymous DIADERM survey of a representative random sample of dermatologists. Based on diagnostic codes of the International Classification of Diseases, Tenth Revision, 36 related diagnoses were selected, and classified into 12 groups. Results: Only 3.16% of diagnoses corresponded to STIs and other anogenital dermatoses. The most common diagnostic group was anogenital human papillomavirus infection, followed by molluscum contagiosum, and inflammatory anogenital dermatoses. Lesions with these diagnoses were usually the main reasons for first visits in the National Health Service. In private practice, the diagnoses usually came after referrals from other physicians. Conclusions: STIs and other anogenital dermatoses account for a very small proportion of the dermatology caseload in Spain, although the inclusion of molluscum contagiosum diagnoses overestimates these conditions. The fact that no STI centers or monographic STI consultations were included in the random sample of dermatology partly explains the under-representation of these areas of the specialty. A determined effort to support and promote monographic STI centres and clinics should be made.
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- 2022
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26. Type D Personality as a Marker of Poorer Quality of Life and Mood Status Disturbances in Patients with Skin Diseases: A Systematic Review
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Manuel Sánchez-Díaz, Trinidad Montero-Vílchez, Maria I. Quiñones-Vico, Álvaro Sierra-Sánchez, Ana Ubago-Rodríguez, Raquel Sanabria-de la Torre, Alejandro Molina-Leyva, and Salvador Arias-Santiago
- Subjects
skin diseases ,quality of life ,anxiety ,depression ,type D personality ,Dermatology ,RL1-803 - Abstract
Type D personality is characterized by social inhibition and negative affectivity. Poorer outcomes and worse quality of life have been linked to type D personality in patients with a variety of non-dermatological diseases. Despite increasing evidence of the importance of type D personality in skin diseases, there are no reviews on this subject. The aim of this review is to summarize the current evidence regarding type D personality and skin diseases. A systematic search was performed using Medline and Web of Science databases from inception to 11 October 2022. Studies addressing the presence of type D personality, its associated factors, its impact on the outcomes of the disease or the quality of life of the patients were included in the systematic review. A total of 20 studies, including 3,124 participants, met the eligibility criteria and were included in the review. Acne, hidradenitis suppurativa, psoriasis, melanoma, atopic dermatitis, chronic spontaneous urticaria and pruritic disorders were the main diseases assessed. Type D personality was more frequent among patients with skin diseases than among controls. Type D personality was found to be associated with poorer quality of life and higher rates of psychological comorbidities in patients with skin diseases. In conclusion, type D personality appears to be a marker of patients with increased risk of poorer quality of life and higher rates of psychological comorbidities. Screening for type D personality in specialized dermatology units might be beneficial to identify patients who are more psychologically vulnerable to the consequences of chronic skin diseases.
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- 2023
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27. Four years stability of type D personality in patients with moderate to severe psoriasis and its implications for psychological impairment
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Paula Aguayo-Carreras, José Carlos Ruiz-Carrascosa, Ricardo Ruiz-Villaverde, and Alejandro Molina-Leyva
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Anxiety ,Depression ,Psoriasis ,Type D personality ,Dermatology ,RL1-803 - Abstract
Abstract Background: Psoriasis is a systemic auto-inflammatory disease that is related to an increased risk of organic and psychological comorbidities. Type D is a stable personality trait in healthy subjects but there is no data regarding its stability in patients with moderate-severe psoriasis. Objectives: To assess the stability of type D personality in patients with moderate to severe psoriasis as well as assessing the influence of type D personality on anxiety and depression. Methods: Prospective cohort study. Forty psoriasis patients with type D personality and sixtysix patients with psoriasis without type D personality were included in the study. Participants completed the DS14 test and HADS at baseline and four years later. Results: At baseline, the prevalence of type D personality was 37.7% and at week 208 it was 27.3%. The stability of type D personality was higher in patients with an incomplete education level and in those who were separated/divorced or windowed. During follow-up, 15% of patients developed type D personality. Male sex, having topical treatment, the presence of previous depression, anxiety, and high levels of negative affectivity at baseline increase the risk of developing type D personality. Study limitations: Sample size, psoriasis severity restricted to moderate and severe and all patients being under treatment for psoriasis. Conclusion The presence of type D personality varies over time in psoriasis patients. Therefore, type D personality is possibly more a state than a trait phenomenon, modified by environmental factors. Type D personality is associated with a higher risk of anxiety.
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- 2021
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28. Type D Personality Is Associated with Poorer Quality of Life in Patients with Chronic Spontaneous Urticaria: A Cross-sectional Study
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Manuel Sánchez-Díaz, Maria-Carmen Salazar-Nievas, Alejandro Molina-Leyva, and Salvador Arias-Santiago
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Urticaria ,Quality of life ,Type D personality ,Dermatology ,RL1-803 - Abstract
Type D personality (TDp) is a stable personality type that has been associated with poor quality of life in the general population and in patients with a variety of diseases, such as cancer, cardiac diseases, and dermatological diseases (e.g. psoriasis). To date, the potential association between chronic spontaneous urticaria and TDp has not been studied. The aim of this study is to analyse the impact of TDp on patients with chronic spontaneous urticaria, regarding mood disturbances, quality of life, sexuality, and sleep disturbances. A cross-sectional study including 75 patients with chronic spontaneous urticaria was performed. Data on socio- demographic variables and disease activity, quality of life, sleep, sexual dysfunction, anxiety, depression and TDp were collected using validated questionnaires. TDp was present in 28% (21/75) of the patients. Although TDp was not related to worse disease control, the presence of anxiety and depression was higher in patients with TDp. Regarding quality of life, TDp was associated with poorer quality of life and higher frequency of sleep disturbances. Prevalence of TDp in patients with chronic spontaneous urticaria is similar to that in the general population. It is associated with mood status disturbances and worse quality of life regardless of disease severity, especially in the emotional and psychological domains. This group of patients could benefit from additional psychological support as a complement to their medical treatment.
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- 2022
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29. Tofacitinib for Treatment of Alopecia Areata: Real-world Evidence and Factors Associated with Therapeutic Response
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Manuel Sanchez-Diaz, Pablo Diaz-Calvillo, Juan-Angel Rodriguez-Pozo, Jesús Tercedor-Sánchez, Maria-Rosa Cantudo-Cuenca, Alejandro Molina-Leyva, and Salvador Arias-Santiago
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Dermatology ,RL1-803 - Abstract
Abstract is missing (Short communication)
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- 2022
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30. [Translated article] Dermatology Care in Spanish Public Hospitals: A Mapping Study of Health Care Resources and Medical and Surgical Activity in Dermatology Departments in 2019
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C. Cuenca-Barrales, A. Molina-Leyva, D. Moreno-Ramírez, P. de la Cueva, Y. Gilaberte, and S. Arias-Santiago
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Dermatología ,Organización y Administración ,Investigación sobre servicios sanitarios ,Instalaciones, personal y servicios sanitarios ,Consultas externas ,Procedimientos quirúrgicos dermatológicos ,Dermatology ,RL1-803 ,Internal medicine ,RC31-1245 - Abstract
Background and objective: No recent data on health care resources and medical and surgical activity in Spanish dermatology departments are available in the literature. The aim of this study was to compile this information for 2019. Material and methods: Cross-sectional study based on an online survey sent to the heads of dermatology departments at public hospitals in Spain. Results: Of the 162 department heads contacted, 59 answered the survey (participation rate, 36.4%). General findings included a shortage of staff, especially dermatologists, in hospitals of low and medium complexity. The main reason given for the shortage of dermatologists was a lack of interested applicants. Large hospital complexes had more infrastructure and equipment. Over 50% of the departments surveyed used a combination of in-person and virtual visits. Psoriasis units were the most common specialized care units. Approximately 75% of the hospitals had operating rooms with an anesthetist. More complex procedures such as sentinel lymph node biopsy and Mohs micrographic surgery were performed more often in large hospital complexes. Hospitalization and the presence of dermatology residents working call shifts were also more common in these hospitals. Teaching and research activity differed according to hospital complexity. Conclusions: We have mapped health care resource availability and medical and surgical activity in Spanish dermatology departments prior to the COVID-19 pandemic. Our findings could be useful for improving clinical management and defining future actions and areas for improvement. Resumen: Antecedentes y objetivo: No existen datos actualizados sobre los recursos asistenciales ni la actividad médico-quirúrgica de los servicios de dermatología españoles. El objetivo de esta investigación es conocer la situación y actividad de dichos servicios durante el año 2019. Material y métodos: Estudio transversal mediante cuestionario online distribuido a los jefes de servicio de dermatología de hospitales públicos españoles. Resultados: De los 162 jefes de servicio encuestados, se obtuvo una participación del 36,4% (59/162). Se observó un déficit de personal generalizado, especialmente de dermatólogos en hospitales de complejidad media-baja. La principal causa del déficit de dermatólogos fue la ausencia de profesionales interesados. Las infraestructuras y equipamiento disponibles fueron superiores en los grandes complejos hospitalarios. La atención mixta presencial-telemática estuvo presente en más de la mitad de los centros. En el ámbito de las consultas monográficas, la de psoriasis fue la más implementada. Aproximadamente el 75% de los centros contaron con quirófanos con anestesista. Procedimientos quirúrgicos de mayor complejidad como la biopsia selectiva de ganglio centinela o la cirugía de Mohs se realizaban con mayor frecuencia en los grandes complejos hospitalarios. La hospitalización de pacientes y la presencia de dermatólogos residentes de guardia fue igualmente más habitual en estos hospitales. La actividad docente e investigadora también se relacionó con la complejidad del hospital. Conclusiones: Nuestros resultados describen la situación de los servicios de dermatología españoles justo antes de la pandemia por COVID-19, y pueden ser útiles para la gestión clínica y para definir líneas de trabajo y áreas de mejora.
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- 2022
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31. [Translated article] What Proportion of the Spanish Dermatology Caseload Corresponds to Primarily Sexually Transmitted Infections and Other Anogenital Dermatoses? Results From the DIADERM National Random Survey
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A. Martin-Gorgojo, A. Comunión-Artieda, M.Á. Descalzo-Gallego, S. Arias-Santiago, A. Molina-Leyva, Y. Gilaberte, P. Fernández-Crehuet, H. Husein-ElAhmed, A. Viera-Ramírez, P. Fernández-Peñas, R. Taberner, A. Buendía-Eisman, and I. García-Doval
- Subjects
Clasificación Internacional de Enfermedades, CIE-10 ,Consulta externa hospitalaria ,Actividad ambulatoria ,Dermatología ,Enfermedades de transmisión sexual ,Venereología ,Dermatology ,RL1-803 ,Internal medicine ,RC31-1245 - Abstract
Background and objective: Predominantly sexually transmitted infections (STIs) and infestations and other anogenital dermatoses are covered in the training of specialists in dermatology and venereology in Spain. This study aimed to analyze the proportion of the dermatology caseload these diseases account for within the public and private dermatological activity of the Spanish health system. Material and methods: Observational cross-sectional study of time periods describing the diagnoses made in outpatient dermatology clinics, obtained through the anonymous DIADERM survey of a representative random sample of dermatologists. Based on diagnostic codes of the International Classification of Diseases, Tenth Revision, 36 related diagnoses were selected, and classified into 12 groups. Results: Only 3.16% of diagnoses corresponded to STIs and other anogenital dermatoses. The most common diagnostic group was anogenital human papillomavirus infection, followed by molluscum contagiosum, and inflammatory anogenital dermatoses. Lesions with these diagnoses were usually the main reasons for first visits in the National Health Service. In private practice, the diagnoses usually came after referrals from other physicians. Conclusions: STIs and other anogenital dermatoses account for a very small proportion of the dermatology caseload in Spain, although the inclusion of molluscum contagiosum diagnoses overestimates these conditions. The fact that no STI centers or monographic STI consultations were included in the random sample of dermatology partly explains the under-representation of these areas of the specialty. A determined effort to support and promote monographic STI centres and clinics should be made. Resumen: Introducción: Las infecciones e infestaciones de transmisión predominantemente sexual y otras dermatosis anogenitales forman parte de la formación específica de los médicos especialistas en Dermatología y Venereología en España. El presente estudio pretende analizar la carga que suponen dichas patologías en la actividad dermatológica pública y privada del sistema de salud español. Material y método: Estudio observacional de corte transversal de dos períodos de tiempo describiendo los diagnósticos realizados en consultas externas dermatológicas, obtenidos a través de la encuesta anónima DIADERM, realizada a una muestra aleatoria y representativa de dermatólogos. A partir de la codificación de diagnósticos CIE-10, se seleccionó toda la patología relacionada (36 diagnósticos codificados en los dos períodos), que se clasificó en 12 grupos. Resultados: Tan solo el 3,16% de los diagnósticos globales fueron de infecciones e infestaciones de transmisión predominantemente sexual y otras dermatosis anogenitales. Los 3 grupos diagnósticos más frecuentes fueron las lesiones por virus del papiloma humano anogenital, seguido de los molluscum contagiosum y las dermatosis anogenitales inflamatorias. Con significación estadística, y comparando con el global de diagnósticos, los seleccionados constituyeron más habitualmente el motivo de consulta primario y, en el ámbito privado, fue más frecuente que viniesen derivados de otros especialistas. Conclusión: Las infecciones e infestaciones de transmisión predominantemente sexual y otras dermatosis anogenitales tienen un peso muy limitado en la asistencia dermatológica en España, a pesar de que la inclusión del diagnóstico de molluscum contagiosum sobreestima estos diagnósticos. La ausencia de inclusión de centros y consultas monográficas de ITS en la muestra aleatoria contribuye a la infrarrepresentación de estas parcelas de la especialidad. Es importante hacer un esfuerzo decidido por potenciarlas con consultas y centros monográficos.
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- 2022
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32. Neoadjuvant Biologic Therapy in the Surgical Management of Patients with Hidradenitis Suppurativa: A Cohort Study
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Luis Salvador-Rodriguez, Carlos Cuenca-Barrales, Salvador Arias-Santiago, and Alejandro Molina-Leyva
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acne inversa ,biological therapy ,hidradenitis suppurativa ,surgery ,therapeutics ,Dermatology ,RL1-803 - Abstract
Abstract is missing (Short communication)
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- 2020
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33. Epidermodysplasia verruciformis and breast cancer - Casual or Causal?
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Trinidad Montero-Vilchez, Antonio Martinez-Lopez, Andrea Rodriguez-Tejero, Jesus Tercedor-Sanchez, Alejandro Molina-Leyva, and Salvador Arias-Santiago
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Dermatology ,RL1-803 - Published
- 2022
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34. Necrólisis epidérmica tóxica versus enfermedad injerto contra huésped cutánea aguda después de un trasplante de células madre hematopoyéticas: un desafío diagnóstico y terapéutico
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A. Rodríguez Tejero, J. Badiola González, L. Roldán Mateo, and A. Molina Leyva
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Dermatology ,RL1-803 ,Internal medicine ,RC31-1245 - Published
- 2021
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35. Prevalence and implications of type D personality in patients with alopecia areata: A marker of quality‐of‐life impairment and mood status disturbances, a comparative study
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Manuel Sánchez‐Díaz, Trinidad Montero‐Vílchez, Carlos Cuenca‐Barrales, Alejandro Molina‐Leyva, and Salvador Arias‐Santiago
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Infectious Diseases ,Dermatology - Abstract
Distressed personality (or Type D personality, TDp) is a personality trait that has been associated with poor quality of life in patients suffering from a variety of skin diseases such as psoriasis or urticaria. To date the potential association between Alopecia areata (AA) and TDp has not been studied. The aim of this study was to compare the prevalence of TDp between patients with AA and controls, and to analyse the impact of TDp on patients with AA regarding mood status disturbances, quality of life and sexuality.Cross-sectional study includes patients suffering from mild-to-severe AA and sex- and age-matched healthy controls. Socio-demographic and clinical variables, quality of life, sexual disfunction, anxiety, depression and TDp were collected using validated questionnaires.A total of 120 participants (60 patients and 60 controls) were included. Patients with AA showed higher prevalence of TDp than controls (35% vs. 15% p = 0.01), as well as higher rates of anxiety, depression and sexual dysfunction (p 0.05). TDp was found to be linked to disease severity (p = 0.04), anxiety and depression scores (p 0.001) and worse quality of life (p = 0.001). No relationship was found between TDp and sexual dysfunction.Type D personality prevalence is higher in patients with AA than in controls. It is associated with higher rates of anxiety, depression and worse quality of life. Screening for this type of personality could be useful to detect patients who could benefit from additional psychological support as a complement to their medical treatment.
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- 2022
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36. Can Ultrasound Examinations Generate Pain in Hidradenitis Suppurativa Patients? Results from a Multicentric Cross-Sectional Study
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Ximena Wortsman, Francisco Reyes-Baraona, Cristian Ramirez-Cornejo, Camila Ferreira-Wortsman, Raffaele Dante Caposiena Caro, Alejandro Molina-Leyva, Salvador Arias-Santiago, Priscila Giavedoni, Antonio Martorell, Jorge Romani, Claudia Gonzalez, and Fernando Alfageme
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Dermatology - Abstract
Background: Pain is not a trivial issue for hidradenitis suppurativa (HS) patients and has been considered a domain in the Core Outcome Set. To date, there is no evidence about pain caused by the ultrasound examinations. Objective: The aim of the study was to assess the presence of pain generated by the ultrasound examinations of HS patients. Methods: A multicentric cross-sectional study for detecting pain during the ultrasound examinations of HS patients using a validated verbal questionnaire immediately after the imaging studies. Statistical analysis included demographic data and possible associations with sex, age, location, clinical (Hurley), and ultrasonographic scoring (SOS-HS). The statistical tests were two proportions Z test, χ2 test, Student’s t test, and ANOVA. A p < 0.05 was considered significant. Results: 317 patients met the criteria. 77.3% of them did not present pain. Of cases with pain, 59.8% were mild, 16.7% moderate, and 23.6% severe. No significant association was found with sex, age, staging, location, or the number of affected regions. Although nonsignificant, severe pain cases were more frequent in the clinical Hurley III and ultrasonographic SOS-HS III stages. Conclusion: Pain generated by the ultrasound examination of HS patients is infrequent.
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- 2022
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37. Distribution pattern of psoriasis, anxiety and depression as possible causes of sexual dysfunction in patients with moderate to severe psoriasis
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Alejandro Molina-Leyva, Ana Almodovar-Real, Jose Carlos-Ruiz Carrascosa, Ignacio Molina-Leyva, Ramon Naranjo-Sintes, and Jose Juan Jimenez-Moleon
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Anxiety ,Case-control studies ,Depression ,Psoriasis ,Sexual dysfunctions, psychological ,Dermatology ,RL1-803 - Abstract
Abstract BACKGROUND: Psoriasis may significantly impair sexual function. Depression and organic factors appear to play a key role in this relation. However, beyond genital psoriasis, the importance of the disease's distribution patterns has not been considered. OBJECTIVES: To research sexual function in psoriasis patients and investigate the roles of anxiety, depression and psoriasis' distribution patterns in sexual dysfunction. METHODS: A comparative study matched for sex and age was performed. Eighty patients with moderate to severe psoriasis and 80 healthy controls were included. The participants completed the Massachusetts General Hospital-Sexual Functioning Questionnaire, the Hospital Anxiety and Depression Scale, and the Self-Administered Psoriasis Area and Severity Index. RESULTS: Psoriasis was associated with sexual dysfunction, odds ratio=5.5 (CI 95% 2.6-11.3; p
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- 2015
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38. Effectiveness and Safety of Acitretin for the Treatment of Hidradenitis Suppurativa, Predictors of Clinical Response: A Cohort Study
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Manuel Sánchez-Díaz, Pablo Díaz-Calvillo, Juan Ángel Rodríguez-Pozo, Salvador Arias-Santiago, and Alejandro Molina-Leyva
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Dermatology - Abstract
Background: Hidradenitis suppurativa (HS) is a chronic inflammatory disease of the hair follicle which presents with painful nodules, abscesses, and fistulae in apocrine gland-bearing areas of the skin. Approved treatments include antibiotics and biologic drugs such as adalimumab. Despite these treatments, HS management is challenging. Acitretin is an oral retinoid used for its management as 3rd or 4th line therapy. There is little evidence regarding the effectiveness and safety of acitretin treatment for HS, and no reports have previously explored the potential clinical predictors associated with the response to the treatment. Methods: Retrospective cohort study to assess the effectiveness and safety of acitretin treatment in HS patients who failed to respond to topical therapies. Results: Sixty-two patients with moderate to severe HS were included. A significant decrease in the International HS Severity Scoring System (IHS4) score was found over time. Higher basal IHS4 score, family history of HS, follicular phenotype, and history of follicular plugging conditions were potential predictors of response. Most patients did not suffer any adverse events, and no severe side effects were observed. The main cause of discontinuation was lack of efficacy. Conclusion: Acitretin can be considered as a therapeutic option for patients with HS. The presence of follicular phenotype or a history of components of follicular occlusion syndrome is associated with better outcomes.
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- 2022
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39. The impact of dupilumab on skin barrier function: A systematic review
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Trinidad Montero‐Vilchez, Raquel Sanabria‐de‐la‐Torre, Manuel Sanchez‐Diaz, Clara Ureña‐Paniego, Alejandro Molina‐Leyva, and Salvador Arias‐Santiago
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Infectious Diseases ,Dermatology - Published
- 2023
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40. Risk factors of quality-of-life and sexual function impairment in chronic spontaneous urticaria patients: cross-sectional study
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Manuel Sánchez-Díaz, Maria Carmen Salazar-Nievas, Alejandro Molina-Leyva, and Salvador Arias-Santiago
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Dermatology - Abstract
Background: Chronic spontaneous urticaria (CSU) has been associated with poor quality of life and mood disturbances. However, factor associated to these dimensions have not been properly assessed. Moreover, there is a lack of studies regarding sexual dysfunction (SD) and CSU. Therefore, the aims of this study are to assess quality of life associated factors and to evaluate the prevalence and potential impact of SD in patients with CSU. Method: Cross-sectional study of patients suffering from CSU. Socio-demographic and disease activity variables, quality of life, sleep, SD, anxiety and depression were collected using validated questionnaires. Results: Seventy-five patients were included, with a female to male ratio of 2.40. Female sex, worse disease control, and sexual dysfunction were associated with poor quality-of-life indexes (p
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- 2023
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41. Epidermodysplasia Verruciformis and Breast Cancer - Casual or Causal?
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Alejandro Molina-Leyva, Trinidad Montero-Vilchez, Antonio Martinez-Lopez, Andrea Rodriguez-Tejero, Jesus Tercedor-Sanchez, Salvador Arias-Santiago, [Montero-Vilchez, Trinidad] Hosp Univ Virgen de las Nieves, Dept Dermatol, Granada, Spain, [Martinez-Lopez, Antonio] Hosp Univ Virgen de las Nieves, Dept Dermatol, Granada, Spain, [Rodriguez-Tejero, Andrea] Hosp Univ Virgen de las Nieves, Dept Dermatol, Granada, Spain, [Tercedor-Sanchez, Jesus] Hosp Univ Virgen de las Nieves, Dept Dermatol, Granada, Spain, [Molina-Leyva, Alejandro] Hosp Univ Virgen de las Nieves, Dept Dermatol, Granada, Spain, [Arias-Santiago, Salvador] Hosp Univ Virgen de las Nieves, Dept Dermatol, Granada, Spain, [Montero-Vilchez, Trinidad] Inst Invest Biosanitaria Ibs Granada, Granada, Spain, [Martinez-Lopez, Antonio] Inst Invest Biosanitaria Ibs Granada, Granada, Spain, [Rodriguez-Tejero, Andrea] Inst Invest Biosanitaria Ibs Granada, Granada, Spain, [Tercedor-Sanchez, Jesus] Inst Invest Biosanitaria Ibs Granada, Granada, Spain, [Molina-Leyva, Alejandro] Inst Invest Biosanitaria Ibs Granada, Granada, Spain, [Arias-Santiago, Salvador] Inst Invest Biosanitaria Ibs Granada, Granada, Spain, [Montero-Vilchez, Trinidad] Univ Granada, Fac Med, Granada, Spain, [Martinez-Lopez, Antonio] Univ Granada, Fac Med, Granada, Spain, [Rodriguez-Tejero, Andrea] Univ Granada, Fac Med, Granada, Spain, [Tercedor-Sanchez, Jesus] Univ Granada, Fac Med, Granada, Spain, [Molina-Leyva, Alejandro] Univ Granada, Fac Med, Granada, Spain, and [Arias-Santiago, Salvador] Univ Granada, Fac Med, Granada, Spain
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Dermatology - Published
- 2022
42. Proliferative nodule in melanocytic nevi mimicking deep penetrating nevus
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Ana Almodovar-Real, Alejandro Molina-Leyva, Jose Aneiros-Fernandez, and Miguel Antonio Diaz-Martinez
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Diagnosis ,Nevus, pigmented ,Pathology ,Dermatology ,RL1-803 - Abstract
Abstract: Proliferative nodules can occasionally arise on congenital and acquired melanocytic nevi. At first sight their clinical and pathologic features cause alert to both dermatologist and dermatopathologist. However, proliferative nodules are typically benign, regression is common and there is minimum risk of malignization. We present a new case of proliferative nodule in melanocytic nevi with features of deep penetrating nevus.
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- 2017
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43. ¿Cuánta carga asistencial suponen las infecciones de transmisión predominantemente sexual y otras dermatosis anogenitales en las consultas de Dermatología en España? Resultados del muestreo aleatorio nacional DIADERM
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M.A. Descalzo-Gallego, Pablo Fernández-Crehuet, Alejandro Martin-Gorgojo, Agustín Buendía-Eisman, A. Comunión-Artieda, R. Taberner, Ignacio García-Doval, Pablo Fernandez-Penas, Yolanda Gilaberte, S. Arias-Santiago, Alejandro Molina-Leyva, Husein Husein-ElAhmed, and A. Viera-Ramírez
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Sexually transmitted diseases ,Venereology ,business.industry ,International Classification of Diseases, Tenth Revision (ICD-10) ,CIE-10 ,Services ,Dermatología ,General Medicine ,Actividad ambulatoria ,Dermatology ,Outpatient health ,RC31-1245 ,Outpatient clinics ,RL1-803 ,Medicine ,Outpatient clinic ,business ,Consulta externa hospitalaria ,Humanities ,Clasificación Internacional de Enfermedades ,Internal medicine ,Enfermedades de transmisión sexual ,Venereología - Abstract
El estudio DIADERM fue promovido por la Fundacion Piel Sana de la AEDV, que recibio ayuda economica de Novartis. La compania farmaceutica no participo en la recogida de datos, ni en el analisis de los datos, ni en la interpretacion de los resultados., Introducción: Las infecciones e infestaciones de transmisión predominantemente sexual y otras dermatosis anogenitales forman parte de la formación específica de los médicos especialistas en Dermatología y Venereología en España. El presente estudio pretende analizar la carga que suponen dichas patologías en la actividad dermatológica pública y privada del sistema de salud español. Material y método: Estudio observacional de corte transversal de dos períodos de tiempo describiendo los diagnósticos realizados en consultas externas dermatológicas, obtenidos a través de la encuesta anónima DIADERM, realizada a una muestra aleatoria y representativa de dermatólogos. A partir de la codificación de diagnósticos CIE-10, se seleccionó toda la patología relacionada (36 diagnósticos codificados en los dos períodos), que se clasificó en 12 grupos. Resultados: Tan solo el 3,16% de los diagnósticos globales fueron de infecciones e infestaciones de transmisión predominantemente sexual y otras dermatosis anogenitales. Los 3 grupos diagnósticos más frecuentes fueron las lesiones por virus del papiloma humano anogenital, seguido de los molluscum contagiosum y las dermatosis anogenitales inflamatorias. Con significación estadística, y comparando con el global de diagnósticos, los seleccionados constituyeron más habitualmente el motivo de consulta primario y, en el ámbito privado, fue más frecuente que viniesen derivados de otros especialistas. Conclusión: Las infecciones e infestaciones de transmisión predominantemente sexual y otras dermatosis anogenitales tienen un peso muy limitado en la asistencia dermatológica en España, a pesar de que la inclusión del diagnóstico de molluscum contagiosum sobreestima estos diagnósticos. La ausencia de inclusión de centros y consultas monográficas de ITS en la muestra aleatoria contribuye a la infrarrepresentación de estas parcelas de la especialidad. Es importante hacer un esfuerzo decidido por potenciarlas con consultas y centros monográficos., Background and objective: Predominantly sexually transmitted infections (STIs) and infestations and other anogenital dermatoses are covered in the training of specialists in dermatology and venereology in Spain. This study aimed to analyze the proportion of the dermatology caseload these diseases account for within the public and private dermatological activity of the Spanish health system. Material and methods: Observational cross-sectional study of time periods describing the diagnoses made in outpatient dermatology clinics, obtained through the anonymous DIADERM survey of a representative random sample of dermatologists. Based on diagnostic codes of the International Classification of Diseases, Tenth Revision, 36 related diagnoses were selected, and classified into 12 groups. Results: Only 3.16% of diagnoses corresponded to STIs and other anogenital dermatoses. The most common diagnostic group was anogenital human papillomavirus infection, followed by molluscum contagiosum, and inflammatory anogenital dermatoses. Lesions with these diagnoses were usually the main reasons for first visits in the National Health Service. In private practice, the diagnoses usually came after referrals from other physicians. Conclusions: STIs and other anogenital dermatoses account for a very small proportion of the dermatology caseload in Spain, although the inclusion of molluscum contagiosum diagnoses overestimates these conditions. The fact that no STI centers or monographic STI consultations were included in the random sample of dermatology partly explains the under-representation of these areas of the specialty. A determined effort to support and promote monographic STI centres and clinics should be made., Fundacion Piel Sana de la AEDV
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- 2022
44. Fears, concerns and expectations in dermatologic emergencies: A qualitative and descriptive study in a tertiary hospital
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Alberto Soto‐Moreno, Clara Ureña‐Paniego, Trinidad Montero‐Vílchez, Manuel Sánchez‐Díaz, Pablo Díaz‐Calvillo, Juan Ángel Rodríguez‐Pozo, Alejandro Molina‐Leyva, Antonio Martínez‐López, and Salvador Arias‐Santiago
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Infectious Diseases ,Dermatology - Published
- 2023
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45. External validation of the IHS4-55 in a European antibiotic-treated HS cohort
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Kelsey R. van Straalen, Thrasyvoulos Tzellos, Afsaneh Alavi, Farida Benhadou, Carlos Cuenca-Barrales, Mathilde Daxhelet, Mathieu Daoud, Ourania Efthymiou, Evangelos J. Giamarellos-Bourboulis, Philippe Guillem, Wayne Gulliver, Gregor Borut Ernst Jemec, Alexandros Katoulis, Anke Koenig, Elizabeth Lazaridou, Michelle A. Lowes, Angelo V. Marzano, Łukasz Matusiak, Alejandro Molina-Leyva, Chiara Moltrasio, Andreas Pinter, Concetta Potenza, Errol P. Prens, Jorge Romaní, Ditte Marie L. Saunte, Christopher J Sayed, Nevena Skroza, Dimitra Stergianou, Jacek C. Szepietowski, Anastasia Trigoni, Eva Vilarrasa, Athanassios Kyrgidis, Christos C. Zouboulis, and Hessel H. van der Zee
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Dermatology - Abstract
Background: Previously, a new dichotomous outcome was developed, calculated as 55% reduction in the International Hidradenitis Suppurativa 4 score (IHS4-55). It was validated in datasets of adalimumab and placebo treated HS patients. External validation is an important aspect of clinical outcomes. Objectives: We aimed to externally validate the novel dichotomous IHS4-55 in a non-biologic treated dataset of HS patients. Methods: Data from a previously published European-wide prospective clinical study of antibiotic treatment of HS patients was used to assess the association of IHS4-55 achievement with individual reduction in inflammatory nodules, abscesses and draining tunnels. Moreover, the associations between IHS4-55 positivity and achievement of the minimal clinically important differences (MCID) for Dermatology Life Quality Index (DLQI), numerical rating scale (NRS) Pain, and NRS Pruritus were analyzed. Results: Data was obtained from 283 individual patients, of which 36.4% (103/283) were treated with clindamycin and rifampicin and 63.6% (180/283) with tetracyclines for 12 weeks. Achievers of the IHS4-55 demonstrated a significant reduction the counts of inflammatory nodules, abscesses, and draining tunnels (all p
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- 2023
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46. Queilitis de Miescher, diagnóstico de exclusión y revisión de las opciones terapéuticas
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David López-Delgado, Salvador Arias-Santiago, Alejandro Molina-Leyva, Andrea Rodriguez-Tejero, Manuel Sánchez-Díaz, and Luis Salvador-Rodriguez
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business.industry ,Medicine ,Dermatology ,business - Published
- 2021
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47. Specialized Dermatology Training in Spain: Opinions of 53 Third-Year Dermatology Residents Surveyed in 2019
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T. Montero-Vilchez, A. Molina-Leyva, A. Martinez-Lopez, A. Buendia-Eisman, R. Ortega-Olmo, S. Serrano-Ortega, and S. Arias-Santiago
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Histology ,Dermatology ,Pathology and Forensic Medicine - Published
- 2021
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48. Itchy Capillary Malformations: Unusual Appearance of Meyerson Phenomenon, a Case Series
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Jesús Tercedor-Sánchez, Manuel Sánchez-Díaz, Luis Salvador-Rodriguez, Trinidad Montero-Vilchez, Alejandro Molina-Leyva, Salvador Arias-Santiago, [Sanchez-Diaz,M, Montero-Vilchez,T, Salvador-Rodriguez,L, Molina-Leyva,A, Arias-Santiago,S, and Tercedor-Sanchez,J] Dermatology Unit, IBS Granada, Hospital Universitario Virgen de las Nieves, Granada, Spain. [Arias-Santiago,S] Granada School of Medicine, Granada University, Granada, Spain. [Tercedor-Sanchez,J] Pediatric Dermatology Unit, IBS Granada, Hospital Universitario Virgen de las Nieves, Granada, Spain.
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medicine.medical_specialty ,Capillary malformation ,Malformaciones vasculares ,Neoplasias cutáneas ,Eczema ,lcsh:Medicine ,Case Report ,Vascular malformation ,Topical treatment ,Eccema ,Pediatrics ,Diseases::Skin and Connective Tissue Diseases::Skin Diseases::Skin Neoplasms [Medical Subject Headings] ,vascular malformation ,Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnosis, Differential [Medical Subject Headings] ,030207 dermatology & venereal diseases ,03 medical and health sciences ,0302 clinical medicine ,Diseases::Skin and Connective Tissue Diseases::Skin Diseases::Dermatitis::Eczema [Medical Subject Headings] ,medicine ,Pediatras ,Persons::Persons::Age Groups::Child [Medical Subject Headings] ,Pediatric dermatology ,Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Errors [Medical Subject Headings] ,Persons::Persons::Age Groups::Infant [Medical Subject Headings] ,business.industry ,capillary malformation ,lcsh:R ,Disciplines and Occupations::Health Occupations::Medicine::Dermatology [Medical Subject Headings] ,lcsh:RJ1-570 ,Dermatología ,Diseases::Skin and Connective Tissue Diseases::Skin Diseases::Pruritus [Medical Subject Headings] ,lcsh:Pediatrics ,Chemicals and Drugs::Hormones, Hormone Substitutes, and Hormone Antagonists::Hormones::Adrenal Cortex Hormones [Medical Subject Headings] ,medicine.disease ,Meyerson ,Dermatology ,030220 oncology & carcinogenesis ,Diseases::Bacterial Infections and Mycoses::Mycoses [Medical Subject Headings] ,eczema ,Differential diagnosis ,Hemangioma ,Skin lesion ,business - Abstract
Meyerson phenomenon, also known as “halo-eczema,” has been widely described over melanocytic and non-melanocytic lesions. However, its appearance over vascular anomalies is rarely observed and could lead to diagnostic errors. A case study of five patients aged between four months and two years is reported. These patients developed unique erythematous and pruritic scaly patches, being diagnosed and treated as fungal infections. Due to the lack of response to the treatment, they were referred to the pediatric dermatology practice, where the diagnosis of Meyerson phenomenon over capillary malformations was made. Topical treatment with corticosteroids led to improvement in all cases. Although Meyerson phenomenon developing over vascular anomalies is a rare condition, it is important for pediatricians and dermatologists to assess it as a part of the differential diagnosis when treating a patient with skin lesions. Recognizing this phenomenon will prevent diagnostic and therapeutic errors.
- Published
- 2021
49. Neonatal epidermolysis bullosa, step-by-step diagnostic procedure
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Jesús Tercedor Sánchez, Alejandro Molina Leyva, Salvador Arias-Santiago, and Andrea Rodríguez Tejero
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medicine.medical_specialty ,business.industry ,medicine ,Dermatology ,Epidermolysis bullosa ,medicine.disease ,business - Published
- 2021
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50. The efficacy and tolerability of tetracyclines and clindamycin plus rifampicin for the treatment of hidradenitis suppurativa
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van Straalen, Kelsey R., Tzellos, Thrasyvoulos, Guillem, Phillipe, Benhadou, Farida, Cuenca-Barrales, Carlos, Daxhelet, Mathilde, Daoud, Mathieu, Efthymiou, Ourania, Giamarellos-Bourboulis, Evangelos J., Jemec, Gregor B.E., Katoulis, Alexandros C., Koenig, Anke, Lazaridou, Elizabeth, Marzano, Angelo V., Matusiak, Łucas, Molina-Leyva, Alejandro, Moltrasio, Chiara, Pinter, Andreas, Potenza, Concetta, Romaní, Jorge, Saunte, Ditte M., Skroza, Nevena, Stergianou, Dimitra, Szepietowski, Jacek, Trigoni, Anastasia, Vilarrasa-Rull, Eva, van der Zee, Hessel H., Universitat Autònoma de Barcelona, and Dermatology
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Adult ,Male ,medicine.medical_specialty ,Combination therapy ,efficacy ,acne inversa ,antibiotics ,clindamycin ,doxycycline ,guideline ,minocycline ,outcome ,rifampicin ,tetracycline ,therapy ,treatment ,Clindamycin ,Cohort Studies ,Drug Combinations ,Europe ,Female ,Hidradenitis Suppurativa ,Humans ,Middle Aged ,Prospective Studies ,Rifampin ,Tetracyclines ,Treatment Outcome ,Dermatology ,030207 dermatology & venereal diseases ,03 medical and health sciences ,0302 clinical medicine ,Internal medicine ,medicine ,Hidradenitis suppurativa ,ddc:610 ,business.industry ,Minocycline ,Dermatology Life Quality Index ,Sciences bio-médicales et agricoles ,medicine.disease ,Tolerability ,030220 oncology & carcinogenesis ,business ,Rifampicin ,medicine.drug ,Cohort study - Abstract
Tetracyclines and clindamycin plus rifampicin combination therapy are both considered first-line therapy in current Hidradenitis Suppurativa (HS) guidelines. However, evidence for their efficacy is drawn from small studies, often without validated outcomes., info:eu-repo/semantics/published
- Published
- 2021
- Full Text
- View/download PDF
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