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Objective: Previous studies showed that nocturia has a negative effect on patients' sleep quality. However, studies that focused on the sleep quality of patients' partners are limited. In this study, we evaluated the impact of nocturia on sleep quality in patients with benign prostatic obstruction (BPO) and their female partners. Materials and Methods: We included 50 BPO patients with nocturia (group 1), 50 patients without nocturia (group 2) and their female partners. Lower urinary tract symptoms of the patients were evaluated by international prostate symptom score, serum prostate-specific antigen, uroflowmetry and urinary ultrasonography. The sleep quality of the patients and their partners were assessed by Pittsburgh sleep quality index (PSQI). The demographic and evaluation outcomes of the participants were recorded. Results: The mean age of the patients and their partners were 63±7.9 and 57.4±8.5 years, respectively, with no statistical significance. The patients and their partners in group 1 had significantly higher global PSQI compared with those in group 2. The percentage of poor sleep in patients and partners in group 1 was higher than that in group 2. Conclusion: Nocturia negatively affects the sleep quality of patients with BPO and their partners. [ABSTRACT FROM AUTHOR] more...

Objective: The aim of the present study was to evaluate whether thyroid hormone levels in benign thyroid disorders resulting in hypothyroidism or hyperthyroidism had an impact on the levels of serum prostate specific antigen (PSA). Materials and Methods: A total of 50 male patients aged between 40 and 75 years who had newly diagnosed benign thyroid disorders were enrolled in this study. Patients with hypothyroidism (n=19) were enrolled as group 1 and patients with hyperthyroidism (n=31) as group 2. Before the initiation of medical treatment, levels of serum total, free PSA, and thyroid hormones were measured. Patients then received appropriate medical treatment for their thyroid disease. Once patients were noted to have achieved normal thyroid function tests in the second month following treatment initiation, serum total and free PSA levels were once again measured. Results: The mean age of the patients was 56.7 years. The mean pretreatment serum total PSA levels in group 1 and 2 were 1.5 and 2.6 ng/mL, respectively (p=0.03). Although group 1 patients had lower posttreatment mean serum total PSA levels (1.7 ng/mL) compared to group 2 (2.5 ng/mL), the difference was not statistically significant (p=0.15). In the comparisons of pre and posttreatment serum total PSA, free PSA and free/total PSA (%) levels in both groups, no statistically significant difference was found (p>0.05). Conclusion: Our results showed that decreased serum thyroid stimulating hormone and increased serum T3 and T4 levels were associated with increased serum PSA levels. It was also observed that there was no alteration in serum PSA level in relationship to medical treatment received. [ABSTRACT FROM AUTHOR] more...