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3 results on '"Xing, Shan"'

1. Clinical Significance of Preoperative Albumin and Globulin Ratio in Patients with Gastric Cancer Undergoing Treatment.

Author

Mao, Min-jie, Wei, Xiao-li, Sheng, Hui, Wang, Xue-ping, Li, Xiao-hui, Liu, Yi-jun, Xing, Shan, Huang, Qi, Dai, Shu-qin, and Liu, Wan-li

Subjects
*CHI-squared test, *CONFIDENCE intervals, *GLOBULINS, *STATISTICAL hypothesis testing, *STOMACH tumors, *ALBUMINS, *PROPORTIONAL hazards models, *RETROSPECTIVE studies, *DATA analysis software, *DESCRIPTIVE statistics, *KAPLAN-Meier estimator, *LOG-rank test
Abstract

Background. The pretreatment albumin and globulin ratio (AGR) was an inflammation-associated factor which was related to the overall survival in various malignancies. The aim of this study was to evaluate the prognostic value of AGR in patients with gastric cancer. Method. This retrospective study included 862 cases pathologically diagnosed with gastric cancer. All patients were randomly divided into the testing group (431 cases) and validation group (431 cases). The relationships of AGR with clinicopathologic characteristics and prognosis were analyzed by Kaplan-Meier and Cox regression methods. Results. In the testing group, the median overall survival was 26.90 months and the cutoff value of AGR was 1.50 based on R language. Kaplan-Meier analysis showed that lower AGR was correlated with poorer overall survival. Multivariate analysis demonstrated that AGR was an independent prognostic factor for overall survival (HR: 0.584, 95% CI = 0.351–0.973, and p = 0.039). In the validation group, the median overall survival was 24.10 months. Lower AGR (≤1.50) also had a significantly poorer overall survival by Kaplan-Meier analysis. According to multivariate analysis, the AGR was also confirmed to be an independent prognostic factor for overall survival (HR: 0.578, 95% CI = 0.373–0.897, and p = 0.015). Conclusions. Our study suggested that the pretreatment AGR could be a prognostic biomarker for overall survival in patients with gastric cancer. [ABSTRACT FROM AUTHOR]

Published
2017
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2. Two new lignans from Saururus chinensis and their DGAT inhibitory activity.

Author

Li, Na, Tuo, Zhen-Dong, Qi, Shi-Zhou, Xing, Shan-Shan, Lee, Hyun-Sun, Chen, Jian-Guang, and Cui, Long

Subjects
*ALTERNATIVE medicine, *PHYSICAL & theoretical chemistry, *DOSE-effect relationship in pharmacology, *ENZYME inhibitors, *LIGNANS, *MEDICINAL plants, *SPECTRUM analysis, *PHYTOCHEMICALS, *PLANT extracts, *DESCRIPTIVE statistics, *IN vitro studies, *PHARMACODYNAMICS
Abstract

Two new lignans were isolated from Saururus chinensis , along with eight known compounds. Their structures were elucidated on the basis of spectroscopic and physico-chemical analyses. All the isolates were evaluated for in vitro inhibitory activity against DGAT1 and DGAT2. Among them, compounds 2 , 3 , 5 and 7 were found to exhibit selective inhibitory activity on DGAT1 with IC 50 values ranging from 44.3 ± 1.5 to 87.5 ± 1.3 μM. [ABSTRACT FROM AUTHOR]

Published
2015
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3. COMPARISON OF TWO BIOELECTRICAL IMPEDANCE ANALYSIS DEVICES WITH DUAL ENERGY X-RAY ABSORPTIOMETRY AND MAGNETIC RESONANCE IMAGING IN THE ESTIMATION OF BODY COMPOSITION.

Author

Ji-Guang Wang, Yi Zhang, Han-e Chen, Yan Li, Xiao-Guang Cheng, Li Xu, Zhe Guo, Xing-Shan Zhao, Tetsuya Sato, Qi-Yun Cao, Ke-Min Chen, and Biao Li

Subjects
*BODY composition, *ADIPOSE tissues, *ANTHROPOMETRY, *HUMAN body composition, *COMPARATIVE studies, *CONFIDENCE intervals, *BIOELECTRIC impedance, *MAGNETIC resonance imaging, *RESEARCH funding, *STATISTICS, *T-test (Statistics), *X-ray densitometry in medicine, *PRODUCT design, *STATISTICAL power analysis, *EVALUATION research, *BODY mass index, *INTER-observer reliability, *WAIST-hip ratio, *LEAN body mass, *MEDICAL equipment reliability, *WAIST circumference, *DESCRIPTIVE statistics, *EVALUATION
Abstract

The article discusses the comparison of a four-limb bioelectrical impedance analysis (BIA) system and a two-limb foot-to-foot device with dual energy X-ray absorptiometry (DXA) and magnetic resonance imaging (MRI) methods for measuring body composition. Topics include the study's experimental design, the global prevalence of obesity, and the benefits of BIA in estimating body composition, including body fat percentage (BF), skeletal muscle mass percentage (SMM), and visceral fat level (VF).

Published
2013
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