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[Objective] The present paper aimed to reveal the landscape pattern evolution and driving factors of karst rocky desertification area, and provide a reference for optimizing the land landscape pattern, rocky desertification control and regional sustainable development in the demonstration area. [Method] Taking the typical Karst Plateau Bijie Salaxi demonstration area as the research object, the remote sensing images of three key time periods were selected, including ETM in 2005, 2010 and OLI in 2015. 3 S technology and landscape index analysis method were employed to study landscape pattern and the driving factors. [Result] The main landscape of the study area was cultivated land, followed by shrub forest. The changes of landscape transfer were mainly manifested in the transformation from cultivated land to forest, grassland and construction land, which accounted for 73. 31 % and 24. 75 % of the cultivated land transfer respectively in 2010; By 2015, they accounted for 79. 80 % and 19. 99 % respectively. At the landscape type level, the fragmentation degree of cultivated land, forestland and shrub land was increasing, and the fragmentation degree of grassland and construction land increased first and then decreased. Except for the unused land, the landscape patch shape tended to be complicated. In the overall level of the landscape, the landscape of demonstration area had developed in the direction of fragmentation, complexity, discretization and homogenization in the last 10 years. [Conclusion] The implementation of rocky desertification control project, urbanization construction and land abandonment were the main factors leading to the change of landscape pattern. [ABSTRACT FROM AUTHOR]