Search

Your search keyword '"Moazzam, Parisa"' showing total 1 results
Start Over Author "Moazzam, Parisa" Topic detection limit
1 results on '"Moazzam, Parisa"'

1. Ultrasensitive detection of programmed death-ligand 1 (PD-L1) in whole blood using dispersible electrodes.

Author

Moazzam, Parisa, Myekhlai, Munkhshur, Alinezhad, Ali, Alshawawreh, Fida'a A., Bakthavathsalam, Padmavathy, Gonçales, Vinicius R, Tilley, Richard D., and Gooding, J. Justin

Subjects
*PROGRAMMED death-ligand 1, *PROGRAMMED cell death 1 receptors, *ELECTRODES, *MAGNETIC nanoparticles, *DETECTION limit
Abstract

The direct quantification of programmed death-ligand 1 (PD-L1) as a biomarker for cancer diagnosis, prognosis and treatment efficacy is an unmet clinical need. Herein, we demonstrate the first report of rapid, ultrasensitive and selective electrochemical detection of PD-L1 directly in undiluted whole blood using modified gold-coated magnetic nanoparticles as "dispersible electrodes" with an ultralow detection limit of 15 attomolar and a response time of only 15 minutes. [ABSTRACT FROM AUTHOR]

Published
2021
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results