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[Display omitted] • A highly selective Hg2+ sensor QPE was developed based on quinolimide. • QPE had high sensitivity, low LOD and LOQ, wide pH range, and rapid response. • QPE -loaded test strips were fabricated for the visual detection of Hg2+. • QPE had been used for tracing Hg2+ in real water and soil samples and living cells. Herein, a novel fluorescent sensor QPE based on quinolimide was developed, which displayed the highly selective response to Hg2+ through the turn-on signal in aqueous media. The corresponding recognition mechanism of QPE for Hg2+ was investigated by the titration experiments, Job's plots, HRMS, and DFT calculations analysis. QPE could detect Hg2+ in a broad pH range (pH = 4–9) with the LOD of 20 nM and the LOQ of 66 nM. Meanwhile, QPE -loaded test strips were demonstrated in the visual detection of Hg2+. Importantly, QPE exhibited the reliable capability to track Hg2+ in real water and soil samples and yeast cells, indicating that QPE could be used as a prospective tool for monitoring Hg2+ in wide fields. [ABSTRACT FROM AUTHOR]

A novel sensor T2 was synthesized through the introduction of N,N -di (pyridin-2-ylmethyl)ethane-1,2-diamine into the quinolimide fluorophore. T2 could detect Cd2+ and Zn2+ via fluorescence enhanced signals, and Cd2+ was distinguished from Zn2+ through the visible color change and the addition of S2−. The T2 -Cd2+ complex exhibited the exceptional selectivity to S2− through the restored fluorescence. Moreover, the combinational logic gate with OR and INHIBIT functions was constructed by using the controlled fluorescence "off-on" states of T2. The recoveries of Cd2+ and Zn2+ in water samples with T2 were in range of 95.6%–106.5%. And T2 was used for the visualization of Cd2+, Zn2+, and S2− in yeast cells. [Display omitted] • The quinolimide-based sensor T2 was developed for sensing Cd2+, Zn2+, and S2−. • T2 could distinguish Cd2+ from Zn2+ through the visible color change and the addition of S2−. • The T2-Cd2+ complex exhibited the exceptional selectivity to S2−. • The combinational logic gate with OR and INHIBIT functions was constructed. • T2 was applied to detect Cd2+, Zn2+, and S2− in water samples as well as in yeast cells. [ABSTRACT FROM AUTHOR]

[Display omitted] A new quinolimide derivative MSH was designed and developed as a highly sensitive Zn2+ fluorescent turn-on sensor in neutral aqueous media. After binding Zn2+ with a 2:1 stoichiometry, the excellent fluorescence enhancement (Φ Zn(II) = 0.555) of MSH was observed, along with the low LOD of 8 nM, wide pH usage range (pH = 4–12), and fast response time of less than 15 s. The combinational logic gate and the memory device were constructed to take advantage of the emission of MSH controlled by Zn2+ and EDTA. Additionally, Zn2+ in actual water samples was detected with the satisfactory recovery rates between 96.6 % and 104 %. And MSH was successfully fabricated into paper strips and used as an imaging tool in yeast cells for tracking Zn2+ levels. [ABSTRACT FROM AUTHOR]

[Display omitted] • A simple FA sensor H2 was developed based on quinolimide for the first time. • H2 had highly selective and sensitive to FA by the pseudo -first-order reaction. • H2 -loaded test strips were fabricated for the visual detection of FA. • H2 had been successfully applied to detect FA in living cells. A simple fluorescent sensor H2 containing quinolimide as a fluorophore and hydrazine as a reaction site was designed and synthesized for the detection of formaldehyde (FA). H2 had the high selectivity and sensitivity to FA through the pseudo -first-order reaction (k = 0.048 min−1), exhibiting the significantly enhanced fluorescence signal. The quantitative determination range of H2 for FA was 0–180 μM, and the LOD of FA is 1.7 μM. Moreover, H2 -loaded test strips were demonstrated in the visualization of sensing FA. And H2 was successfully applied for imaging FA in living cells. [ABSTRACT FROM AUTHOR]

• A quinolimide-based reversible sensor QPC for Cu2+ and S2− was developed. • QPC and its Cu2+ complex had the high specificity to detect Cu2+ and S2−. • QPC possessed high quantum yield, short response time, and low cytotoxicity. • The INHIBIT logic gate was simulated by the addition of Cu2+ and S2−. • QPC had been applied to detect Cu2+ and S2− in water samples and living cells. A quinolimide-based reversible fluorescent sensor QPC with carboxamidoquinoline as the receptor was prepared for the relay recognition of Cu2+ and S2−. QPC displayed the high selectivity and anti-interference ability to Cu2+ through the 1:1 binding mode. Subsequently, the selectively sensing S2− with the QPC Cu2+ complex gave a remarkable recovery of the emission. The LODs of QPC and its Cu2+ complex for Cu2+ and S2− were calculated to be 47.8 nM and 0.178 µM, respectively. Moreover, QPC and its Cu2+ complex had the satisfactory recoveries 93.5–105.8% for Cu2+ and 97.7–104.0% for S2− in water samples, and exhibited low cytotoxicity, which enabled them to image Cu2+ and S2− in yeast cells. [Display omitted] [ABSTRACT FROM AUTHOR]

A novel quinolimide derivative (BNAL), bearing the amide-DPA receptor at position 9 of the heterocyclic ring, was synthesized for sequential detection of Cd2+ and S2−. BNAL could discriminate Cd2+ from Zn2+, showing the turn-on response upon interaction with Cd2+. After adding S2−, the fluorescence of the BNAL -Cd2+ solution was reverted through the displacement strategy. The limits of detection (LODs) of BNAL for Cd2+ and the BNAL -Cd2+ complex for S2− were found to be 17.9 nM and 1.51 μM, respectively. Finally, cell imaging experiments showed BNAL could be successfully employed for sequentially imaging Cd2+ and S2− via the off-on-off behavior in yeast cells. [Display omitted] [ABSTRACT FROM AUTHOR]