113 results on '"Kahn, C. Ronald"'
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2. Cell-Replacement Therapy for Diabetes: Generating Functional Insulin-Producing Tissue from Adult Human Liver Cells
3. Distinct Pathways of Insulin-Regulated versus Diabetes-Regulated Gene Expression: An in vivo Analysis in MIRKO Mice
4. Central Role of Suppressors of Cytokine Signaling Proteins in Hepatic Steatosis, Insulin Resistance, and the Metabolic Syndrome in the Mouse
5. Coordinated Reduction of Genes of Oxidative Metabolism in Humans with Insulin Resistance and Diabetes: Potential Role of PGC1 and NRF1
6. Insulin Resistance Is a Poor Predictor of Type 2 Diabetes in Individuals with No Family History of Disease
7. Coordinated Patterns of Gene Expression for Substrate and Energy Metabolism in Skeletal Muscle of Diabetic Mice
8. Characterization of the Met326Ile Variant of Phosphatidylinositol 3-Kinase p85α
9. Unbalanced Expression of the Different Subunits of Elongation Factor 1 in Diabetic Skeletal Muscle
10. Insulin resistance in brain alters dopamine turnover and causes behavioral disorders
11. Loss of insulin signaling in astrocytes exacerbates Alzheimer-like phenotypes in a 5xFAD mouse model.
12. Cold but not sympathomimetics activates human brown adipose tissue in vivo
13. Sucrose nonfermenting AMPK-related kinase (SNARK) mediates contraction-stimulated glucose transport in mouse skeletal muscle
14. Mutations at the BLK Locus Linked to Maturity Onset Diabetes of the Young and ß-Cell Dysfunction
15. Impaired Sodium Excretion and Increased Blood Pressure in Mice with Targeted Deletion of Renal Epithelial Insulin Receptor
16. Overexpression of the Dual-Specificity Phosphatase MKP-4/DUSP-9 Protects against Stress-Induced Insulin Resistance
17. Dissection of the Insulin Signaling Pathway via Quantitative Phosphoproteomics
18. Ectopic Brown Adipose Tissue in Muscle Provides a Mechanism for Differences in Risk of Metabolic Syndrome in Mice
19. Phosphoinositide 3-Kinase Regulatory Subunit p85α Suppresses Insulin Action via Positive Regulation of PTEN
20. Evidence for a Role of Developmental Genes in the Origin of Obesity and Body Fat Distribution
21. Analysis of Gene Expression in Pathophysiological States: Balancing False Discovery and False Negative Rates
22. Decreased Muscle Glucose Transport/Phosphorylation is an Early Defect in the Pathogenesis of Non-Insulin-Dependent Diabetes Mellitus
23. Direct Demonstration that Receptor Crosslinking or Aggregation is Important in Insulin Action
24. Insulin Receptor Substrate 1 Mediates Insulin and Insulin-Like Growth Factor I-Stimulated Maturation of Xenopus Oocytes
25. Optimizing Transmembrane Domain Helicity Accelerates Insulin Receptor Internalization and Lateral Mobility
26. Direct Method for Detection and Characterization of Cell Surface Receptors for Insulin by means of 125I-Labeled Autoantibodies against the Insulin Receptor
27. The Insulin Receptor with Phenylalanine Replacing Tyrosine-1146 Provides Evidence for Separate Signals Regulating Cellular Metabolism and Growth
28. Sharing of Biological Effect and Receptors between Guinea Pig Insulin and Platelet-Derived Growth Factor
29. Radioimmunoassay of the Insulin Receptor: A New Probe of Receptor Structure and Function
30. Transcriptomic Regulation of Muscle Mitochondria and Calcium Signaling by Insulin/IGF-1 Receptors Depends on FoxO Transcription Factors.
31. HNFs: Linking the Liver and Pancreatic Islets in Diabetes
32. Antibodies That Impair Insulin Receptor Binding in an Unusual Diabetic Syndrome with Severe Insulin Resistance
33. Mice Carrying a Dominant-Negative Human PI3K Mutation Are Protected From Obesity and Hepatic Steatosis but Not Diabetes.
34. Diabetes primes neutrophils to undergo NETosis, which impairs wound healing.
35. Genetic Insulin Resistance Is a Potent Regulator of Gene Expression and Proliferation in Human iPS Cells.
36. Insulin and insulin-like growth factor 1 receptors are required for normal expression of imprinted genes.
37. Adipose tissue mitochondrial dysfunction triggers a lipodystrophic syndrome with insulin resistance, hepatosteatosis, and cardiovascular complications.
38. Complex mechanisms linking neurocognitive dysfunction to insulin resistance and other metabolic dysfunction
39. Absence of Diabetes and Pancreatic Exocrine Dysfunction in a Transgenic Model of Carboxyl-Ester Lipase-MODY (Maturity-Onset Diabetes of the Young).
40. Reduction of the Cholesterol Sensor SCAP in the Brains of Mice Causes Impaired Synaptic Transmission and Altered Cognitive Function.
41. Lessons on Conditional Gene Targeting in Mouse Adipose Tissue.
42. Insulin regulates liver metabolism in vivo in the absence of hepatic Akt and Foxo1.
43. Insulin Augmentation of Glucose-Stimulated Insulin Secretion Is Impaired in Insulin-Resistant Humans.
44. Dietary Leucine - An Environmental Modifier of Insulin Resistance Acting on Multiple Levels of Metabolism.
45. Mesodermal developmental gene Tbx15 impairs adipocyte differentiation and mitochondrial respiration.
46. Class IA Phosphatidylinositol 3-Kinase in Pancreatic β Cells Controls Insulin Secretion by Multiple Mechanisms.
47. Diabetes and Insulin in Regulation of Brain Cholesterol Metabolism.
48. A Systems Biology Approach Identifies Inflammatory Abnormalities Between Mouse Strains Prior to Development of Metabolic Disease.
49. Sex and Depot Differences in Adipocyte Insulin Sensitivity and Glucose Metabolism.
50. Beneficial Effects of Subcutaneous Fat Transplantation on Metabolism.
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