1. [The incretory function of the pancreas in patients with pulmonary tuberculosis and diabetes mellitus].
- Author
-
Egorova IL
- Subjects
- Adult, Diabetes Mellitus, Type 1 complications, Diabetes Mellitus, Type 2 complications, Female, Humans, Male, Middle Aged, Tuberculosis, Pulmonary complications, Diabetes Mellitus, Type 1 physiopathology, Diabetes Mellitus, Type 2 physiopathology, Pancreas metabolism, Tuberculosis, Pulmonary physiopathology
- Abstract
Serum C-peptide levels were studied in 88 patients with pulmonary tuberculosis concurrent with diabetes mellitus. The pancreatic incretory function in combined pathology was found to be related both to the type and severity of diabetes mellitus and the severity of tuberculosis. Specific and medicamental intoxication negatively affects residual insulin secretion and the body's insulin-sensitivity. High functional capacity of B-cells of the pancreas and insulin resistance in noninsulin dependent diabetes, on the one hand, and rapid depletion of the insular apparatus in serious chronic tuberculosis, on the other, made it possible to recommend combined hypoglycemic therapy with insulin and oral sugar-lowering drugs to patients with a prolonged severe course of each of the diseases (pulmonary tuberculosis and Type II diabetes) in their combination.
- Published
- 1991