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Objective: This study aimed to evaluate the relationship between working hours and glycemic control., Methods: Study was performed among Korean participants who underwent at least two health screening examinations between 2012 and 2018. The study included 2169 participants who were older than 40 years and undergoing treatment for diabetes at baseline. A hemoglobin A1c level >9% at the follow-up visit was defined as poor glycemic control. The weekly working hours were divided into three groups for analysis., Results: Compared with participants with 45-54 weekly working hours, multivariate-adjusted hazard ratios (95% confidence intervals) for incident poor glycemic control among participants with ≥55 and 35-44 working hours were 1.40 (1.01-1.96) and 1.51 (1.09-2.09), respectively., Conclusions: Standard working hours and long working hours were independent risk factors for poor diabetes control in patients with diabetes., Competing Interests: Conflict of interest: None declared., (Copyright © 2022 American College of Occupational and Environmental Medicine.)

Long working hours have negative effects on the health of workers. Several studies have reported the association between long working hours and both diabetes and prediabetes. Therefore, we aimed to examine the temporal relationship between long working hours and glucose intolerance. Our cohort study collected data from 25,803 healthy male participants at baseline. To evaluate the risk of incident glucose intolerance, we estimated the hazard ratios (HRs) and 95% confidence intervals (CIs) using the Cox proportional hazards regression analyses. During 77,605.0 person-years of follow-up, 6741 participants developed glucose intolerance. Multivariable-adjusted HRs (95% CI) for weekly working 41-52 and >52 h compared with working 35-40 h, were 1.28 (1.17-1.40) and 2.80 (2.54-3.09), respectively. In the dose-response analyses, long working hours had a nearly linear relationship with the development of glucose intolerance across most working hours per week. The association between long working hours and incident glucose intolerance was stronger in the younger-age subgroups than in the older-age subgroups ( p for interaction <0.001). Our large-scale cohort study demonstrated that long working hours were associated with incident glucose intolerance, with a dose-response relationship.