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The risk of kidney damage doubles during pregnancy. Acute kidney injury in pregnancy (P-AKI) is a high risk obstetrical disease that threatens the lives of mothers and their children. Despite the decline in the incidence of P-AKI in the past three decades, China still has a high incidence and mortality rate. P-AKI is a serious complication of pregnancy. It has clinical features of rapid onset, rapid progress and serious illness, often accompanied by respiratory, cardiovascular and digestive symptoms. P-AKI related diseases such as pre -eclampsia, acute fatty liver in pregnancy, HELLP syndrome and thrombotic microangiopathy have similar clinical manifestations and are prone to diagnosis difficulties. This article analyzes the pathophysiological changes, the incidence and causes of different countries, the diagnostic criteria, the related diseases of PAKI and the preventive and therapeutic measures, further analyzes the dialysis for P-AKI. It aims to improve the prevention and treatment of P-AKI, reduce the incidence, mortality and disability, and improve maternal and child outcomes. [ABSTRACT FROM AUTHOR]

According to the standard method and procedures for the development of evidence-based medicine guidelines, a multi-disciplinary guideline development working group was established. Through the process of guideline registration, guideline plan writing, analysis of relevant guidelines, clinical problem screening and determination, clinical evidence retrieval and evaluation, forming of recommendation, etc. and after three rounds of discussions by the consensus expert group, a new evidence-based guideline for diagnosis and treatment of senile osteoporosis in China (2018) was developed. The grading of recommendations assessment, development and evaluation (GRADE) system was used to rate the quality of evidence and the strength of recommendations. Recommendations were derived from body of evidence, and at the same time considered the balance of benefits and harms as well as values and preferences of Chinese patients. The guideline development working group developed 15 recommendations for the diagnosis and treatment of senile osteoporosis. The guideline covered the screening for senile osteoporosis, risk assessment, diagnosis, basic treatment, multiple anti-osteoporosis drugs, therapeutic effect monitoring and evaluation of senile osteoporosis. This guideline aims to provide scientific evidence for clinicians and patients in China. [ABSTRACT FROM AUTHOR]

Objective · To investigate the clinicopathologic characteristics and prognosis of adult rhabdomyosarcoma (RMS). Methods · The clinical and pathological data, immunohistochemical test results of 9 RMS were analyzed retrospectively. Results · The information of 6 males and 3 females were collected in this research, whose average age was (46.89±20.09) years old. The tumors had a wide range distribution. The subtypes of histology included 6 cases of embryonal RMS, 1 case of alveolar RMS, 1 case of spindle cell RMS and 1 case of pleomorphic RMS. Immunohistochemically study showed that 6 cases were myogenin positive, 4 cases were MyoD1 positive and 8 cases were desmin positive. During the follow-up period of the 7 cases, only 2 patients survived free of tumors, 2 patients presented with tumor recurrence and metastasis after the operations, and 3 patients died of tumor. Conclusion · In this study, embryonal RMS is the most common type, and immunohistochemistry test is helpful to diagnosis of RMS. [ABSTRACT FROM AUTHOR]

Objective To compare the diagnostic reliability of intertochanteric fracture AO and Evans-Jensen classifications in X ray film and three-dimensional CT reconstruction images and explore advantage of the three-dimensional CT. Methods A retrospective study was performed to evaluate 54 intertochanteric fractures．Thress orthopaedic surgeonswere asked to make assessment of fracture classifications using X ray film and the three-dimensional CT images. Agreement test was performed to evaluate interobserver and intraobserver reliability for fracture classification. Results When X ray film was used, interobserver reliability mean kappa value between three surgeons for AO and Evans-Jensen classifications were 0.597 (0.547-0.653) and 0.571 (0.539-0.600), medium consistency. While using three-dimensional CT to AO classification lower kappa value was 0.411 (0.366-0.455), medium consistency, Evans - Jensen classification kappa value was 0.704 (0.671-0.737), highly consistency. Each surgeon respectively through the X ray film and three-dimensional CT the AO and Evans-Jensen classification mean kappa value were 0.464 (0.406-0.579), medium consistency and 0.191 (0.160-0.233), weak consistency. Conclusion Both classifications based on X ray film showed moderate consistency , using three-dimensional CT does not improve the consistency of AO classification. And the three-dimensional CT does not apply to Evans-Jensen classification. [ABSTRACT FROM AUTHOR]

Primary liver adenosquamous carcinoma is a rare kind of liver malignant tumor with very poor prognosis. Clinical data of 5 cases were analyzed retrospectively, four male and one female, whose average age was 60.2 years (50-67 years) old. Adenosquamous carcinoma contains both adenocarcinoma and squamous carcinoma histologically, and squamous carcinoma cells are dominant (>80%). Four cases underwent surgical resection and one received liver transplantation. The postoperative follow-up period ranged from 6 to 35 months and the mean survival time of these cases was about 15 months. Three patients died during the follow-up period. The survival rates 1 and 2 years after operation were 60% and 20%, respectively. [ABSTRACT FROM AUTHOR]