Abdukahil, Sheryl, Hssain, Ali, Tamlihat, Younes, Alidjnou, Kazali, de Brito, Carlos, Assie, Jean, Rincon, Diego, Humaid, Felwa, Bosse, Hans, Calvache, Jose, Carrier, François, Cavalli, Giulio, Cheng, Matthew, Cho, Hwa, Cho, Sung, Cidade, Jose, Herreros, Jose, Citarella, Barbara, Colombo, Sebastiano, Corpuz, Arianne, D’orleans, Charles, de Oliveira França, Rafael, Dewayanti, Santi, Diaz, Juan, Douglas, James, Mangoni, Emanuele, Dyrhol-Riise, Anne, Vidal, José, Sanharawi, Mohammed, Everding, Anna, Fatoni, Arie, Devouge, Eglantine, Florio, Letizia, Fonseca, Claudio, Freire, Marcela, Ribeiro, Ana, Curto, Elena, Morlaes, Louis, Grandin, Edward, Grieco, Domenico, Lordemann, Anja, Ho, Antonia, Holter, Jan, Horcajada, Juan, Dominguez, Carmen, Sotomayor, Ruth, García, Ruth, Kandamby, Darshana, Johal, Simreen, Kildal, Anders, Bekken, Gry, Vasconcelos, Malte, Vecham, Pavan, Lantang, Eka, Santos, Marta, Lee, Su, Bassi, Gianluigi, Lim, Wei, Lucet, Jean, Müller, Karl, Sanchez, Juan, Maier, Lars, Sant, Ceila, Eid, Charbel, Martelli, Celina, Rego, Caroline, Marwali, Eva, Jimenez, Juan, Maldonado, Hugo, Tutillo, Diego, Perrot, Clara, Myrodia, Dimitra, Ng, Pauline, Ng, Wing, Choileain, Orna, Oinam, Budha, Oliveira, Ana, Orozco-Chamorro, Claudia, Panda, Prasan, Reyes, Luis, Rios, Ana, Nuñez, Maria, Abreu, Julia, Holten, Aleksander, Choez, Xavier, Shum, Hoi, Mohammed, Nassima, Silva, Maria, Sin, Wai, Song, Myung, Uva, Maria, Svistunov, Magdalena, Thuy, Duong, Vijayaraghavan, Bharath, Santos-Olmo, Rosario, Trieu, Huynh, Villanueva, Joy, Abdukahil, Sheryl Ann, Abe, Ryuzo, Abel, Laurent, Absil, Lara, Acker, Andrew, Adachi, Shingo, Adam, Elisabeth, Adrião, Diana, Ainscough, Kate, Hssain, Ali Ait, Tamlihat, Younes Ait, Akimoto, Takako, Al-Dabbous, Tala, Al-Fares, Abdulrahman, Al Qasim, Eman, Alalqam, Razi, Alex, Beatrice, Alexandre, Kévin, Alfoudri, Huda, Alidjnou, Kazali Enagnon, Aliudin, Jeffrey, Allavena, Clotilde, Allou, Nathalie, Alves, João, Alves, Rita, Amaral, Maria, Ammerlaan, Heidi, Ampaw, Phoebe, Andini, Roberto, Andrejak, Claire, Angheben, Andrea, Angoulvant, François, Ansart, Séverine, Antonelli, Massimo, de Brito, Carlos Alexandre Antunes, Arabi, Yaseen, Aragao, Irene, Arcadipane, Antonio, Arenz, Lukas, Arlet, Jean-Benoît, Arnold-Day, Christel, Arora, Lovkesh, Artaud-Macari, Elise, Asensio, Angel, Assie, Jean Baptiste, Atique, Anika, Auchabie, Johann, Aumaitre, Hugues, Azemar, Laurène, Azoulay, Cécile, Bach, Benjamin, Bachelet, Delphine, Baillie, J. Kenneth, Bak, Erica, Bakakos, Agamemnon, Banisadr, Firouzé, Barbalho, Renata, Barclay, Wendy, Barnikel, Michaela, Barrelet, Audrey, Barrigoto, Cleide, Basmaci, Romain, Rincon, Diego Fernando Bautista, Bedossa, Alexandra, Behilill, Sylvie, Beljantsev, Aleksandr, Bellemare, David, Beltrame, Anna, Beluze, Marine, Benech, Nicolas, Benkerrou, Dehbia, Bennett, Suzanne, Bento, Luís, Berdal, Jan-Erik, Bergeaud, Delphine, Bertolino, Lorenzo, Bessis, Simon, Bevilcaqua, Sybille, Bhavsar, Krishna, Humaid, Felwa Bin, Bissuel, François, Biston, Patrick, Bitker, Laurent, Blanco-Schweizer, Pablo, Blot, Mathieu, Boccia, Filomena, Bogaert, Debby, Bompart, François, Booth, Gareth, Borges, Diogo, Borie, Raphaël, Bos, Jeannet, Bosse, Hans Martin, Botelho-Nevers, Elisabeth, Bouadma, Lila, Bouchaud, Olivier, Bouchez, Sabelline, Bouhmani, Dounia, Bouhour, Damien, Bouiller, Kévin, Bouillet, Laurence, Bouisse, Camille, Boureau, Anne-Sophie, Bouscambert, Maude, Bouziotis, Jason, Boxma, Bianca, Boyer-Besseyre, Marielle, Boylan, Maria, Braga, Cynthia, Brandenburger, Timo, Brazzi, Luca, Breen, Dorothy, Breen, Patrick, Brickell, Kathy, Brozzi, Nicolas, Buchtele, Nina, Buesaquillo, Christian, Bugaeva, Polina, Buisson, Marielle, Burhan, Erlina, Bustos, Ingrid, Butnaru, Denis, Cárcel, Sheila, Cabie, André, Cabral, Susana, Caceres, Eder, Callahan, Mia, Calligy, Kate, Calvache, Jose Andres, Camões, João, Campana, Valentine, Campbell, Paul, Canepa, Cecilia, Cantero, Mireia, Caraux-Paz, Pauline, Cardoso, Filipa, Cardoso, Filipe, Cardoso, Sofia, Carelli, Simone, Carlier, Nicolas, Carney, Gayle, Carpenter, Chloe, Carret, Marie-Christine, Carrier, François Martin, Carson, Gail, Casanova, Maire-Laure, Cascão, Mariana, Casimiro, José, Cassandra, Bailey, Castañeda, Silvia, Castanheira, Nidyanara, Castor-Alexandre, Guylaine, Castrillón, Henry, Castro, Ivo, Catarino, Ana, Catherine, François-Xavier, Cavalin, Roberta, Cavalli, Giulio Giovanni, Cavayas, Alexandros, Ceccato, Adrian, Cervantes-Gonzalez, Minerva, Chair, Anissa, Chakveatze, Catherine, Chan, Adrienne, Chand, Meera, Chas, Julie, Chassin, Camille, Chen, Anjellica, Chen, Yih-Sharng, Cheng, Matthew Pellan, Cheret, Antoine, Chiarabini, Thibault, Chica, Julian, Chirouze, Catherine, Chiumello, Davide, Cho, Hwa Jin, Cho, Sung Min, Cholley, Bernard, Cidade, Jose Pedro, Herreros, Jose Miguel Cisneros, Citarella, Barbara Wanjiru, Ciullo, Anna, Clarke, Jennifer, Clohisey, Sara, Codan, Cassidy, Cody, Caitriona, Coelho, Alexandra, Colin, Gwenhaël, Collins, Michael, Colombo, Sebastiano Maria, Combs, Pamela, Connelly, J., Connor, Marie, Conrad, Anne, Contreras, Sofía, Cooke, Graham, Copland, Mary, Cordel, Hugues, Corley, Amanda, Cormican, Sarah, Cornelis, Sabine, Corpuz, Arianne Joy, Corvaisier, Grégory, Couffignal, Camille, Couffin-Cadiergues, Sandrine, Courtois, Roxane, D’orleans, Charles Crepy, Croonen, Sabine, Crowl, Gloria, Crump, Jonathan, Cruz, Claudina, Csete, Marc, Cucino, Alberto, Cullen, Caroline, Cummings, Matthew, Curley, Gerard, Curlier, Elodie, Custodio, Paula, D’aragon, Frédérick, da Silva Filipe, Ana, da Silveira, Charlene, D’ortenzio, Eric, Dabaliz, Al-Awwab, Dagens, Andrew, Dalton, Heidi, Dalton, Jo, Daneman, Nick, Dankwa, Emmanuelle, Dantas, Jorge, de Castro, Nathalie, de Mendoza, Diego, de Oliveira França, Rafael Freitas, de Rosa, Rosanna, de Silva, Thushan, de Vries, Peter, Dean, David, Debray, Marie-Pierre, Dechert, William, Deconninck, Lauren, Decours, Romain, Delacroix, Isabelle, Delavigne, Karen, Deligiannis, Ionna, Dell’amore, Andrea, Delobel, Pierre, Demonchy, Elisa, Denis, Emmanuelle, Deplanque, Dominique, Depuydt, Pieter, Desai, Mehul, Descamps, Diane, Desvallée, Mathilde, Dewayanti, Santi Rahayu, Diallo, Alpha, Diamantis, Sylvain, Dias, André, Diaz, Juan Jose Diaz, Diaz, Rodrigo, Didier, Kévin, Diehl, Jean-Luc, Dieperink, Wim, Dimet, Jérôme, Dinot, Vincent, Diouf, Alphonsine, Dishon, Yael, Djossou, Félix, Docherty, Annemarie, Dong, Andy, Donnelly, Christl, Donnelly, Maria, Donohue, Chloe, 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Stephanie-Susanne, Stienstra, Ymkje, Stiksrud, Birgitte, Streinu-Cercel, Adrian, Streinu-Cercel, Anca, Strudwick, Samantha, Stuart, Ami, Stuart, David, Sultana, Asfia, Summers, Charlotte, Svistunov, Magdalena Surovcová Andrey A., Syrigos, Konstantinos, Sztajnbok, Jaques, Szuldrzynski, Konstanty, Téoulé, François, Tabrizi, Shirin, Tagherset, Lysa, Talarek, Ewa, Taleb, Sara, Talsma, Jelmer, Le Van, Tan, Tanaka, Hiroyuki, Tanaka, Taku, Taniguchi, Hayato, Tardivon, Coralie, Tattevin, Pierre, Taufik, M. Azhari, Tedder, Richard, Teixeira, João, Tellier, Marie-Capucine, Terpstra, Pleun, Terrier, Olivier, Terzi, Nicolas, Tessier-Grenier, Hubert, Thibault, V., Thiberville, Simon-Djamel, Thill, Benoît, Thompson, A., Thompson, Shaun, Thomson, David, Thomson, Emma, Thuy, Duong Bich, Thwaites, Ryan, Timashev, Peter, Timsit, Jean-François, Vijayaraghavan, Bharath Kumar Tirupakuzhi, Toki, Maria, Tonby, Kristian, Santos-Olmo, Rosario Maria Torres, Torres, Antoni, Torres, Margarida, Trioux, Théo, Trieu, Huynh Trung, Tromeur, Cécile, Trontzas, Ioannis, Troost, Jonathan, Trouillon, Tiffany, Tual, Christelle, Tubiana, Sarah, Tuite, Helen, Turtle, Lance, Twardowski, Pawel, Uchiyama, Makoto, Ullrich, Roman, Uribe, Alberto, Usman, Asad, Val-Flores, Luís, van de Velde, Stijn, van den Berge, Marcel, van Der Feltz, Machteld, van Der Vekens, Nicky, van Der Voort, Peter, van Der Werf, Sylvie, van Dyk, Marlice, van Gulik, Laura, van Hattem, Jarne, van Lelyveld, Steven, van Netten, Carolien, Vanel, Noémie, Vanoverschelde, Henk, Vauchy, Charline, Veislinger, Aurélie, Velazco, Jorge, Ventura, Sara, Verbon, Annelies, Vieira, César, Villanueva, Joy Ann, Villar, Judit, Villeneuve, Pierre-Marc, Villoldo, Andrea, van Vinh Chau, Nguyen, Visseaux, Benoit, Visser, Hannah, Vuorinen, Aapeli, Vuotto, Fanny, Wang, Chih-Hsien, Wei, Jia, Weil, Katharina, Wesselius, Sanne, Wham, Murray, Whelan, Bryan, White, Nicole, Wiedemann, Aurélie, Wille, Keith, Wils, Evert-Jan, Xynogalas, Ioannis, Suen, Jacky, Yacoub, Sophie, Yamazaki, Masaki, Yazdanpanah, Yazdan, Yelnik, Cécile, Yerkovich, Stephanie, Yokoyama, Toshiki, Yonis, Hodane, Young, Paul, Yuliarto, Saptadi, Zabbe, Marion, Zacharowski, Kai, Zahran, Maram, Zambon, Maria, Zanella, Alberto, Zawadka, Konrad, Zayyad, Hiba, Zoufaly, Alexander, Zucman, David, Abdukahil, S. A., Abe, R., Abel, L., Absil, L., Acker, A., Adachi, S., Adam, E., Adriao, D., Ainscough, K., Hssain, A. A., Tamlihat, Y. A., Akimoto, T., Al-Dabbous, T., Al-Fares, A., Al Qasim, E., Alalqam, R., Alex, B., Alexandre, K., Alfoudri, H., Alidjnou, K. E., Aliudin, J., Allavena, C., Allou, N., Alves, J., Alves, R., Amaral, M., Ammerlaan, H., Ampaw, P., Andini, R., Andrejak, C., Angheben, A., Angoulvant, F., Ansart, S., Antonelli, M., De Brito, C. A. A., Arabi, Y., Aragao, I., Arcadipane, A., Arenz, L., Arlet, J. -B., Arnold-Day, C., Arora, L., Artaud-Macari, E., Asensio, A., Assie, J. B., Atique, A., Auchabie, J., Aumaitre, H., Azemar, L., Azoulay, C., Bach, B., Bachelet, D., Baillie, J. K., Bak, E., Bakakos, A., Banisadr, F., Barbalho, R., Barclay, W. S., Barnikel, M., Barrelet, A., Barrigoto, C., Basmaci, R., Rincon, D. F. B., Bedossa, A., Behilill, S., Beljantsev, A., Bellemare, D., Beltrame, A., Beluze, M., Benech, N., Benkerrou, D., Bennett, S., Bento, L. I., Berdal, J. -E., Bergeaud, D., Bertolino, L., Bessis, S., Bevilcaqua, S., Bhavsar, K., Humaid, F. B., Bissuel, F., Biston, P., Bitker, L., Blanco-Schweizer, P., Blot, M., Boccia, F., Bogaert, D., Bompart, F., Booth, G., Borges, D., Borie, R., Bos, J., Bosse, H. M., Botelho-Nevers, E., Bouadma, L., Bouchaud, O., Bouchez, S., Bouhmani, D., Bouhour, D., Bouiller, K., Bouillet, L., Bouisse, C., Boureau, A. -S., Bouscambert, M., Bouziotis, J., Boxma, B., Boyer-Besseyre, M., Boylan, M., Braga, C., Brandenburger, T., Brazzi, L., Breen, D., Breen, P., Brickell, K., Brozzi, N., Buchtele, N., Buesaquillo, C., Bugaeva, P., Buisson, M., Burhan, E., Bustos, I. G., Butnaru, D., Carcel, S., Cabie, A., Cabral, S., Caceres, E., Callahan, M., Calligy, K., Calvache, J. A., Camoes, J., Campana, V., Campbell, P., Canepa, C., Cantero, M., Caraux-Paz, P., Cardoso, F., Cardoso, S., Carelli, S., Carlier, N., Carney, G., Carpenter, C., Carret, M. -C., Carrier, F. 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Y., Yacoub, S., Yamazaki, M., Yazdanpanah, Y., Yelnik, C., Yerkovich, S., Yokoyama, T., Yonis, H., Young, P., Yuliarto, S., Zabbe, M., Zacharowski, K., Zahran, M., Zambon, M., Zanella, A., Zawadka, K., Zayyad, H., Zoufaly, A., Zucman, D., Apollo - University of Cambridge Repository, Human genetics of infectious diseases: Complex predisposition (Equipe Inserm U1163), Imagine - Institut des maladies génétiques (IHU) (Imagine - U1163), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), Department of Mathematics and Statistics, Wichita State University, Service d'Anésthésie Réanimation [CHU Clermont-Ferrand], CHU Estaing [Clermont-Ferrand], CHU Clermont-Ferrand-CHU Clermont-Ferrand, Laboratoire Chrono-environnement (UMR 6249) (LCE), Centre National de la Recherche Scientifique (CNRS)-Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC), Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon), Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Cardiovascular and Renal Clinical Trialists [Vandoeuvre-les-Nancy] (INI-CRCT), Institut Lorrain du Coeur et des Vaisseaux Louis Mathieu [Nancy], French-Clinical Research Infrastructure Network - F-CRIN [Paris] (Cardiovascular & Renal Clinical Trialists - CRCT ), Centre d'investigation clinique plurithématique Pierre Drouin [Nancy] (CIC-P), Centre d'investigation clinique [Nancy] (CIC), Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lorraine (UL)-Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lorraine (UL), Défaillance Cardiovasculaire Aiguë et Chronique (DCAC), Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lorraine (UL), Institut Pasteur [Paris] (IP), Génétique Moléculaire des Virus à ARN - Molecular Genetics of RNA Viruses (GMV-ARN (UMR_3569 / U-Pasteur_2)), Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), This work was supported by the Department for International Development and Wellcome Trust [215091/Z/18/Z], the Bill and Melinda Gates Foundation [OPP1209135]. Country-specific support was provided by the Canadian Institutes of Health Research Coronavirus Rapid Research Funding Opportunity [OV2170359], the Health Research Board Ireland [CTN Award 2014-012], National Institute for Health Research (NIHR) [award CO-CIN-01], the Medical Research Council (MRC) [grant MC_PC_19059], the NIHR Health Protection Research Unit (HPRU) in Emerging and Zoonotic Infections at University of Liverpool in partnership with Public Health England (PHE), in collaboration with Liverpool School of Tropical Medicine and the University of Oxford [award 200907], NIHR HPRU in Respiratory Infections at Imperial College London with PHE [award 200927], Liverpool Experimental Cancer Medicine Centre [grant reference C18616/A25153], NIHR Biomedical Research Centre at Imperial College London [IS-BRC-1215-20013], EU Platform for European Preparedness Against (Re-)emerging Epidemics (PREPARE) [FP7 project 602525], National Institutes of Health (NIH) [UL1TR002240], and NIHR Clinical Research Network infrastructure support. We acknowledge the generous support of all ISARIC Partners who have contributed data and expertise to this analysis, with or without dedicated funding. The views expressed are those of the authors and not necessarily those of the funders or institutions listed above., European Project: 602525,EC:FP7:HEALTH,FP7-HEALTH-2013-INNOVATION-1,PREPARE(2014), Infectious diseases, Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Paris (UP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Paris (UP), Laboratoire Chrono-environnement - CNRS - UBFC (UMR 6249) (LCE), Université de Lorraine (UL)-Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lorraine (UL)-Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy)-Institut National de la Santé et de la Recherche Médicale (INSERM), Critical care, Anesthesiology, Peri-operative and Emergency medicine (CAPE), Medical Research Council (MRC), National Institute for Health Research, UKRI MRC COVID-19 Rapid Response Call, UK Research and Innovation, and BOZEC, Erwan