1. Colorectal cancer staging: comparison of whole-body PET/CT and PET/MR.
- Author
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Catalano, Onofrio, Coutinho, Artur, Sahani, Dushyant, Vangel, Mark, Gee, Michael, Hahn, Peter, Witzel, Thomas, Soricelli, Andrea, Salvatore, Marco, Catana, Ciprian, Mahmood, Umar, Rosen, Bruce, and Gervais, Debra
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COLON cancer , *POSITRON emission tomography , *COMPUTED tomography , *DIAGNOSTIC imaging , *NUCLEAR medicine - Abstract
Purpose: Correct staging is imperative for colorectal cancer (CRC) since it influences both prognosis and management. Several imaging methods are used for this purpose, with variable performance. Positron emission tomography-magnetic resonance (PET/MR) is an innovative imaging technique recently employed for clinical application. The present study was undertaken to compare the staging accuracy of whole-body positron emission tomography-computed tomography (PET/CT) with whole-body PET/MR in patients with both newly diagnosed and treated colorectal cancer. Methods: Twenty-six patients, who underwent same day whole-body (WB) PET/CT and WB-PET/MR, were evaluated. PET/CT and PET/MR studies were interpreted by consensus by a radiologist and a nuclear medicine physician. Correlations with prior imaging and follow-up studies were used as the reference standard. Correct staging was compared between methods using McNemar's Chi square test. Results: The two methods were in agreement and correct for 18/26 (69%) patients, and in agreement and incorrect for one patient (3.8%). PET/MR and PET/CT stages for the remaining 7/26 patients (27%) were discordant, with PET/MR staging being correct in all seven cases. PET/MR significantly outperformed PET/CT overall for accurate staging ( P = 0.02). Conclusion: PET/MR outperformed PET/CT in CRC staging. PET/MR might allow accurate local and distant staging of CRC patients during both at the time of diagnosis and during follow-up. [ABSTRACT FROM AUTHOR]
- Published
- 2017
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