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Aims: To assess the efficacy of a β-galactomannan oligosaccharide (ß-GMOS) for the control of Salmonella infection in fattening pigs., Methods and Results: Three different doses (0.5, 3 and 2 kg ß-GMOS per ton of feed) were used during the entire period of growing in three similar and independent field trials carried out in a small fattening unit (≈ 100 pigs). Treatment was randomly assigned to half of the pens. Individual serum samples (20-25 per group) were collected at different times during the fattening period and a similar number of faecal samples during the fattening period and at slaughter. In addition, mesenteric lymph nodes were collected at slaughter. Herdcheck(®) Swine Salmonella ELISA was used for serological analyses, the ISO 6579:2002/Amd 1 : 2007 for bacteriology and the PFGE for molecular characterization of Salmonella strains. The addition of ≥ 2 kg t(-1) of ß-GMOS to the pig diet during the entire fattening period was associated with a reduction in Salmonella prevalence, shedding and seroconversion., Conclusions: Feed supplementation with ß-GMOS may be a useful complementary tool for the control of salmonellosis in fattening pigs., Significance and Impact of the Study: ß-GMOS may be a complementary way of reducing Salmonella shedding and infection in fattening pigs., (© 2014 The Society for Applied Microbiology.)

The effects of mannan oligosaccharide (MOS) as a dietary supplement on growth performance, carcass traits and mortality in meat guinea pigs were compared to a commonly used antimicrobial growth promoter (AGP, Zn-Bacitracin). The four experimental treatments were as follow: Control group (no additives); MOS 1 (1.5 g kg−1); MOS 2 (2 g kg−1) and AGP (0.1 g kg−1). The guinea pigs were housed in 40 floor pens containing a deep litter of woodchips (n = 100 animals in each trial; 10 animals per pen). Guinea pigs were all weaned on day 28 and their body weight was measured weekly. All animals were slaughtered at the end of fattening period (day 77) and carcass traits were evaluated. Significant differences against the control group were observed for traits studied (P < 0.05). Between MOS groups and AGP no significant differences were observed. In conclusion, the use of MOS could be a suitable replacement for antibiotic growth promoter to raise guinea pigs. [ABSTRACT FROM AUTHOR]

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A 28-day experiment was carried out to evaluate the effect of dietary prebiotic mannan oligosaccharide (MOS) on the growth, survival, intestinal morphometry and nonspecific immune response of the Siamese fighting fish (Betta splendens Regan, 1910) larvae. The MOS supplementation levels evaluated was: 0, 2, 4 and 6 g kg-1. Into 16 plastic aquaria (3 L) 240 larvae (4.21 ± 0.26 mm) were distributed at a density of 5 larvae L-1. All larvae received live food for seven days, followed by a period of eight days of co-feeding (live food + inert diet) and, finally, 13 days of inert diet. At the end of feeding-trial, there were no significant differences between growth, survival, intestinal morphometry and alkaline phosphatase activity of larvae fed the control or MOS supplemented diets. However, the lysozyme activity in larvae fed 2 g MOS kg-1 was significantly higher compared to other treatments. For fish farming, the most beneficial effects of prebiotics reside in its ability to enhance the immune system of fish. In this context, this study revealed that, although the MOS supplementation has no effect on growth, survival and intestinal morphometry, 2 g MOS kg-1 supplementation for B. splendens larvae hint at a possible immunomodulatory effect, as evidenced by the increase in lysozyme activity. [ABSTRACT FROM AUTHOR]

Abstract: A 84-day study was conducted to determine the effect of combination of whole millet feeding and mannan oligosaccharides (MOS) supplementation on growth performance, serum biochemistry and relative organ weights of growing guinea fowl. 192 One-day-old, male guinea fowls were randomly allocated to four treatment groups of 48 guinea fowl split over six replicates of eight birds. Dietary treatments were arranged in a 2×2 factorial arrangements of two diet forms (whole millet diets (WMD) and completely ground diets (CGD)) supplemented with and without 1g/kg MOS. WMD contained similar feed ingredients as CGD except that certain quantity of millet grains (150g/kg for 1–29 days and 450g/kg for 29–84 days birds) were progressively removed and fed whole for WMD-fed group. Birds fed WMD had reduced (P<0.05) feed intake and improved (P<0.05) feed to gain ratio when compared to group fed CGD. Supplementation of MOS in diets for growing guinea fowl (29–84 days) notwithstanding the feed form resulted in increased (P<0.05) total serum protein, reduced (P<0.01) serum uric acid and cholesterol concentration. Birds fed WMD had higher (P<0.05) gizzard and thymus weights while dietary supplementation of MOS showed reduced (P<0.05) liver weights and increased (P<0.05) spleen weight. It was concluded that whole millet feeding when combined with MOS supplementation in growing guinea fowls showed improved growth performance, gizzard development, serum chemistry and positive influence on organ weights. [Copyright &y& Elsevier]

The effect of the dietary supplementation of mannan oligosaccharides (MOS) on hydrogen ion concentration of the digestive tract and microbial populations of the ceca of the Japanese quail (Coturnix japonica) was investigated in this experimentation. Two hundred twenty-five 1-day old Japanese quail divided into 3 groups, with 3 subgroups each, were fed a basal diet that served as control, or a basal diet containing 1 g MOS/kg or 2 g MOS/kg. On days 21 and 42, hydrogen ion concentrations of the quail crop, proventriculus, gizzard, duodenum, jejunum, ileum, large intestine, and ceca were measured in situ. Furthermore, on the same days, the total aerobic bacteria, lactic acid bacteria, Enterobacteriaceae, and coliform counts of the cecal content were recorded. The results of the experimentation showed that the dietary supplementation of MOS in the feed of growing quail did not significantly affect the hydrogen ion concentration in various parts of the digestive tract, the bacterial counts in the ceca and the mortality of growing healthy Japanese quail reared in unstressed conditions. [ABSTRACT FROM AUTHOR]

Presents abstracts of several studies on feed additives. "Growth Performance of Male Broiler Chicks Fed Diets Supplemented With Two Levels of Versazyme to 26 Days of Age," by N. H. Odetallah, M. H. Fosnaught and J. C. H. Shih; "Effect of Mannan Oligosaccharides Supplementation to Laying Hen Diets," by M. I. Gracia, P. Cachaldora, L. Tucker, F. Baucells and P. Medel; "Efficacy of Purified β-mannanase Isolated From Hemicell® in Broiler Chickens With Coccidiosis and Necrotic Enteritis," by H.-Y. Hsiao, D. M. Anderson, M. E. Jackson, F. L. Jin and G. F. Mathis.

Presents abstracts of several studies on feed additives. "Growth Performance of Male Broiler Chicks Fed Diets Supplemented With Two Levels of Versazyme to 26 Days of Age," by N. H. Odetallah, M. H. Fosnaught and J. C. H. Shih; "Effect of Mannan Oligosaccharides Supplementation to Laying Hen Diets," by M. I. Gracia, P. Cachaldora, L. Tucker, F. Baucells and P. Medel; "Efficacy of Purified β-mannanase Isolated From Hemicell® in Broiler Chickens With Coccidiosis and Necrotic Enteritis," by H.-Y. Hsiao, D. M. Anderson, M. E. Jackson, F. L. Jin and G. F. Mathis.

Presents abstracts of several studies on feed additives. "Growth Performance of Male Broiler Chicks Fed Diets Supplemented With Two Levels of Versazyme to 26 Days of Age," by N. H. Odetallah, M. H. Fosnaught and J. C. H. Shih; "Effect of Mannan Oligosaccharides Supplementation to Laying Hen Diets," by M. I. Gracia, P. Cachaldora, L. Tucker, F. Baucells and P. Medel; "Efficacy of Purified β-mannanase Isolated From Hemicell® in Broiler Chickens With Coccidiosis and Necrotic Enteritis," by H.-Y. Hsiao, D. M. Anderson, M. E. Jackson, F. L. Jin and G. F. Mathis.