1. Short communication: Diffusion tensor anisotropy in the cingulate in borderline and schizotypal personality disorder.
- Author
-
Goldstein KE, Haznedar MM, Alloy LB, Drabick DAG, McClure MM, New AS, Chu KW, Vaccaro D, Tang CY, Meyerson D, and Hazlett EA
- Subjects
- Adolescent, Adult, Anisotropy, Female, Humans, Male, Middle Aged, Schizotypal Personality Disorder psychology, Young Adult, Diffusion Tensor Imaging methods, Gyrus Cinguli diagnostic imaging, Schizotypal Personality Disorder diagnostic imaging, White Matter diagnostic imaging
- Abstract
Despite considerable phenomentological differences between borderline personality disorder (BPD) and schizotypal personality disorder (SPD), research increasingly provides evidence that some BPD symptoms overlap with SPD symptoms (e.g., disturbed cognitions). We examined the cingulate, a brain region implicated in the pathophysiology of both disorders, to determine similarities/differences between the groups, and similarities/differences from healthy controls (HC's). 3T structural and diffusion tensor magnetic resonance imaging scans were acquired in BPD (n = 27), SPD (n = 32), HC's (n = 34). Results revealed that BPD patients exhibited significantly lower FA in posterior cingulate white matter compared to HC's (p = 0.04), but SPD patients did not., (Published by Elsevier B.V.)
- Published
- 2019
- Full Text
- View/download PDF