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Your search keyword '"Alessia Lanno"' showing total 2 results
Start Over Author "Alessia Lanno" Topic dihydroorotate dehydrogenase
2 results on '"Alessia Lanno"'

1. Targeting Acute Myelogenous Leukemia Using Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on the 2-Hydroxypyrazolo[1,5-a]pyridine Scaffold: SAR of the Aryloxyaryl Moiety

Author

Stefano Sainas, Marta Giorgis, Paola Circosta, Giulio Poli, Marta Alberti, Alice Passoni, Valentina Gaidano, Agnese C. Pippione, Nicoletta Vitale, Davide Bonanni, Barbara Rolando, Alessandro Cignetti, Cristina Ramondetti, Alessia Lanno, Davide M. Ferraris, Barbara Canepa, Barbara Buccinnà, Marco Piccinini, Menico Rizzi, Giuseppe Saglio, Salam Al-Karadaghi, Donatella Boschi, Riccardo Miggiano, Tiziano Tuccinardi, and Marco L. Lolli

Subjects
Myeloid, Oxidoreductases Acting on CH-CH Group Donors, Leukemia, Pyridines, Dihydroorotate Dehydrogenase, Dipyridamole, Acute, Antiviral Agents, Mice, Structure-Activity Relationship, Animals, Enzyme Inhibitors, Humans, Leukemia, Myeloid, Acute, Drug Discovery, Molecular Medicine
Published
2022
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2. Targeting Acute Myelogenous Leukemia Using Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on the 2-Hydroxypyrazolo[1,5

Author

Stefano, Sainas, Marta, Giorgis, Paola, Circosta, Giulio, Poli, Marta, Alberti, Alice, Passoni, Valentina, Gaidano, Agnese C, Pippione, Nicoletta, Vitale, Davide, Bonanni, Barbara, Rolando, Alessandro, Cignetti, Cristina, Ramondetti, Alessia, Lanno, Davide M, Ferraris, Barbara, Canepa, Barbara, Buccinnà, Marco, Piccinini, Menico, Rizzi, Giuseppe, Saglio, Salam, Al-Karadaghi, Donatella, Boschi, Riccardo, Miggiano, Tiziano, Tuccinardi, and Marco L, Lolli

Subjects
Leukemia, Myeloid, Acute, Mice, Oxidoreductases Acting on CH-CH Group Donors, Structure-Activity Relationship, Pyridines, Dihydroorotate Dehydrogenase, Animals, Humans, Dipyridamole, Enzyme Inhibitors, Antiviral Agents
Abstract

In recent years, human dihydroorotate dehydrogenase inhibitors have been associated with acute myelogenous leukemia as well as studied as potent host targeting antivirals. Starting from MEDS433 (IC

Published
2022

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