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Your search keyword '"Wehrberger, Kurt"' showing total 2 results
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2 results on '"Wehrberger, Kurt"'

1. Nuclear DNA from two early Neandertals reveals 80,000 years of genetic continuity in Europe.

Author

Peyrégne S, Slon V, Mafessoni F, de Filippo C, Hajdinjak M, Nagel S, Nickel B, Essel E, Le Cabec A, Wehrberger K, Conard NJ, Kind CJ, Posth C, Krause J, Abrams G, Bonjean D, Di Modica K, Toussaint M, Kelso J, Meyer M, Pääbo S, and Prüfer K

Subjects
Animals, Cell Lineage genetics, Europe, Evolution, Molecular, Fossils, Genome genetics, Germany, Mitochondria genetics, Cell Nucleus genetics, DNA genetics, Neanderthals genetics
Abstract

Little is known about the population history of Neandertals over the hundreds of thousands of years of their existence. We retrieved nuclear genomic sequences from two Neandertals, one from Hohlenstein-Stadel Cave in Germany and the other from Scladina Cave in Belgium, who lived around 120,000 years ago. Despite the deeply divergent mitochondrial lineage present in the former individual, both Neandertals are genetically closer to later Neandertals from Europe than to a roughly contemporaneous individual from Siberia. That the Hohlenstein-Stadel and Scladina individuals lived around the time of their most recent common ancestor with later Neandertals suggests that all later Neandertals trace at least part of their ancestry back to these early European Neandertals.

Published
2019
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2. The genetic history of Ice Age Europe

Author

Alexander Peltzer, Dorothée G. Drucker, Annamaria Ronchitelli, Stephan Schiffels, Maria Teschler-Nicola, Swapan Mallick, Svante Pääbo, Michael P. Richards, Daniel Fernandes, Martin Petr, Manuel R. González Morales, Marco Peresani, Jiří Svoboda, V. S. Slavinsky, Janet Kelso, David Reich, Isabelle Crevecoeur, Pontus Skoglund, E. Vacca, Francesco Mallegni, Donato Coppola, Oana Teodora Moldovan, Cosimo Posth, Nadin Rohland, Kurt Wehrberger, Anatoly P. Derevianko, Birgit Nickel, A. A. Tsybankov, Viviane Slon, Nicholas J. Conard, Stefano Ricci, Christine Neugebauer-Maresch, Corinne Thevenet, Qiaomei Fu, Lawrence Guy Straus, Vyacheslav Moiseyev, Frédérique Valentin, Johannes Krause, Iain Mathieson, Silviu Constantin, Mateja Hajdinjak, Sahra Talamo, Bernard Gély, Renata Grifoni Cremonesi, Dan Grigorescu, David Caramelli, Mark Lipson, Matthias Meyer, Damien Flas, Stefano Benazzi, Alissa Mittnik, Nick Patterson, Iosif Lazaridis, Martina Lari, Hervé Bocherens, Wolfgang Haak, Katerina Harvati, Patrick Semal, Christophe Cupillard, Hélène Rougier, Ron Pinhasi, Marcello A. Mannino, Anja Furtwängler, Nikolai I. Drozdov, Department of Genetics [Boston], Harvard Medical School [Boston] (HMS), Max Planck Institute for the Science of Human History (MPI-SHH), Max-Planck-Gesellschaft, Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology [Leipzig], Max-Planck-Gesellschaft-Max-Planck-Gesellschaft, Harvard School of Public Health, School of Archaeology [Dublin], University College Dublin [Dublin] (UCD), Eberhard Karls Universität Tübingen = Eberhard Karls University of Tuebingen, Université libre de Bruxelles (ULB), Department of Evolutianory Genetics, Max-Planck-Institut, Sackler Faculty of Medicine, Tel Aviv University (TAU), Department of Human Evolution [Leipzig], Nuffield Department of Medicine, Service régional de l'Archéologie Rhône-Alpes, Ministère de la Culture et de la Communication (MCC), Laboratory of Excellence for Financial Regulation (LABEX ReFi), Université Paris-Sud - Paris 11 (UP11), Institutul de Speologie ‘Emil Racoviţă', Str. Frumoasă 31, Alma Mater Studiorum Università di Bologna [Bologna] (UNIBO), Università degli Studi di Ferrara = University of Ferrara (UniFE), Università degli Studi di Firenze = University of Florence (UniFI), Department of Information Engineering [Firenze], U.R. Ecologia Preistorica, Dipartimento di Scienze Ambientali ', Archéologies et Sciences de l'Antiquité (ArScAn), Université Paris 1 Panthéon-Sorbonne (UP1)-Université Paris 8 Vincennes-Saint-Denis (UP8)-Université Paris Nanterre (UPN)-Ministère de la Culture et de la Communication (MCC)-Institut national de recherches archéologiques préventives (Inrap)-Centre National de la Recherche Scientifique (CNRS), Museum Ulm, De la Préhistoire à l'Actuel : Culture, Environnement et Anthropologie (PACEA), Université de Bordeaux (UB)-Centre National de la Recherche Scientifique (CNRS), Service Anthropologie et Préhistoire [Bruxelles], Institut Royal des Sciences Naturelles de Belgique (IRSNB), Laboratoire Chrono-environnement (UMR 6249) (LCE), Centre National de la Recherche Scientifique (CNRS)-Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC), Institut für Ur- und Frühgeschichte und Archäologie des Mittelalters, University of Tübingen, Faculty of Science [Brno] (SCI / MUNI), Masaryk University [Brno] (MUNI), Department of Physics, University of Sussex, Department of Animal Biology and Genetics, School of Archaeology, Broad Institute of MIT and Harvard (BROAD INSTITUTE), Harvard Medical School [Boston] (HMS)-Massachusetts Institute of Technology (MIT)-Massachusetts General Hospital [Boston], Centre International de Recherche Archéologique sur la Polynésie (CIRAP), Université de la Polynésie Française (UPF), Tel Aviv University [Tel Aviv], Università degli Studi di Ferrara (UniFE), Università degli Studi di Firenze = University of Florence [Firenze] (UNIFI), Université Paris 1 Panthéon-Sorbonne (UP1)-Université Paris Nanterre (UPN)-Ministère de la Culture et de la Communication (MCC)-Centre National de la Recherche Scientifique (CNRS), Laboratoire Chrono-environnement - CNRS - UBFC (UMR 6249) (LCE), Max Planck Institute for Evolutionary Anthropology, Eberhard Karls Universität Tübingen, Max-Planck-Institut für evolutionäre Anthropologie (MPI-EVA), University College of London [London] (UCL), Laboratoire Chrono-environnement - CNRS - UFC (UMR 6249) (LCE), Department of Archaeogenetics [Jena] (DAG), Laboratoire Chrono-environnement ( LCE ), Université Bourgogne Franche-Comté ( UBFC ) -Centre National de la Recherche Scientifique ( CNRS ) -Université de Franche-Comté ( UFC ), University of Bologna, Dipartimento di Scienze Fisiche, della Terra e dell'Ambiente., Università degli Studi di Siena = University of Siena (UNISI), Laboratoire d'Anthropologie et de Préhistoire, Institut royal des Sciences naturelles de Belgique (IRSNB), Travaux et recherches archéologiques sur les cultures, les espaces et les sociétés (TRACES), Ministère de la Culture et de la Communication (MCC)-École des hautes études en sciences sociales (EHESS)-Université Toulouse - Jean Jaurès (UT2J)-Centre National de la Recherche Scientifique (CNRS), Institut Royal des Sciences naturelles de Belgique, Univ Tubingen, Senckenberg Ctr Human Evolut & Palaeoecol, Palaeoanthropol, Tubingen, Germany, Laboratorio di Antropologia, Università degli Studi di Firenze = University of Florence [Firenze], Qiaomei, Fu, Posth, Cosimo, Hajdinjak, Mateja, Petr, Martin, Mallick, Swapan, Fernandes, Daniel, Furtwängler, Anja, Haak, Wolfgang, Meyer, Matthia, Mittnik, Alissa, Nickel, Birgit, Peltzer, Alexander, Rohland, Nadin, Slon, Viviane, Talamo, Sahra, Lazaridis, Iosif, Lipson, Mark, Mathieson, Iain, Schiffels, Stephan, Skoglund, Pontu, Derevianko, Anatoly P., Drozdov, Nikolai, Slavinsky, Vyacheslav, Tsybankov, Alexander, Cremonesi, Renata Grifoni, Mallegni, Francesco, Gély, Bernard, Vacca, Eligio, Morales, Manuel R. González, Straus, Lawrence G., Neugebauer Maresch, Christine, Teschler Nicola, Maria, Constantin, Silviu, Moldovan, Oana Teodora, Benazzi, Stefano, Peresani, Marco, Coppola, Donato, Lari, Martina, Ricci, Stefano, Ronchitelli, Annamaria, Valentin, Frédérique, Thevenet, Corinne, Wehrberger, Kurt, Grigorescu, Dan, Rougier, Hélène, Crevecoeur, Isabelle, Flas, Damien, Semal, Patrick, Mannino, Marcello A., Cupillard, Christophe, Bocherens, Hervé, Conard, Nicholas J., Harvati, Katerina, Moiseyev, Vyacheslav, Drucker, Dorothée G., Svoboda, Jiří, Richards, Michael P., Caramelli, David, Pinhasi, Ron, Kelso, Janet, Patterson, Nick, Krause, Johanne, Pääbo, Svante, and Reich, David

Subjects
0301 basic medicine, Male, Neanderthal, Time Factors, [SDV]Life Sciences [q-bio], Population Dynamics, [SHS.ANTHRO-BIO]Humanities and Social Sciences/Biological anthropology, Neanderthal genome project, migration, Ancient Modern Humans, [SHS]Humanities and Social Sciences, 0302 clinical medicine, Ice Cover, History, Ancient, Phylogeny, ComputingMilieux_MISCELLANEOUS, Modern Humans, Neanderthals, Genetics, education.field_of_study, Multidisciplinary, Ancient DNA, Human migration, Biological Evolution, Founder Effect, Pleistocene, Europe, Ethnology, Female, Ancient DNA, Ancient Modern Humans, Neanderthals, Human, Animals, DNA, European Continental Ancestry Group, Genetics, Population, Human Migration, Humans, Middle East, Selection, Genetic, Sequence Analysis, DNA, Medicine (all), Archaeogenetics, Time Factor, [SHS.ARCHEO]Humanities and Social Sciences/Archaeology and Prehistory, Modern Humans, Genetics, Pleistocene, Europe, migration, culture, Europe glaciaire, Population, Socio-culturale, Biology, Article, White People, Prehistory, 03 medical and health sciences, [SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN], biology.animal, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, education, Population Dynamic, Homo sapiens, Animal, business.industry, culture, 030104 developmental biology, [ SHS.ARCHEO ] Humanities and Social Sciences/Archaeology and Prehistory, business, génome humain, 030217 neurology & neurosurgery, Founder effect
Abstract

Modern humans arrived in Europe ∼45,000 years ago, but little is known about their genetic composition before the start of farming ∼8,500 years ago. Here we analyse genome-wide data from 51 Eurasians from ∼45,000-7,000 years ago. Over this time, the proportion of Neanderthal DNA decreased from 3-6% to around 2%, consistent with natural selection against Neanderthal variants in modern humans. Whereas there is no evidence of the earliest modern humans in Europe contributing to the genetic composition of present-day Europeans, all individuals between ∼37,000 and ∼14,000 years ago descended from a single founder population which forms part of the ancestry of present-day Europeans. An ∼35,000-year-old individual from northwest Europe represents an early branch of this founder population which was then displaced across a broad region, before reappearing in southwest Europe at the height of the last Ice Age ∼19,000 years ago. During the major warming period after ∼14,000 years ago, a genetic component related to present-day Near Easterners became widespread in Europe. These results document how population turnover and migration have been recurring themes of European prehistory.

Published
2016
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