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Your search keyword '"Latif, F."' showing total 31 results
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31 results on '"Latif, F."'

3. A new polymorphic probe on chromosome 3p: lambda LIB27-98" (D3S1096).

Author

Latif F, Glenn GM, Geil L, Rayford W, Delisio J, Zbar B, and Lerman MI

Subjects
Deoxyribonuclease EcoRI metabolism, Humans, White People, von Hippel-Lindau Disease genetics, Chromosomes, Human, Pair 3, DNA Probes genetics, Polymorphism, Genetic genetics
Published
1991

4. A new polymorphic probe on chromosome 3p: lambda LIB27-77 (D3S603).

Author

Latif F, Glenn GM, Geil L, Rayford W, Yao M, Delisio J, Zbar B, and Lerman MI

Subjects
Deoxyribonuclease HindIII metabolism, Humans, White People, von Hippel-Lindau Disease genetics, Chromosomes, Human, Pair 3, DNA Probes genetics, Polymorphism, Genetic genetics
Published
1991

5. A new polymorphic probe on chromosome 3p: lambda LIB45-86 (D3S633).

Author

Latif F, Glenn GM, Geil L, Rayford W, Delisio J, Zbar B, and Lerman MI

Subjects
Deoxyribonucleases, Type II Site-Specific metabolism, Humans, White People, von Hippel-Lindau Disease genetics, Chromosomes, Human, Pair 3, DNA Probes genetics, Polymorphism, Genetic genetics
Published
1991

7. A new polymorphic probe on chromosome 3p: lambda LIB13-67 (D3S591).

Author

Latif F, Glenn GM, Geil L, Ryford W, Delisio J, Zbar B, and Lerman MI

Subjects
Deoxyribonuclease HpaII, Deoxyribonucleases, Type II Site-Specific metabolism, Humans, White People, von Hippel-Lindau Disease genetics, Chromosomes, Human, Pair 3, DNA Probes genetics, Polymorphism, Genetic genetics
Published
1991

10. A new polymorphic probe on chromosome 3p:lambda LIB35-53(D3S731).

Author

Latif F, Glenn GM, Rayford W, Geil L, Yao M, Delisio J, Hampsch K, Orcutt ML, Zbar B, and Lerman MI

Subjects
Chromosome Mapping, Deoxyribonucleases, Type II Site-Specific metabolism, Humans, Chromosomes, Human, Pair 3, DNA Probes, Polymorphism, Restriction Fragment Length
Published
1991

11. A new polymorphic probe on chromosome 3p:lambda LIB46-95(D3S620).

Author

Latif F, Glenn GM, Rayford W, Geil L, Delisio J, Hampsch K, Orcutt ML, Zbar B, and Lerman MI

Subjects
Chromosome Mapping, Deoxyribonucleases, Type II Site-Specific metabolism, Humans, Chromosomes, Human, Pair 3, DNA Probes, Polymorphism, Restriction Fragment Length
Published
1991

12. A new polymorphic probe on chromosome 3p:lambda LIB30-62'(D3S606).

Author

Latif F, Glenn GM, Rayford W, Geil L, Yao M, Delisio J, Hampsch K, Orcutt ML, Zbar B, and Lerman MI

Subjects
Chromosome Mapping, Deoxyribonuclease EcoRI metabolism, Humans, Chromosomes, Human, Pair 3, DNA Probes, Polymorphism, Restriction Fragment Length
Published
1991

13. A new polymorphic probe on chromosome 3p:lambda LIB29-48(D3S624).

Author

Latif F, Glenn GM, Rayford W, Geil L, Delisio J, Hampsch K, Orcutt ML, Zbar B, and Lerman MI

Subjects
Chromosome Mapping, Deoxyribonuclease HpaII, Deoxyribonucleases, Type II Site-Specific metabolism, Humans, Chromosomes, Human, Pair 3, DNA Probes, Polymorphism, Restriction Fragment Length
Published
1991

14. A new polymorphic probe on chromosome 3p:lambda LIB46-35'(D3S636).

Author

Latif F, Glenn GM, Rayford W, Geil L, Delisio J, Hampsch K, Orcutt ML, Zbar B, and Lerman MI

Subjects
Chromosome Mapping, Deoxyribonucleases, Type II Site-Specific metabolism, Humans, Bacterial Proteins, Chromosomes, Human, Pair 3, DNA Probes, Polymorphism, Restriction Fragment Length
Published
1991

15. A new polymorphic probe on chromosome 3p:lambda LIB41-10(D3S618).

Author

Latif F, Glenn GM, Rayford W, Wei M, Geil L, Delisio J, Hampsch K, Orcutt ML, Zbar B, and Lerman MI

Subjects
Chromosome Mapping, Deoxyribonuclease HindIII metabolism, Humans, Chromosomes, Human, Pair 3, DNA Probes, Polymorphism, Restriction Fragment Length
Published
1991

16. A new polymorphic probe on chromosome 3p:lambda LIB28-62(D3S736).

Author

Delisio J, Latif F, Glenn GM, Geil L, Yao M, Hampsch K, Orcutt ML, Zbar B, and Lerman MI

Subjects
Chromosome Mapping, Deoxyribonuclease HpaII, Deoxyribonucleases, Type II Site-Specific metabolism, Humans, Chromosomes, Human, Pair 3, DNA Probes, Polymorphism, Restriction Fragment Length
Published
1991

19. A new polymorphic probe on chromosome 3p: lambda LIB15-44 (D3S596).

Author

Latif F, Glenn GM, Brauch H, Delisio J, Hampsch K, Orcutt ML, Zbar B, and Lerman MI

Subjects
Chromosome Mapping, DNA-Directed DNA Polymerase, Heterozygote, Humans, Taq Polymerase, Chromosomes, Human, Pair 3, DNA Probes, Polymorphism, Genetic
Published
1991

20. A new polymorphic probe on chromosome 3p: lambda LIB19-63' (D3S601).

Author

Delisio J, Latif F, Glenn GM, Yao M, Brauch H, Hampsch K, Orcutt ML, Zbar B, and Lerman MI

Subjects
Chromosome Mapping, DNA-Directed DNA Polymerase, Heterozygote, Humans, Taq Polymerase, Chromosomes, Human, Pair 3, DNA Probes, Polymorphism, Genetic
Published
1991

21. A new polymorphic probe on chromosome 3p: lambda LIB03-23 (D3S573).

Author

Latif F, Glenn GM, Brauch H, Delisio J, Hampsch K, Orcutt ML, Zbar B, and Lerman MI

Subjects
Chromosome Mapping, Deoxyribonuclease HpaII, Deoxyribonucleases, Type II Site-Specific, Heterozygote, Humans, Chromosomes, Human, Pair 3, DNA Probes, Polymorphism, Genetic
Published
1991

24. A new polymorphic probe on chromosome 3p: lambda LIB09-75' (D3S584).

Author

Delisio J, Latif F, Glenn GM, Yao M, Brauch H, Hampsch K, Orcutt ML, Zbar B, and Lerman MI

Subjects
Chromosome Mapping, DNA-Directed DNA Polymerase, Heterozygote, Humans, Taq Polymerase, Chromosomes, Human, Pair 3, DNA Probes, Polymorphism, Genetic
Published
1991

26. A new polymorphic probe on chromosome 3p:λLIB37 – 96′ (D3S1192)

Author

Latif, F., Glenn, G.M., Geil, L., Delisio, J., Zbar, B., and Lerman, M.I.

Subjects
Polymorphism, Genetic, von Hippel-Lindau Disease, Humans, Chromosomes, Human, Pair 3, DNA Probes, Deoxyribonucleases, Type II Site-Specific, Deoxyribonuclease HpaII, White People
Published
1991

27. A new polymorphic probe on chromosome 3p:λLIB30-62′(D3S606)

Author

Latif, F., Glenn, G.M., Rayford, W., Geil, L., Yao, M., Delisio, J., Hampsch, K., Orcutt, M.L., Zbar, B., and Lerman, M.I.

Subjects
Chromosome Mapping, Humans, Chromosomes, Human, Pair 3, DNA Probes, Polymorphism, Restriction Fragment Length, Deoxyribonuclease EcoRI
Published
1991

28. A new polymorphic probe on chromosome 3p:λLIB46-35′(D3S636)

Author

Latif, F., Glenn, G.M., Rayford, W., Geil, L., Delisio, J., Hampsch, K., Orcutt, M.L., Zbar, B., and Lerman, M.I.

Subjects
Bacterial Proteins, Chromosome Mapping, Humans, Chromosomes, Human, Pair 3, DNA Probes, Deoxyribonucleases, Type II Site-Specific, Polymorphism, Restriction Fragment Length
Published
1991

29. Molecular analysis of genetic changes in the origin and development of renal cell carcinoma

Author

Anglard P, Tory K, Hiltrud Brauch, Gh, Weiss, Latif F, Mj, Merino, Mi, Lerman, Zbar B, and Wm, Linehan

Subjects
Adult, Chromosome Aberrations, Male, Chromosomes, Human, Pair 13, Chromosomes, Human, Pair 11, Chromosome Mapping, DNA, Middle Aged, Kidney Neoplasms, Humans, Female, Genes, Tumor Suppressor, Chromosomes, Human, Pair 3, Chromosome Deletion, DNA Probes, Carcinoma, Renal Cell, Polymorphism, Restriction Fragment Length, Aged, Chromosomes, Human, Pair 17, Densitometry
Abstract

Renal cell carcinoma has been characterized by an abnormality on the short arm of chromosome 3 which suggests the presence of a tumor suppressor gene at this location. In order to more precisely define the location of the renal cell carcinoma gene and to differentiate molecular changes occurring in early stages of renal neoplasia versus those occurring later in malignant progression, DNA from normal and tumor tissue from 60 patients with various stages of renal cell carcinoma was analyzed for loss of alleles at different chromosomal loci. In tumor tissue from 51 of 58 evaluable patients (88%) there was loss of heterozygosity at one or more of 10 loci tested on chromosome 3 independently of tumor stage. Analysis of the genotypes identified the distal portion of 3p bounded by D3S2 and D3S22 (3p21-26) as the region of the disease gene. In tumor tissue from patients with advanced renal cell carcinoma, we found loss of heterozygosity on chromosome 11p in 5 of 21 (24%), on chromosome 13 in 3 of 9 (33%), and on chromosome 17 in 2 of 19 (11%). We found no loss of heterozygosity at the loci on chromosomes 11, 13, or 17 in tumor tissue from patients with localized renal cell carcinoma (N = 5). These data suggest the existence of a tumor suppressor gene on chromosome 3p which may be essential to the genesis of sporadic renal cell carcinoma and that other tumor suppressor genes are associated with progression of this malignancy.

Published
1991

30. A new polymorphic probe on chromosome 3p: lambda LIB43-55' (D3S728)

Author

Latif F, Gm, Glenn, Tory K, Hiltrud Brauch, Delisio J, Hampsch K, Ml, Orcutt, Zbar B, and Mi, Lerman

Subjects
Heterozygote, Polymorphism, Genetic, Bacterial Proteins, Chromosome Mapping, Humans, Chromosomes, Human, Pair 3, DNA Probes, Deoxyribonucleases, Type II Site-Specific, Deoxyribonuclease HpaII

31. A new polymorphic probe on chromosome 3p: lambda LIB38-85 (D3S625)

Author

Latif F, Gm, Glenn, Hiltrud Brauch, Delisio J, Hampsch K, Ml, Orcutt, Zbar B, and Mi, Lerman

Subjects
Heterozygote, Polymorphism, Genetic, Deoxyribonuclease BamHI, Humans, Taq Polymerase, Chromosomes, Human, Pair 3, DNA-Directed DNA Polymerase, DNA Probes

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