1. [Resistance of causative agents of uncomplicated urinary tract infections in Russia].
- Author
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Rafal'skiĭ VV, Strachunskiĭ LS, Babkin PA, Valenskaia VS, Gabbasova LA, Dmitrieva OB, Emel'ianova IV, Krupin VN, Malev IV, Petrov SB, Rokhlikov IM, Furletova NM, and Khaĭrullov AS
- Subjects
- Adolescent, Adult, Anti-Bacterial Agents pharmacology, Female, Gram-Negative Bacteria isolation & purification, Gram-Negative Bacterial Infections epidemiology, Gram-Negative Bacterial Infections etiology, Gram-Positive Bacteria isolation & purification, Gram-Positive Bacterial Infections epidemiology, Gram-Positive Bacterial Infections etiology, Humans, Male, Microbial Sensitivity Tests, Middle Aged, Prospective Studies, Urinary Tract Infections epidemiology, Urinary Tract Infections etiology, Urine microbiology, Drug Resistance, Multiple, Bacterial drug effects, Gram-Negative Bacteria drug effects, Gram-Negative Bacterial Infections microbiology, Gram-Positive Bacteria drug effects, Gram-Positive Bacterial Infections microbiology, Urinary Tract Infections microbiology
- Abstract
A prospective epidemiological study of the spectrum of causative agents (CA) of uncomplicated urinary tract infections (UTI) in adult patients and CA resistance to antimicrobial drugs was conducted in nine cities of the Russian Federation in 2004-2005. Minimum inhibiting concentrations were ascertained by dilution in agar according to NCCLS (2000-2002) recommendations. The study has found that uncomplicated UTI are most frequently caused by E.coli (73.9%). Other CA occur much less frequently: K.pneumoniae--6.4%, E. faecalis--4.4%, S. epidermidis--4.1%, Staphylococcus spp--3.4%, others--2% patients. E. coli demonstrated high resistance to ampicilline (33.1%), co-trimoxasol (19.4%). Most active against E. coli were fluoroquinolones (norfloxacin, ciprofloxacin, levofloxacine), the resistance being 4.8%; cefalosporins of the second and third generation (cefuroxim, ceftibuten), nitrofurantoin, no resistant strains were found.
- Published
- 2006