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Your search keyword '"Hou SL"' showing total 4 results
Start Over Author "Hou SL" Topic drugs, chinese herbal
4 results on '"Hou SL"'

1. [Effect of shu di-huang on the transmitter and receptor of amino acid in brain and learning and memory of dementia model].

Author

Cui Y, Yan ZH, Hou SL, and Chang ZF

Subjects
Animals, Arcuate Nucleus of Hypothalamus drug effects, Dementia chemically induced, Drugs, Chinese Herbal isolation & purification, Female, Male, Maze Learning drug effects, Memory drug effects, Mice, Plants, Medicinal chemistry, Rats, Rats, Sprague-Dawley, Receptors, N-Methyl-D-Aspartate metabolism, Dementia physiopathology, Drugs, Chinese Herbal pharmacology, Hippocampus metabolism, Receptors, GABA metabolism, Rehmannia chemistry
Abstract

Objective: To observe the mechanism of SHU-Dihuang on the function of learning and memory., Method: On the dementia model mouse caused by AlCl3 and the rats model damaged thalamic arcuate nucleus with MSG, we observed the function of learning and memory by step down task and Morris water maze task, mensurated the content of glutamic acid and gamma-aminobutyric acid by TLC, and observed the expression of NMDAR1 and GABAR in hippocampi by immunohistochemical means., Result: Shu Di Huang could decrease the times of mistakes and prolong the incubation period in step down task, and shorten the incubation period of seeking the platform in Morris water maze task. Shu Di Huang could adjust the content of Glu and GABA in brain, and increase the expression of hippocampal NMDAR1 and GABAR as well., Conclusion: Shu Di Huang can improve the function of learning and memory of dementia animal model, and its mechanism may be related to the adjustment of the content of Glu and GABA in brain, and increase of the expression of hippocampal NMDAR1 and GABAR.

Published
2003

2. [Effect of shu di-huang on the expression of c-fos and NGF in hippocampi and learning and memory of rats damaged thalamic arcuate nucleus].

Author

Cui Y, Hou SL, Yan ZH, and Chang ZF

Subjects
Animals, Arcuate Nucleus of Hypothalamus drug effects, Drugs, Chinese Herbal isolation & purification, Genes, fos, Hippocampus metabolism, Male, Maze Learning drug effects, Nerve Growth Factor genetics, Plants, Medicinal chemistry, Proto-Oncogene Proteins c-fos genetics, Rats, Rats, Sprague-Dawley, Sodium Glutamate, Drugs, Chinese Herbal pharmacology, Memory drug effects, Nerve Growth Factor biosynthesis, Proto-Oncogene Proteins c-fos biosynthesis, Rehmannia chemistry
Abstract

Objective: To study the mechanism of Shu Di-huang in improving the function of learning and memory., Method: On the rats model with thalamic arcuate nucleus dameged by MSG, the improving function of Shu Di-huang on learning and memory was observed by step down task and Morris water maze task, and the expression of c-fos and NGF in hippocampi was observed by immunohistochemical means., Result: Shu Di-huang could decrease the times of mistakes and prolong the incubation period in step down task, and shorten the incubation period of seeking the platform, and improve the percentage rate through the platform position in Morris water maze task. Shu Di-huang also increase the expression of hippocampal NGF, c-fos., Conclusion: Shu Di-huang can improve the function of learning and memory of MSG rats, and its mechanism may be related with the increase of the expression of hippocampal c-fos and NGF.

Published
2003

3. [Intelligence enhancement of radix Rehmanniae praeparata and some comments on its research].

Author

Cui Y, Yan ZH, Hou SL, and Chang ZF

Subjects
Alzheimer Disease drug therapy, Animals, Antioxidants pharmacology, Calcium Channel Blockers pharmacology, Hot Temperature, Humans, Hypothalamo-Hypophyseal System drug effects, Phytotherapy, Pituitary-Adrenal System drug effects, Drugs, Chinese Herbal pharmacology, Learning drug effects, Plants, Medicinal chemistry, Rehmannia chemistry
Published
2002

4. [Experimental study on effect of sanmiao mixture capsules on prostate hyperplasia in mice and rats].

Author

Hou SL, Cui Y, Ma AL, Zhao J, Xu FX, Yuan XR, and Yang CB

Subjects
Acid Phosphatase blood, Animals, Estradiol blood, Male, Mice, Plants, Medicinal, Prostate pathology, Random Allocation, Rats, Rats, Sprague-Dawley, Testosterone, Drugs, Chinese Herbal pharmacology, Phytotherapy, Prostatic Hyperplasia blood, Prostatic Hyperplasia chemically induced, Prostatic Hyperplasia drug therapy
Abstract

Objective: To observe the effect of Sanmiao Mixture Capsules(SMC) on prostate hyperplasia in mice and rats., Method: The model of prostate hyperplasia was made by injecting testosterone propionate in to male mice(5 g.kg-1.d-1, 21 d) and rats(3 g.kg-1.d-1, 14 d). The treated group was administered SMC(mice: 36.3 g.kg-1 and 18.2 g.kg-1; rats: 25.2 g.kg-1 and 12.6 g.kg-1), the normal control group 1.9 g.kg-1, and the model control group NS. hours after the last administration serum tests were carried out on E2, AKP and Zn2+. Then the animals were killed, prostates taken out and weighed, index of prostate was calculated and pathological examination performed., Result: In the SMC treated group, the prostate weight and index were lowered(P < 0.01) the mean activation of E2 was raised, and the mean concentration of AKP and Zn2+ was inhibited (P < 0.01)., Conclusion: SMC are helpful in checking prostate hyperplasia in mice and rats, the mechanism being probably related to the raising of activation of E2 as well as to the inhibition of concentration of AKP and Zn2+.

Published
2000

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