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Your search keyword '"intermediate age related macular degeneration"' showing total 2 results
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2 results on '"intermediate age related macular degeneration"'

1. Optical coherence tomography biomarkers in early and intermediate age‐related macular degeneration: A clinical guide.

Author

Vidal‐Oliver, Lourdes, Montolío‐Marzo, Elena, Gallego‐Pinazo, Roberto, and Dolz‐Marco, Rosa

Subjects
*MACULAR degeneration, *OPTICAL coherence tomography, *OLDER people, *SCIENCE publishing, *VISION disorders
Abstract

Advanced forms of age‐related macular degeneration (AMD), characterised by atrophic and neovascular changes, are a leading cause of vision loss in the elderly population worldwide. Prior to the development of advanced AMD, a myriad of risk factors from the early and intermediate stages of AMD have been published in the scientific literature over the last years. The ability to precisely recognise structural and anatomical changes in the ageing macula, altogether with the understanding of the individual risk implications of each one of them is key for an accurate and personalised diagnostic assessment. The present review aims to summarise updated evidence of the relative risk conferred by diverse macular signs, commonly seen on optical coherence tomography, in terms of progression to geographic atrophy or macular neovascularization. This information may also serve as a basis for tailored follow‐up monitoring visits. [ABSTRACT FROM AUTHOR]

Published
2024
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2. Correlation between retinal function and microstructural foveal changes in intermediate age related macular degeneration

Author

Carmela Carnevale, Serena Fragiotta, Enzo Maria Vingolo, and Alessandro Cutini

Subjects
0301 basic medicine, medicine.medical_specialty, Drusen, Logistic regression, Microperimetry, Spectral domain optical coherence tomography, Correlation, 03 medical and health sciences, chemistry.chemical_compound, Bivariate contour ellipse area, 0302 clinical medicine, lcsh:Ophthalmology, Ophthalmology, medicine, Retinal sensitivity, Intermediate age related macular degeneration, External limiting membrane, Rank correlation, business.industry, Retinal, Macular degeneration, medicine.disease, bivariate contour ellipse area, intermediate age related macular degeneration, microperimetry, retinal sensitivity, spectral domain optical coherence tomography, eye diseases, 030104 developmental biology, medicine.anatomical_structure, chemistry, lcsh:RE1-994, 030221 ophthalmology & optometry, Optometry, Original Article, sense organs, business
Abstract

Purpose To assess foveal microstructural changes influencing retinal sensitivity (RS) and fixation stability using microperimeter MP-1 in intermediate age-related macular degeneration (AMD). Methods In this cross-sectional study, 22 eyes of 22 patients (mean age: 75 ± 9.02 years) with intermediate AMD were enrolled. Retinal sensitivity and bivariate contour ellipse area (BCEA) were obtained by microperimetry MP-1 (Humphrey 10-2 68-loci grid) under mesopic conditions. Drusen type, drusenoid pigment epithelial detachment, hyperreflective foci (HF), integrity of external limiting membrane (ELM), inner ellipsoid zone (ISel), RPE/Bruch’s membrane complex (RPE/B) and subfoveal choroidal thickness were analyzed in the foveal region and compared with RS and BCEA. Spearman’s rank correlation coefficient was used to evaluate the relationship between variables. Logistic regression analysis was also used to assess morphological predictor influencing RS or BCEA. Results RS was strongly and inversely related with the presence of HF (r = −0.66, P = 0.001), integrity of ELM (r = −0.70, P

Published
2017
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