Search

Eating disorders (EDs) are a kind of chronic disease with high relapse rate and heavy disease burden. Patients with EDS have neurocognitive deficits related to executive function, among which the main manifestations are abnormal attentional bias and inhibitory control. Event-related potential studies are being undertaken to explore the underlying neural mechanism of cognitive abnormalities in EDS. This paper reviews the research of event-related potentials in EDs from the aspect of attentional bias and inhibition control. Suggestions for the future diagnosis and treatment programs based on neurocognitive mechanism are provided. [ABSTRACT FROM AUTHOR]

Objective: To explore the characteristic of cognitive flexibility in young female patients with eating disorders (EDs）,including anorexia nervosa (AN) and bulimia nervosa (BN）,and its relationship with the clinical features of ED. Methods : Ninety-two young female patients with EDs, including 28 patients with AN and 64 patients with BN, and 38 normal controls were enrolled.Cognitive flexibility was assessed with percentage of persistent errors (PPE) and percentage of persistent responses (PPR) of the Wisconsin Card Sorting Test (WCST）,and clinical features of ED by using the Eating Disorder Inventory-1 (EDI-1）.Results:The PPE[ (5.0±4.7) % vs. (2.8±2.8) %,P <0.01] and PPR[ (11.7±7.8) % vs. (6.4±5.9) %,P <0.001] were higher in ED group than in normal control group, but the differences on PPE[ (5.5±5.4) % vs. (5.0±4.5) %,P> 0.05] and PPR[ (11.2±7.8) % vs. (11.1±7.3）%,P> 0.05] between AN and BN groups were not statistically significant. The PPE (r=0.21,P <0.05) and PPR (r=0.27,P <0.01) were positively correlated with the EDI-1 total scores.PPR was positively correlated with the frequency of appetite suppressant use (r=0.28,P <0.05) and skipping several meals (r=0.30,P <0.01) in the ED group. Conclusion: The presence of cognitive flexibility deficits in young female patients with eating disorders, and their correlation with clinical features of eating disorders further support the possibility of being an endophenotype of eating disorders. [ABSTRACT FROM AUTHOR]

Objective: To evaluate the validity and reliability of the Identity and Eating Disorders questionnaire (IDEA) in China. Methods: Totally 187 patients with eating disorders meeting diagnostic criteria of DSM-IV and 60 normal controls were assessed with IDEA and the Eating Disorder Inventory (EDI-1). Thirty patients were re¬tested with IDEA within 2 weeks . Results: The 4 factors were extracted from the items by exploratory factor analy¬ sis with cumulative vaiance being 63.3%. There were 3 items drifting, which were deleted during later analy¬sis .The intraclass correlation coefficient of IDEA and EDI-1 was 0 . 8 6 . The total scores and the 4 subscale scores of IDEA were higher in the patient group than in the control group (Ps <0. 001). The Cronbach a coefficients of the I¬DEA was 0. 95, and the splitting half-reliability coefficient was 0. 93. Pearson correlation coefficient of retest was 0. 86. Conclusion: The Chinese version of IDEAhas good validity and reliability for evaluating eating disorders and related psychological characteristics in patients with eating disorders. [ABSTRACT FROM AUTHOR]