1. Macroglossia and generalized edema not due to hypothyroidism.
- Author
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Alimoglu Y, Sacli FS, and Erdamar S
- Subjects
- Aged, Amyloidosis diagnosis, Biopsy, Deglutition Disorders etiology, Humans, Hypothyroidism diagnosis, Male, Thyrotropin blood, Amyloidosis complications, Amyloidosis pathology, Edema etiology, Macroglossia etiology
- Abstract
We present a 69-year-old male patient with the macroglossia, dysphagia and generalized edema. He was seen previously by other physicians and diagnosed as hypothyroidism. With thyroid stimulating hormone in normal range, tongue biopsy revealed primary systemic amyloidosis. Amyloidosis is the most common cause of macroglossia. Primary systemic amyloidosis should be suspected when laboratory does not support hypothyroidism especially if the enlarged tongue is firm and additional findings are present.
- Published
- 2012
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