5 results on '"Beatrice Di Capua"'
Search Results
2. SUPeRO: A Multidimensional Approach to Prevent and Manage Oncological Frailty in a Radiation Oncology Unit
- Author
-
Beatrice Di Capua, Marialuisa Iervolino, Alessandra Rocconi, Serena Bracci, Elisa Marconi, Loredana Dinapoli, Francesco Presta, Maria Antonietta Gambacorta, Luca Tagliaferri, Fabio Marazzi, Vincenzo Valentini, and Giuseppe Ferdinando Colloca more...
- Subjects
supportive care ,geriatric assessment ,oncology ,elderly ,frailty ,geriatric oncology ,personalized medicine ,General Medicine ,Settore MED/36 - DIAGNOSTICA PER IMMAGINI E RADIOTERAPIA - Abstract
Currently, the management of older cancer patients is directed by a personalized approach and, where possible, a tailor-made treatment. Based on our previous experiences and considering the opportunity of combining a geriatric department and a radiation-oncology department, we have developed a path that follows the patient from the beginning of the treatment, taking into account the complications/late toxicities and the survivors. This study aimed to evaluate the impact of remodeling and restructuring some oncology, radiotherapy, and geriatrics services based on the primary evidence for managing older cancer patients. In 2020, Gemelli ART underwent 60,319 radiation-oncology treatments, admitted 943 patients in the radiation-oncology and supportive care ward, and treated and followed 15,268 patients in clinics. The average length of stay of the admitted patients was reduced from 20.6 days to 13.2 days. In 2021, 1196 patients were assessed for frailty, 847 were admitted for toxicity, and 349 patients were evaluated within the geriatric oncology and supportive care outpatient clinic, and it was found that 59.2% were fit, 31.6% were vulnerable, and 9.2% were frail. This experience has shown a reduction in hospitalizations and the average hospital stay of patients in the case of side effects, a high toxicity to treatments, and the possibility of treating patients with a high level of complexity. This approach should represent the future target of geriatric oncology with the global management of older or complex patients with cancer. more...
- Published
- 2022
Catalog
3. Perspectives and limits of cancer treatment in an oldest old population
- Author
-
Luca Tagliaferri, Vincenzo Valentini, Giuseppe Colloca, Emanuele Rocco Villani, Maria Antonietta Gambacorta, Roberto Bernabei, Andrea Bellieni, Domenico Fusco, and Beatrice Di Capua
- Subjects
Pediatrics ,medicine.medical_specialty ,Aging ,Population ,Disease ,Comorbidity ,Radiation oncology ,Oldest old ,03 medical and health sciences ,0302 clinical medicine ,Elderly ,Neoplasms ,80 and over ,medicine ,Humans ,030212 general & internal medicine ,education ,Aged ,Settore MED/36 - DIAGNOSTICA PER IMMAGINI E RADIOTERAPIA ,Cancer ,Retrospective Studies ,Polypharmacy ,Aged, 80 and over ,education.field_of_study ,Performance status ,business.industry ,Retrospective cohort study ,medicine.disease ,Personalized medicine ,Geriatric oncology ,030220 oncology & carcinogenesis ,Original Article ,Geriatrics and Gerontology ,business - Abstract
Background Population of oldest old will grow dramatically in the next future and cancer, physiologically related to aging, will be very prevalent among them. Lack of evidence is a huge problem to manage cancer in oldest old and will be more and more in the next years. Aims Our purpose was to investigate the characteristics of a population of oldest old patients with cancer treated in the Radiation Oncology Unit of Fondazione Policlinico A. Gemelli IRCCS. Methods We conducted a retrospective study. The primary outcome was to evaluate which characteristics of the population could influence the choice of oncological treatment (with radical or non-radical intent). Results We identified a total of 348 patients: 140 were on follow-up; 177 were under treatment; 31 were considered not eligible for treatments. Patients under treatment had a high comorbidity index (mean Charlson Comorbidity Index 5.4), and a high prevalence of polypharmacy (mean number of drugs 5.6). More than half (53.1%) was treated with radical intent. Patients treated with radical intent were 1 year younger (87.1 years old vs 88.1 years old), more performant (ECOG 0.7 vs 1.3), and had less prevalence of metastatic neoplasia (6.4% vs 34.9%); comorbidities and drugs did not show differences in the two groups. Conclusion Oldest old, usually not considered in international guidelines, are treated for oncological disease, often with radical intent. The treatment seems not to be tailored considering comorbidities but on performance status. more...
- Published
- 2021
4. The importance of geriatric and surgical co-management of elderly in muscoloskeletal oncology: A literature review
- Author
-
Andrea Bellieni, Domenico Fusco, Carlo Perisano, Raffaele Vitiello, Beatrice Di Capua, Giuseppe Colloca, Maria Serena Oliva, Marco Lillo, Giulio Maccauro, and Silvia Careri
- Subjects
Orthopedic surgery ,orthogeriatric ,medicine.medical_specialty ,education.field_of_study ,business.industry ,Soft tissue sarcoma ,muscoloskeletal ,Population ,Cancer ,Sarcoma ,Geriatric assessment ,Review ,medicine.disease ,elderly ,medicine ,score ,Orthopedics and Sports Medicine ,Intensive care medicine ,business ,education ,RD701-811 - Abstract
People over 65 years old are the fastestgrowing part of the population and also the most common population in oncological practice. The geriatric co-assessment when involved in the management of orthopedic elderly patients could improve the survival and clinical outcomes of the patients. The aim of this review is to understand the importance of comprehensive geriatric assessment in elderly cancer orthopaedic patients affected by bone and soft tissue sarcoma in order to apply it and identify the mean surgical prognostic factors of this population. more...
- Published
- 2020
- Full Text
- View/download PDF
5. Management of The Elderly Cancer Patients Complexity: The Radiation Oncology Potential
- Author
-
Giuseppe Colloca, Maria Antonietta Gambacorta, William C. Cho, Silvio Monfardini, Beatrice Di Capua, Lodovico Balducci, Andrea Bellieni, Luca Tagliaferri, Vincenzo Valentini, Roberto Bernabei, and Vito Lanzotti more...
- Subjects
0301 basic medicine ,medicine.medical_specialty ,Review ,frailty ,elderly ,Pathology and Forensic Medicine ,sarcopenia ,03 medical and health sciences ,0302 clinical medicine ,Quality of life (healthcare) ,Radiation oncology ,medicine ,cancer ,Frail elderly ,Intensive care medicine ,Settore MED/36 - DIAGNOSTICA PER IMMAGINI E RADIOTERAPIA ,business.industry ,Cancer ,radiation oncology ,Cell Biology ,medicine.disease ,personalized treatment ,humanities ,Clinical trial ,030104 developmental biology ,quality of life ,Sarcopenia ,Life expectancy ,Neurology (clinical) ,Active treatment ,Geriatrics and Gerontology ,complexity ,business ,030217 neurology & neurosurgery - Abstract
Radiation oncology has the potential to be an excellent option for the frail elderly cancer patients because of its limited systemic toxicities. It can be effective for curative, prophylactic, disease control or palliative purposes. Currently about 60% of all cancer patients undergoing active treatment at some point receive radiation treatment. However, though widely used, there are limited clinical trials strictly designed for the elderly. This paper will review the key points in the assessment and treatment of elderly cancer patient including quality of life, active life expectancy, cognitive performance, frailty, sarcopenia and how the new technologies can help to reach the key goal of maintaining autonomy and independence for the elderly cancer patient. more...
- Published
- 2020
- Full Text
- View/download PDF
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.