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Cardio vascular disease threatens human life with higher mortality rate. Therefore it is quite important to monitor. An arrhythmia is an abnormal heart beat and rhythm which causes the disease. The best tool to find the heart rhythm of heart is Electro Cardiogram (ECG) which provides information about the different types of arrhythmias. This paper aims at proposing an automatic framework by employing multi-domain features to classify ECG signals. Proposed work uses optimum method of feature selection to improvise the efficiency of the classification process. A hybrid optimization algorithm is used for feature selection and proposed to optimize the parameters of the existing Support Vector Machine (SVM) classifier. Proposed hybrid optimization algorithm was developed using Particle Swarm Optimization (PSO) and Migration Modified Biogeography Based Optimization (MMBBO) algorithm. Algorithm provides an improved solution to the optimizing the parameters of ECG signals. Results are evaluated by implementing in MATLAB software and the performance is justified with comparative analysis. The proposed framework enhances the process of automatic prediction of various arrhythmias or rhythm abnormalities which performs in gaining better accuracy. For data sets, the average classification accuracy of this method is 97.89%. This result is an improvement of 4–5% over the comparison of other methods. [ABSTRACT FROM AUTHOR]