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Start Over Author "Xindi Jia" Topic electrochemistry
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1. A sensitive and simple competitive nanozyme-linked apta-sorbent assay for the dual-mode detection of ochratoxin A

Author

Min Li, Hao Wang, Xiaodi Yu, Xindi Jia, Chao Zhu, Jiahui Liu, Fan Zhang, Zilei Chen, Mengmeng Yan, and Qinzheng Yang

Subjects
Limit of Detection, Tandem Mass Spectrometry, Electrochemistry, Environmental Chemistry, Colorimetry, Aptamers, Nucleotide, Ochratoxins, Biochemistry, Spectroscopy, Analytical Chemistry
Abstract

The enzyme-linked apta-sorbent assay (ELASA) is widely used for the detection of small-molecule compounds as a result of low cost and reagent stability of aptamers. However, enzyme labels used in ELASA still suffer from some drawbacks, such as high production cost and limited stability. To overcome the drawbacks, we reported a nanozyme-linked apta-sorbent assay (NLASA) coupled with surface-enhanced Raman scattering (SERS)-colorimetric dual-mode detection. For nanozyme labels, Pd-Pt bimetallic nanocrystals (Pd-Pt NRs) could catalyze 3,3',5,5'-tetramethylbenzidine (TMB) to blue TMB

Published
2022

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