1. United Kingdom Biobank (UK Biobank): JACC Focus Seminar 6/8.
- Author
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Caleyachetty R, Littlejohns T, Lacey B, Bešević J, Conroy M, Collins R, and Allen N
- Subjects
- Adult, Diagnostic Imaging, Female, Heart Disease Risk Factors, Humans, Male, Middle Aged, United Kingdom, Biological Specimen Banks organization & administration, Cardiovascular Diseases diagnosis, Cardiovascular Diseases epidemiology, Cardiovascular Diseases genetics, Electronic Health Records, Genomics, Proteomics, Public Health Informatics
- Abstract
An increasing number of people are now living with cardiovascular disease (CVD), with concomitant CVD-related hospitalizations, operations, and prescriptions. To ultimately deliver optimal cardiovascular care, access to population-based biobanks with data on multiomics, phenotypes, and lifestyle risk factors are crucial. UK Biobank is a cohort study that incorporated data between 2006 and 2010 from over half a million individuals (40 to 69 years of age) at recruitment from across the United Kingdom. As one of the most accessible, largest, and in-depth cohort studies in the world, UK Biobank continues to enhance the resource with the addition of data from various omics platforms (eg, genomics, metabolomics, proteomics), multimodal imaging, self-reported risk factors and health outcomes, and linkage to electronic health records. The vision of UK Biobank is to allow as many researchers as possible to apply their expertise and imagination to undertake research to prevent, diagnose, and treat a wide range of chronic conditions, including CVD., Competing Interests: Funding Support and Author Disclosures The authors have reported that they have no relationships relevant to the contents of this paper to disclose., (Copyright © 2021. Published by Elsevier Inc.)
- Published
- 2021
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