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Your search keyword '"Christoph Schulreich"' showing total 3 results
Start Over Author "Christoph Schulreich" Topic emulsions
3 results on '"Christoph Schulreich"'

1. Extraction of model contaminants from solid surfaces by environmentally compatible microemulsions

Author

Joachim Koetz, Angelika Kostevic, Regine von Klitzing, Salomé Vargas-Ruiz, Martin Jung, Thomas Hellweg, Brigitte Tiersch, Christoph Schulreich, Sergej Kakorin, and Stefan Wellert

Subjects
Materials science, Chromatography, Solid surface, Solid Phase Extraction, Kinetics, Extraction (chemistry), Kinetic analysis, 02 engineering and technology, Human decontamination, Contamination, 010402 general chemistry, 021001 nanoscience & nanotechnology, 01 natural sciences, 0104 chemical sciences, Surfaces, Coatings and Films, Electronic, Optical and Magnetic Materials, Biomaterials, Colloid and Surface Chemistry, Models, Chemical, Scientific method, Institut für Chemie, Emulsions, Microemulsion, 0210 nano-technology
Abstract

In the present contribution, we evaluate the efficiency of eco-friendly microemulsions to decontaminate solid surfaces by monitoring the extraction of non-toxic simulants of sulfur mustard out of model surfaces. The extraction process of the non-toxic simulants has been monitored by means of spectroscopic and chromatographic techniques. The kinetics of the removal process was analyzed by different empirical models. Based on the analysis of the kinetics, we can assess the influence of the amounts of oil and water and the microemulsion structure on the extraction process. (C) 2016 Elsevier Inc. All rights reserved.

Published
2016

2. An enzyme containing microemulsion based on skin friendly oil and surfactant as decontamination medium for organo phosphates: Phase behavior, structure, and enzyme activity

Author

Christoph Schulreich, Marc-Michael Blum, Kai Kehe, Alain Lapp, Jürgen Gäb, Andras Richardt, Ralf Stehle, Thomas Hellweg, and Stefan Wellert

Subjects
Small angle neutron scattering, DFPase, Biomaterials, Hydrolysis, Surface-Active Agents, Colloid and Surface Chemistry, Organophosphorus Compounds, Pulmonary surfactant, Dynamic light scattering, Organic chemistry, Microemulsion, Diisopropyl-fluorophosphatase, Decontamination, Skin, GB, biology, Molecular Structure, Chemistry, Protein, Nuclear magnetic resonance spectroscopy, Small-angle neutron scattering, Enzyme assay, Surfaces, Coatings and Films, Electronic, Optical and Magnetic Materials, biology.protein, Emulsions, Oils, Nuclear chemistry
Abstract

The present contribution presents a microemulsion system containing cosmetic oil and sugar surfactant and the enzyme diisopropyl fluorophosphatase (DFPase) as active agent for the decontamination of human skin. The bicontinuous structure and the physical properties of the microemulsion are characterized by dynamic light scattering and small angle neutron scattering. The DFPase from the squid Loligo vulgaris is catalyzing the hydrolysis of highly toxic organophosphates. The effect of the enzyme on the structure of the microemulsion is investigated. Moreover, the enzyme/microemulsion system is also studied with respect to its activity using nuclear magnetic resonance spectroscopy leading to promising results. A fast decomposition of the nerve agent sarin is achieved. (C) 2013 Elsevier Inc. All rights reserved.

Published
2014
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3. The DFPase from Loligo vulgaris in sugar surfactant-based bicontinuous microemulsions: structure, dynamics, and enzyme activity

Author

Marc-Michael Blum, Olaf Holderer, Alain Lapp, Jürgen Gäb, Joachim Koetz, Ralf Stehle, André Richardt, Christoph Schulreich, Stefan Wellert, Brigtte Tiersch, and Thomas Hellweg

Subjects
Biophysics, Carbohydrates, Loligo, Enzyme catalysis, Hydrolysis, Surface-Active Agents, Dynamic light scattering, Scattering, Small Angle, Native state, Animals, Microemulsion, Diisopropyl-fluorophosphatase, biology, Chemistry, General Medicine, Combinatorial chemistry, Enzyme assay, Enzyme structure, Solutions, Crystallography, Neutron Diffraction, Phosphoric Triester Hydrolases, biology.protein, Microscopy, Electron, Scanning, Institut für Chemie, Emulsions
Abstract

The enzyme diisopropyl fluorophosphatase (DFPase) from the squid Loligo vulgaris is of great interest because of its ability to catalyze the hydrolysis of highly toxic organophosphates. In this work, the enzyme structure in solution (native state) was studied by use of different scattering methods. The results are compared with those from hydrodynamic model calculations based on the DFPase crystal structure. Bicontinuous microemulsions made of sugar surfactants are discussed as host systems for the DFPase. The microemulsion remains stable in the presence of the enzyme, which is shown by means of scattering experiments. Moreover, activity assays reveal that the DFPase still has high activity in this complex reaction medium. To complement the scattering experiments cryo-SEM was also employed to study the microemulsion structure.

Published
2010

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