1. Facile and efficient electrochemical enantiomer recognition of phenylalanine using β-Cyclodextrin immobilized on reduced graphene oxide.
- Author
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Zaidi, Shabi Abbas
- Subjects
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ENANTIOMERS , *ELECTROCHEMICAL sensors , *PHENYLALANINE , *CYCLODEXTRINS , *GRAPHENE oxide - Abstract
This work demonstrates the facile and efficient preparation protocol of β-Cyclodextrin-reduced graphene oxide modified glassy carbon electrode (β-CD/RGO/GCE) sensor for an impressive chiral selectivity analysis for phenylalanine enantiomers. In this work, the immobilization of β-CD over graphene sheets allows the excellent enantiomer recognition due to the large surface area and high conductivity of graphene sheets and extraordinary supramolecular (host-guest interaction) property of β-CD. The proposed sensor was well characterized by scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR), and electrochemical impedance spectroscopy (EIS) techniques. The analytical studies demonstrated that the β-CD/RGO/GCE exhibit superior chiral recognition toward L -phenylalanine as compared to D -phenylalanine. Under optimum conditions, the developed sensor displayed a good linear range from 0.4 to 40 µM with the limit of detection (LOD) values of 0.10 µM and 0.15 µM for l - and D -phenylalanine, respectively. Furthermore, the proposed sensor exhibits good stability and regeneration capacity. Thus, the as-synthesized material can be exploited for electrochemical enantiomer recognition successfully. [ABSTRACT FROM AUTHOR]
- Published
- 2017
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