1. The vitamin E-binding protein afamin is altered significantly in the peritoneal fluid of women with endometriosis.
- Author
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Seeber BE, Czech T, Buchner H, Barnhart KT, Seger C, Daxenbichler G, Wildt L, and Dieplinger H
- Subjects
- Adolescent, Adult, Ascitic Fluid chemistry, Ascitic Fluid pathology, Carrier Proteins analysis, Carrier Proteins blood, Case-Control Studies, Endometriosis blood, Endometriosis pathology, Female, Glycoproteins analysis, Glycoproteins blood, Humans, Middle Aged, Osmolar Concentration, Oxidative Stress physiology, Peritoneal Diseases blood, Peritoneal Diseases pathology, Serum Albumin analysis, Serum Albumin, Human, Vitamin E blood, Vitamin E metabolism, Young Adult, Ascitic Fluid metabolism, Carrier Proteins metabolism, Endometriosis metabolism, Glycoproteins metabolism, Peritoneal Diseases metabolism, Serum Albumin metabolism
- Abstract
The objective of this case-control study of 242 reproductive-age women was to determine the concentration of afamin in the serum and peritoneal fluid of women with and without endometriosis and to test afamin as a diagnostic marker of endometriosis. Afamin levels were altered significantly in the peritoneal fluid of women with endometriosis compared with disease-free controls, correlated with vitamin E levels, and are consistent with increased oxidative stress in the peritoneal cavity of women with endometriosis., (Copyright © 2010 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.)
- Published
- 2010
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