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Colorectal cancer is one of the most frequent cancers from over the world (1). Colonoscopy is for a very long time accepted as the most efficacy method for colorectal diagnosis and prevention. Neoplasic colonic lesions are polipoid type and non-polypoid type. Japanese classification of superficial colonic lesions (0 type) is unanimity accepted. Colonic polyps are easy to recognize. Endoscopic resection of polyps is necessary for correct diagnosis and treatment. Non-polypoid tumors are, sometimes difficult to recognize. Laterally spreading tumors typically extend laterally and circumferentially rather than vertically along the colonic wall and the frequency of invasive carcinoma is lower than for polypoid lesions of similar size. Depressed type has a high risk of malignancy even at small size. Magnification chromoendoscopy, narrow-band imaging and confocal endoscopy can improve the detection of colonic lesions and differentiating between malign and benign. [ABSTRACT FROM AUTHOR]

The article presents a case study of giant inflammatory pseudotumor of the larynx in an 81-year-old man presented with significant cardiovascular co-morbidities, hoarseness, and dysphagia. The patient was treated endoscopically through a gastroenterologist using submucosal dissection. It suggests that submucosal dissection and pedical resection can remove giant pedunculated submucosal tumor masses in the larynx endoscopically in gastrointestinal endoscopy.

A letter to the editor is presented in response to articles on the clinical efficiency of peroral endoscopic myotomy procedure for achalasia in the previous issues .